Overview
Dr Daniela Patinha is a teaching-focused Senior Lecturer within the College of Medicine and Health. She has a broad portfolio of teaching responsibilities across the BSc Medical Science and Bachelor of Medicine and Bachelor of Surgery (BMBS) programmes.
She joined the University of Exeter in January 2017, initially as a Research Fellow. Over the subsequent years she transitioned to a teaching-focused role. Her research background is in integrative physiology aiming to phenotype and integrate complex organ function in cardiovascular and renal pathophysiology. Her multi-disciplinary approach and expertise, enables the integration of concepts from basic science, drug development and (pre-) clinical studies.
Career
Dr Daniela Patinha completed her PhD in Metabolism in 2013. In the years that followed she has been developing as an educator and a researcher in international teams in Portugal, Sweden, New Zealand and UK.
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Publications
Journal articles
Vara D, Tarafdar A, Celikag M, Souto Patinha D, Gulacsy CE, Hounslea E, Warren Z, Ferreira B, Koeners MP, Caggiano L, et al (In Press). NADPH oxidase 1 is a novel pharmacological target for the development of an antiplatelet drug without bleeding side effects. The FASEB Journal
Patinha D, Abreu C, Carvalho C, Cunha OM, Mota M, Afonso J, Sousa T, Albino-Teixeira A, Diniz C, Morato M, et al (2020). Adenosine A2A and A3 Receptors as Targets for the Treatment of Hypertensive-Diabetic Nephropathy.
Biomedicines,
8(11).
Abstract.
Author URL.
Patinha D, Carvalho C, Persson P, Pihl L, Fasching A, Friederich‐Persson M, O'Neill J, Palm F (2020). Determinants of renal oxygen metabolism during low Na<sup>+</sup> diet: effect of angiotensin II AT<sub>1</sub> and aldosterone receptor blockade.
The Journal of Physiology,
598(23), 5573-5587.
Abstract.
Patinha D, Carvalho C, Abreu C, Cunha OM, Mota MC, Afonso J, Albino-Teixeira A, Diniz C, Morato M (2019). Diabetes downregulates renal adenosine A2A receptors in an experimental model of hypertension.
PLoS One,
14(5).
Abstract.
Author URL.
Emans TW, Patinha D, Joles JA, Koeners MP, Janssen BJ, Krediet CTP (2018). Angiotensin II-induced hypertension in rats is only transiently accompanied by lower renal oxygenation.
Sci Rep,
8(1).
Abstract.
Author URL.
Patinha D, Pijacka W, Paton JFR, Koeners MP (2017). Cooperative Oxygen Sensing by the Kidney and Carotid Body in Blood Pressure Control.
Front Physiol,
8 Abstract.
Author URL.
O'Neill J, Fasching A, Pihl L, Patinha D, Franzén S, Palm F (2015). Acute SGLT inhibition normalizes O2 tension in the renal cortex but causes hypoxia in the renal medulla in anaesthetized control and diabetic rats.
Am J Physiol Renal Physiol,
309(3), F227-F234.
Abstract.
Author URL.
Patinha D, Afonso J, Sousa T, Morato M, Albino-Teixeira A (2014). Activation of adenosine receptors improves renal antioxidant status in diabetic Wistar but not SHR rats.
Ups J Med Sci,
119(1), 10-18.
Abstract.
Author URL.
Patinha D, Afonso J, Sousa T, Morato M, Albino-Teixeira A (2014). Diabetes-induced increase of renal medullary hydrogen peroxide and urinary angiotensinogen is similar in normotensive and hypertensive rats.
Life Sci,
108(2), 71-79.
Abstract.
Author URL.
Patinha D, Fasching A, Pinho D, Albino-Teixeira A, Morato M, Palm F (2013). Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors.
Am J Physiol Renal Physiol,
304(5), F614-F622.
Abstract.
Author URL.
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Teaching
BSc Medical Sciences
Module Lead: Translational Medical Science (CSC3019)
Personal tutor and Mentor for undergraduate and PhD students
Academic Lead for Employability and Careers (visit our website)
Project Provider and Supervision: Final Year Literature Review
Lecturer provider / SSGL tutor / Marker: Professional Training Year; Integrated Human Physiology; Introduction to Pharmacology; Disease, Diagnostics and Therapeutics; Experimental Design and Statistics; Decolonizing Medicine: An Introduction.
Bachelor of Medicine and Bachelor of Surgery (BMBS)
Academic Theme Lead: Biomedical Science Special Study Units
Lecturer and progress support provider: Special Study Units
Problem Based Learning Tutor
Life Science Resource Centre Lecturer
Modules
2023/24
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