Professor Chris Hyde
Professor of Public Health and Clinical Epidemiology
C.J.Hyde@exeter.ac.uk
6051
+44 (0) 1392 726051
College House 1.22
College House, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK
Overview
Chris Hyde was recruited to Exeter in 2009. He is a lead for research on test evaluation including systematic reviews, economic models and primary research. He directs the Exeter Test Group. He directed PenTAG the team delivering health technology assessments for national policy-making bodies, particularly NICE, from 2009 until 2015. He is a member of the National Screening Committee and was previously a member of NICE's Diagnostic Advisory Committee.
Chris qualified in medicine in 1986 and worked in general medicine until 1990. He then undertook specialist training in Public Health, completing this in 1996. In 1994 he did a placement at the UK Cochrane Centre as part of his specialist training and became interested in using research to inform decisions about health. In 1996 he set up and directed a unit based in the University of Birmingham to support commissioners of health care use research (ARIF) which continued until 2012. He became progressively more active in doing research as well as disseminating it and became Director of the West Midlands Health Technology Assessment Collaboration (WMHTAC) in 2007. He was also closely involved in setting up the NHS Blood & Transplant Systematic Reviews Initiative and has contributed to the work of the Cochrane Collaboration since its inception.
Throughout his career Chris has been variously intrigued and frustrated by research on tests and their interpretation. He has done many systematic reviews and health economic models on a wide variety tests including near patient tests in primary care, novel methods of processing cervical smears, hysteroscopy, tests for predicting preeclampsia and preterm birth, PET/CT scanning for breast cancer and OSNA for sentinel lymph node biopsy in breast cancer. A recurring theme is that test evaluations are often not fit for purpose and provide only indirect evidence about whether a new test will benefit patients and society if introduced. Helping to improve this situation is the main purpose of Chris’s research at UEMS.
Broad research specialisms
- Systematic reviews and meta-analysis
- Health economic modelling
- Health technology assessment
- Test evaluation
- Research dissemination
- Health policy making
Qualifications
- MB BS (St Thomas’s Hospital, London)
- MRCP
- FFPH
Research group links
Research
Research interests
Test evaluation is Chris’s main area of interest. He works closely with a number of clinical groups in UEMS and beyond to support evaluation. Pre-eminent among these is Prof Hattersley’s team. Chris, Jaime Peters and Rob Anderson are using economic modelling alongside a series of clinical studies to assess the effectiveness and cost-effectiveness of systematically testing for genetically determined diabetes (the UNITED project). A similar approach is being used to evaluate the effectiveness and cost-effectiveness of school entry hearing screening working with Prof Fortnum’s audiology group in Nottingham.
Traditional economic modelling and systematic reviewing, independent of new data collection, remains the mainstay of our evaluative approach. I am closely involved with the Cochrane Collaboration Dementia and Cognitive Improvement Group’s work to systematically review accuracy studies on the wide range of tests which have been suggested for dementia. Working with Harriet Hunt I am contributing to an NIHR programme grant on coagulopathy in trauma through systematic reviews on the value of TEG and ROTEM. Our Technology Appraisal Group have recently completed health technology assessments on OSNA for sentinel lymph node biopsy in breast cancer and testing strategies for Lynch syndrome.
Chris is committed to methodological development. He was closely involved with the development of a new evaluation framework for tests by Lavinia Ferrante di Ruffano in Birmingham. Chris and colleagues at UEMS are currently considering whether our existing classifications and descriptions of different research designs for test evaluation are adequate. He contributed to NICE’s methods guidance on the appraisal of tests.
Chris and colleagues are also working directly to translate research into practice through the Peninsula CLAHRC. We have been fostering skill development in systematic reviews of test accuracy using CT coronary angiography and high sensitivity troponin in acute MI as exemplars. Chris helps direct a team exploring the reasons for variation of thyroid function test ordering in primary care as a prelude to an evidence based approach to reducing variation in test use (the UNTEST project). Led by Chris, Zhivko Zhelev undertook an innovative application of cognitive interviewing to the investigation of what readers understand when reading the newly introduced Cochrane reviews of test accuracy.
Chris remains committed to policy making. He leads the Technology Appraisal Report team providing 4 to 6 health technology assessments or appraisals of manufacturer submissions to NICE annually. He also sits on NICE’s Diagnostics Appraisal Committee.
Chris describes his research into the impact of tests on patients as part of the Exeter Test Group and PenTAG (the Peninsula Technology Assesment Group), in the video below.
Research projects
- Effectiveness and cost-effectiveness of screening for lung cancer with low dose CT
Publications
Journal articles
Ukoumunne OC, Hyde C, Ozolins M, Zhelev Z, Errington S, Taylor RS, Benton C, Moody J, Cocking L, Watson J, et al (In Press). A directly comparative two-gate case-control diagnostic accuracy study of the pure tone screen and HearCheck Screener tests for identifying hearing impairment in school children. BMJ Open
Merriel S, Hamilton W, Ball S, Hyde C (In Press). A prospective evaluation of the fourth be Clear on Cancer ‘Blood in Pee’ campaign in England. European Journal of Cancer Care
James-Pemberton P, Shaw A, Lapinska U, Hyde C (In Press). Accuracy and Precision Analysis for a Biophotonic Assay of C-Reactive Protein. The Analyst
Streeter AJ, Lin NX, Crathorne L, Haasova M, Hyde C, Melzer D, Henley W (In Press). Adjusting for unmeasured confounding in non-randomised longitudinal studies: a methodological review. Journal of Clinical Epidemiology
Ball S, Hyde C, Hamilton W, Bright C, Gildea C, Wong K, Paley L, Hill H, Mak V, Moffat J, et al (In Press). An evaluation of a national mass media campaign to raise public awareness of possible lung cancer symptoms in England in 2016 and 2017. British Journal of Cancer
Zhelev Z, Ohtake H, Iwata M, Terasawa T, Rogers M, Peters J, Hyde C (In Press). Diagnostic accuracy of contemporary and high-sensitivity cardiac troponin assays used in serial testing, versus single-sample testing as a comparator, to triage patients suspected of acute non- ST-segment elevation myocardial infarction: a systematic review protocol. BMJ Open Abstract.
Hardwick RJL, Heaton J, Griffiths G, Vaidya B, Child S, Fleming S, Hamilton WT, Tomlinson J, Zhelev Z, Patterson A, et al (In Press). Exploring reasons for variation in ordering thyroid function tests in primary care: a qualitative study. Quality in Primary Care, 22, 256-261. Abstract.
Snowsill TM, Yang H, Griffin E, Long HL, Varley-Campbell J, Coelho H, Robinson S, Hyde C (In Press). Low-dose computed tomography for lung cancer screening in high risk populations: a systematic review and economic evaluation. Health Technology Assessment
Jones AG, mcdonald TJ, Shields BM, Hill AV, Hyde CJ, Knight BA, Hattersley AT (In Press). Markers of beta cell failure predict poor glycemic response to GLP-1 receptor agonist therapy in type 2 diabetes. Diabetes Care
Dennis J, Henley W, Weedon M, Lonergan M, Rodgers L, Jones A, Hamilton W, Sattar N, Janmohamed S, Holman R, et al (In Press). Sex and BMI alter the benefits and risks of sulfonylureas and thiazolidinediones in type 2 diabetes: a framework for evaluating stratification using routine clinical and individual trial data. Diabetes Care
Peters J, Anderson R, Shields B, Hudson M, Shepherd M, McDonald T, Hattersley A, Hyde C (In Press). Strategies to Identify Individuals with Monogenic Diabetes: Results of an Economic Evaluation. BMJ Open
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long H, Medina-Lara A, et al (In Press). The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia (including review of TA142): a systematic review and economic model. Health Technology Assessment Abstract.
McGovern A, Shields B, Hattersley A, Pearson E, Jones AG (In Press). What to do with diabetes therapies when HbA1c lowering is inadequate: add, switch, or continue? a MASTERMIND study. BMC Medicine
Duer E, Yang H, Robinson S, Grigore B, Sandercock J, Snowsill T, Griffin E, Peters J, Hyde C (2023). Do we know enough about the effect of low-dose computed tomography screening for lung cancer on mortality to act? an updated systematic review, meta-analysis and network meta-analysis of randomised controlled trials 2017 to 2021. Diagn Progn Res, 7(1). Abstract. Author URL.
Ferrante di Ruffano L, Harris IM, Zhelev Z, Davenport C, Mallett S, Peters J, Takwoingi Y, Deeks J, Hyde C (2023). Health technology assessment of diagnostic tests: a state of the art review of methods guidance from international organizations. Int J Technol Assess Health Care, 39(1). Abstract. Author URL.
Thomas L, Hyde C, Mullarkey D, Greenhalgh J, Kalsi D, Ko J (2023). Real-world post-deployment performance of a novel machine learning-based digital health technology for skin lesion assessment and suggestions for post-market surveillance. Frontiers in Medicine, 10 Abstract.
Zhelev Z, Peters J, Rogers M, Allen M, Kijauskaite G, Seedat F, Wilkinson E, Hyde C (2023). Test accuracy of artificial intelligence-based grading of fundus images in diabetic retinopathy screening: a systematic review. J Med Screen, 30(3), 97-112. Abstract. Author URL.
Thompson G, Zhelev Z, Hunt H, Hyde C (2022). It was not easy to identify the study design from the title and abstract of articles indexed as diagnostic (test) accuracy studies in EMBASE in 2012 and 2019. J Clin Epidemiol, 144, 102-110. Abstract. Author URL.
Ohtake H, Terasawa T, Zhelev Z, Iwata M, Rogers M, Peters JL, Hyde C (2022). Serial high-sensitivity cardiac troponin testing for the diagnosis of myocardial infarction: a scoping review. BMJ Open, 12(11), e066429-e066429. Abstract.
Ruban-Fell B, Attilakos G, Haskins-Coulter T, Hyde C, Kusel J, Mackie A, Rivero-Arias O, Thilaganathan B, Thomson N, Visintin C, et al (2022). The impact of ultrasound-based antenatal screening strategies to detect vasa praevia in the United Kingdom: an exploratory study using decision analytic modelling methods. PLoS One, 17(12). Abstract. Author URL.
Taylor-Phillips S, Seedat F, Kijauskaite G, Marshall J, Halligan S, Hyde C, Given-Wilson R, Wilkinson L, Denniston AK, Glocker B, et al (2022). UK National Screening Committee's approach to reviewing evidence on artificial intelligence in breast cancer screening. Lancet Digit Health, 4(7), e558-e565. Abstract. Author URL.
Hajibandeh S, Hajibandeh S, Marshall MJ, Smart NJ, Winyard PG, Hyde C, Shaw AM, Daniels IR (2021). Biomarkers for diagnosis of acute appendicitis in adults. Cochrane Database of Systematic Reviews, 2021(10). Abstract.
Binney N, Hyde C, Bossuyt PM (2021). On the Origin of Sensitivity and Specificity. Annals of Internal Medicine, 174(3), 401-407.
Kokkinou M, Beishon LC, Smailagic N, Noel-Storr AH, Hyde C, Ukoumunne O, Worrall RE, Hayen A, Desai M, Ashok AH, et al (2021). Plasma and cerebrospinal fluid ABeta42 for the differential diagnosis of Alzheimer's disease dementia in participants diagnosed with any dementia subtype in a specialist care setting. Cochrane Database Syst Rev, 2(2). Abstract. Author URL.
Cohen JF, Deeks JJ, Hooft L, Salameh J-P, Korevaar DA, Gatsonis C, Hopewell S, Hunt HA, Hyde CJ, Leeflang MM, et al (2021). Preferred reporting items for journal and conference abstracts of systematic reviews and meta-analyses of diagnostic test accuracy studies (PRISMA-DTA for Abstracts): checklist, explanation, and elaboration. BMJ, 372 Abstract. Author URL.
Yang B, Mallett S, Takwoingi Y, Davenport CF, Hyde CJ, Whiting PF, Deeks JJ, Leeflang MMG (2021). QUADAS-C: a Tool for Assessing Risk of Bias in Comparative Diagnostic Accuracy Studies. Annals of Internal Medicine, 174(11), 1592-1599.
Lawday S, Flamey N, Fowler GE, Leaning M, Dyar N, Daniels IR, Smart NJ, Hyde C (2021). Quality of life in restorative versus non-restorative resections for rectal cancer: systematic review. BJS Open, 5(6). Abstract. Author URL.
Yang B, Olsen M, Vali Y, Langendam MW, Takwoingi Y, Hyde CJ, Bossuyt PMM, Leeflang MMG (2021). Study designs for comparative diagnostic test accuracy: a methodological review and classification scheme. J Clin Epidemiol, 138, 128-138. Abstract. Author URL.
Thompson G, Zhelev Z, Peters J, Khalid S, Briscoe S, Shaw L, Nunns M, Ludman S, Hyde C (2021). Symptom scores in the diagnosis of pediatric cow's milk protein allergy: a systematic review. Pediatr Allergy Immunol, 32(7), 1497-1507. Abstract. Author URL.
Cree IA, Indave Ruiz BI, Zavadil J, McKay J, Olivier M, Kozlakidis Z, Lazar AJ, Hyde C, Holdenrieder S, Hastings R, et al (2021). The International Collaboration for Cancer Classification and Research. Int J Cancer, 148(3), 560-571. Abstract. Author URL.
Peters J, Snowsill T, Griffin E, Robinson S, Hyde C (2021). Variation in Model-Based Economic Evaluations of Low Dose Computed Tomography (LDCT) Screening for Lung Cancer: a Methodological Review. Value in Health
Hyde C (2021). Will better evidence on clinical utility bring about greater use of (genetic) tests?. npj Genomic Medicine, 6(1).
Bossuyt PM, Olsen M, Hyde C, Cohen JF (2020). An analysis reveals differences between pragmatic and explanatory diagnostic accuracy studies. J Clin Epidemiol, 117, 29-35. Abstract. Author URL.
Mallett S, Allen AJ, Graziadio S, Taylor SA, Sakai NS, Green K, Suklan J, Hyde C, Shinkins B, Zhelev Z, et al (2020). At what times during infection is SARS-CoV-2 detectable and no longer detectable using RT-PCR-based tests? a systematic review of individual participant data. BMC Medicine, 18(1). Abstract.
Grigore B, Lewis R, Peters J, Robinson S, Hyde CJ (2020). Development, validation and effectiveness of diagnostic prediction tools for colorectal cancer in primary care: a systematic review. BMC Cancer, 20(1). Abstract.
Uttley L, Indave BI, Hyde C, White V, Lokuhetty D, Cree I (2020). Invited commentary-WHO Classification of Tumours: How should tumors be classified? Expert consensus, systematic reviews or both?. Int J Cancer, 146(12), 3516-3521. Author URL.
Griffin E, Hyde C, Long L, Varley-Campbell J, Coelho H, Robinson S, Snowsill T (2020). LUNG CANCER SCREENING BY LOW-DOSE COMPUTERISED TOMOGRAPHY: a COST EFFECTIVENESS ANALYSIS OF ALTERNATIVE PROGRAMMES IN THE UNITED KINGDOM USING a NEWLY DEVELOPED NATURAL HISTORY BASED ECONOMIC MODEL. VALUE IN HEALTH, 23, S66-S66. Author URL.
Griffin E, Hyde C, Long L, Varley-Campbell J, Coelho H, Robinson S, Snowsill T (2020). Lung cancer screening by low-dose computed tomography: a cost-effectiveness analysis of alternative programmes in the UK using a newly developed natural history-based economic model. Diagnostic and Prognostic Research, 4(1). Abstract.
Takwoingi Y, Partlett C, Riley RD, Hyde C, Deeks JJ (2020). Methods and reporting of systematic reviews of comparative accuracy were deficient: a methodological survey and proposed guidance. J Clin Epidemiol, 121, 1-14. Abstract. Author URL.
Griffin E, Hyde C, Long L, Varley-Campbell J, Coelho H, Robinson S, Snowsill T (2020). PCN248 LUNG CANCER SCREENING BY LOW-DOSE COMPUTERISED TOMOGRAPHY: a COST EFFECTIVENESS ANALYSIS OF ALTERNATIVE PROGRAMMES IN THE UNITED KINGDOM USING a NEWLY DEVELOPED NATURAL HISTORY BASED ECONOMIC MODEL. Value in Health, 23
Salameh JP, Bossuyt PM, McGrath TA, Thombs BD, Hyde CJ, MacAskill P, Deeks JJ, Leeflang M, Korevaar DA, Whiting P, et al (2020). Preferred reporting items for systematic review and meta-analysis of diagnostic test accuracy studies (PRISMA-DTA): Explanation, elaboration, and checklist. The BMJ, 370(12). Abstract.
Shaw AM, Hyde C, Merrick B, James-Pemberton P, Squires BK, Olkhov RV, Batra R, Patel A, Bisnauthsing K, Nebbia G, et al (2020). Real-world evaluation of a novel technology for quantitative simultaneous antibody detection against multiple SARS-CoV-2 antigens in a cohort of patients presenting with COVID-19 syndrome. Analyst, 145(16), 5638-5646. Abstract. Author URL.
McGovern AP, Hogg M, Shields BM, Sattar NA, Holman RR, Pearson ER, Hattersley AT, Jones AG, Dennis JM (2020). Risk factors for genital infections in people initiating SGLT2 inhibitors and their impact on discontinuation. BMJ Open Diabetes Research & Care, 8(1), e001238-e001238. Abstract.
Yang B, Vali Y, Dehmoobad Sharifabadi A, Harris IM, Beese S, Davenport C, Hyde C, Takwoingi Y, Whiting P, Langendam MW, et al (2020). Risk of bias assessment of test comparisons was uncommon in comparative accuracy systematic reviews: an overview of reviews. J Clin Epidemiol, 127, 167-174. Abstract. Author URL.
Reader P, Shaw A, Hyde C, Olkhov R (2019). A rapid and quantitative technique for assessing IgG monomeric purity, calibrated with the NISTmAb reference material. Analytical and Bioanalytical Chemistry
Snowsill TM, Ryan NAJ, Crosbie EJ, Frayling IM, Evans DG, Hyde CJ (2019). Cost-effectiveness analysis of reflex testing for Lynch syndrome in women with endometrial cancer in the UK setting. PLoS ONE
Yang H, Varley-Campbell J, Coelho H, Long L, Robinson S, Snowsill T, Griffin E, Peters J, Hyde C (2019). Do we know enough about the effect of low-dose computed tomography screening for lung cancer on survival to act? a systematic review, meta-analysis and network meta-analysis of randomised controlled trials. Diagnostic and Prognostic Research, 3(1). Abstract.
Varley-Campbell J, Cooper C, Coelho H, Dodman S, Barnish M, Mujica-Mota R, Hyde C, Hoyle M (2019). OP136 Full Texts Versus Conference Abstract Data: How Does the Message Change?. International Journal of Technology Assessment in Health Care, 34(S1), 50-51.
Wolff RF, Moons KGM, Riley RD, Whiting PF, Westwood M, Collins GS, Reitsma JB, Kleijnen J, Mallett S, Altman D, et al (2019). PROBAST: a Tool to Assess the Risk of Bias and Applicability of Prediction Model Studies. ANNALS OF INTERNAL MEDICINE, 170(1), 51-+. Author URL.
Varley-Campbell J, Mujica Mota R, Coelho H, Ocean N, Barnish M, Packman D, Dodman S, Cooper C, Snowsill TM, Kay T, et al (2019). Three biomarker tests to help diagnose preterm labour: a systematic review and economic evaluation. Health Technology Assessment, 23(13).
Olsen M, Zhelev Z, Hunt H, Peters JL, Bossuyt P, Hyde C (2019). Use of test accuracy study design labels in NICE's diagnostic guidance. Diagn Progn Res, 3 Abstract. Author URL.
Smailagic N, Lafortune L, Kelly S, Hyde C, Brayne C (2018). 18F-FDG PET for Prediction of Conversion to Alzheimer's Disease Dementia in People with Mild Cognitive Impairment: an Updated Systematic Review of Test Accuracy. J Alzheimers Dis, 64(4), 1175-1194. Abstract. Author URL.
Shepherd MH, Shields BM, Hudson M, Pearson ER, Hyde C, Ellard S, Hattersley AT, Patel KA, UNITED study (2018). A UK nationwide prospective study of treatment change in MODY: genetic subtype and clinical characteristics predict optimal glycaemic control after discontinuing insulin and metformin. Diabetologia, 61(12), 2520-2527. Abstract. Author URL.
Pang CL, Pilkington N, Wei Y, Peters J, Roobottom C, Hyde C (2018). A methodology review on the incremental prognostic value of computed tomography biomarkers in addition to Framingham risk score in predicting cardiovascular disease: the use of association, discrimination and reclassification. BMC Cardiovascular Disorders, 18
Castro R, Crathorne L, Perazzo H, Silva J, Cooper C, Varley-Campbell J, Marinho DS, Haasova M, Veloso VG, Anderson R, et al (2018). Cost-effectiveness of diagnostic and therapeutic interventions for chronic hepatitis C: a systematic review of model-based analyses. BMC Med Res Methodol, 18(1). Abstract. Author URL.
Walker GJ, Moore L, Heerasing N, Hendy P, Perry MH, McDonald TJ, Debenham T, Bethune R, Bewshea C, Hyde C, et al (2018). Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study. Aliment Pharmacol Ther, 47(8), 1103-1116. Abstract. Author URL.
McInnes MDF, Moher D, Thombs BD, McGrath TA, Bossuyt PM, and the PRISMA-DTA Group, Clifford T, Cohen JF, Deeks JJ, Gatsonis C, et al (2018). Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies: the PRISMA-DTA Statement. JAMA, 319(4), 388-396. Abstract. Author URL.
Chisnell J, Marshall T, Hyde C, Zhelev Z, Fleming LE (2017). A content analysis of the representation of statins in the British newsprint media. BMJ Open, 7(8). Abstract. Author URL.
Coelho H, Jones-Hughes T, Snowsill T, Briscoe S, Huxley N, Frayling IM, Hyde C (2017). A systematic review of test accuracy studies evaluating molecular micro-satellite instability testing for the detection of individuals with lynch syndrome. BMC Cancer, 17(1). Abstract. Author URL.
Perazzo H, Pacheco AG, Luz PM, Castro R, Hyde C, Fittipaldi J, Rigolon C, Cardoso SW, Grinsztejn B, Veloso VG, et al (2017). Age-standardized mortality rates related to viral hepatitis in Brazil. BMC Infect Dis, 17(1). Abstract. Author URL.
Grigore B, Peters J, Hyde C, Stein K (2017). EXPLICIT: a feasibility study of remote expert elicitation in health technology assessment. BMC Med Inform Decis Mak, 17(1). Abstract. Author URL.
Gopalakrishna G, Langendam M, Scholten R, Bossuyt P, Leeflang M, Noel-Storr A, Thomas J, Marshall I, Wallace B, Whiting P, et al (2017). Erratum to: Methods for evaluating medical tests and biomarkers. Diagn Progn Res, 1 Abstract. Author URL.
Tenant S, Pang CL, Dissanayake P, Vardhanabhuti V, Stuckey C, Gutteridge C, Hyde C, Roobottom C (2017). Intra-patient comparison of reduced-dose model-based iterative reconstruction with standard-dose adaptive statistical iterative reconstruction in the CT diagnosis and follow-up of urolithiasis. Eur Radiol, 27(10), 4163-4172. Abstract. Author URL.
Perazzo H, Jorge MJ, Silva JC, Avellar AM, Silva PS, Romero C, Veloso VG, Mujica-Mota R, Anderson R, Hyde C, et al (2017). Micro-costing analysis of guideline-based treatment by direct-acting agents: the real-life case of hepatitis C management in Brazil. BMC Gastroenterol, 17(1). Abstract. Author URL.
Snowsill T, Coelho H, Huxley N, Jones-Hughes T, Briscoe S, Frayling IM, Hyde C (2017). Molecular testing for Lynch syndrome in people with colorectal cancer: systematic reviews and economic evaluation. Health Technol Assess, 21(51), 1-238. Abstract. Author URL.
Shields B, Shepherd M, Hudson M, McDonald T, Colclough K, Peters J, Knight B, Hyde C, Ellard S, Pearson E, et al (2017). Population-based assessment of a biomarker-based screening pathway to aid diagnosis of monogenic diabetes in young-onset patients. Diabetes Care
Vardhanabhuti V, Pang CL, Tenant S, Taylor J, Hyde C, Roobottom C (2017). Prospective intra-individual comparison of standard dose versus reduced-dose thoracic CT using hybrid and pure iterative reconstruction in a follow-up cohort of pulmonary nodules—Effect of detectability of pulmonary nodules with lowering dose based on nodule size, type and body mass index. European Journal of Radiology, 91, 130-141. Abstract.
Ferrante di Ruffano L, Dinnes J, Taylor-Phillips S, Davenport C, Hyde C, Deeks JJ (2017). Research waste in diagnostic trials: a methods review evaluating the reporting of test-treatment interventions. BMC Med Res Methodol, 17(1). Abstract. Author URL.
Cohen JF, Korevaar DA, Gatsonis CA, Glasziou PP, Hooft L, Moher D, Reitsma JB, De Vet HCW, Bossuyt PM, Alonzo T, et al (2017). STARD for Abstracts: Essential items for reporting diagnostic accuracy studies in journal or conference abstracts. BMJ (Online), 358 Abstract.
van Giessen A, Peters J, Wilcher B, Hyde C, Moons C, de Wit A, Koffijberg E (2017). Systematic Review of Health Economic Impact Evaluations of Risk Prediction Models: Stop Developing, Start Evaluating. Value in Health, 20(4), 718-726. Abstract.
Ferrante di Ruffano L, Dinnes J, Sitch AJ, Hyde C, Deeks JJ (2017). Test-treatment RCTs are susceptible to bias: a review of the methodological quality of randomized trials that evaluate diagnostic tests. BMC Med Res Methodol, 17(1). Abstract. Author URL.
Hunt HA, Van Kampen S, Takwoingi Y, Llewellyn DJ, Pearson M, Hyde CJ (2017). The comparative diagnostic accuracy of the Mini Mental State Examination (MMSE) and the General Practitioner assessment of Cognition (GPCOG) for identifying dementia in primary care: a systematic review protocol. Diagnostic and Prognostic Research, 1, 1-6.
Grigore B, Peters J, Hyde C, Stein K (2016). A comparison of two methods for expert elicitation in health technology assessments. BMC Med Res Methodol, 16 Abstract. Author URL.
Fortnum H, Ukoumunne OC, Hyde C, Taylor RS, Ozolins M, Errington S, Zhelev Z, Pritchard C, Benton C, Moody J, et al (2016). A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes. Health Technol Assess, 20(36), 1-178. Abstract. Author URL.
Jennison C, Jobling A, Pearson E, Hattersley A, Gray A, Hyde C (2016). Assessing the benefits of a stratified treatment strategy which improves average HbA1c in a proportion of patients with Type 2 diabetes: a MASTERMIND study. DIABETIC MEDICINE, 33, 23-23. Author URL.
Iyengar SS, Morgan-Hughes G, Ukoumunne O, Clayton B, Davies EJ, Nikolaou V, Hyde CJ, Shore AC, Roobottom CA (2016). Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients. Clin Radiol, 71(2), 151-158. Abstract. Author URL.
Zhelev Z, Abbott R, Rogers M, Fleming S, Patterson A, Hamilton WT, Heaton J, Thompson Coon J, Vaidya B, Hyde C, et al (2016). Effectiveness of interventions to reduce ordering of thyroid function tests: a systematic review. BMJ Open, 6(6). Abstract. Author URL.
Bond M, Crathorne L, Peters J, Coelho H, Haasova M, Cooper C, Milner Q, Shawyer V, Hyde C, Powell R, et al (2016). First do no harm: pain relief for the peripheral venous cannulation of adults, a systematic review and network meta-analysis. BMC Anesthesiol, 16(1). Abstract. Author URL.
Haasova M, Snowsill T, Jones-Hughes T, Crathorne L, Cooper C, Varley-Campbell J, Mujica-Mota R, Coelho H, Huxley N, Lowe J, et al (2016). Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation. Health Technol Assess, 20(61), 1-324. Abstract. Author URL.
Hyde C, Fortnum H, Ukoumunne O, Ozlin M, Zhelev Z, Long L (2016). P107 Evaluation of school entry hearing screening: findings of an NIHR funded project. Journal of Epidemiology & Community Health, 70(Suppl 1).
Shepherd M, Shields B, Hammersley S, Hudson M, McDonald TJ, Colclough K, Oram RA, Knight B, Hyde C, Cox J, et al (2016). Systematic Population Screening, Using Biomarkers and Genetic Testing, Identifies 2.5% of the U.K. Pediatric Diabetes Population with Monogenic Diabetes. Diabetes Care, 39(11), 1879-1888. Abstract. Author URL.
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long L, Medina-Lara A, et al (2016). The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer-treatment induced anaemia (including review of TA142): a systematic review and economic model. Health Technology Assessment Author URL.
Smailagic N, Vacante M, Hyde C, Martin S, Ukoumunne O, Sachpekidis C (2015). <SUP>18</SUP>F-FDG PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). COCHRANE DATABASE OF SYSTEMATIC REVIEWS(1). Author URL.
Bond M, Garside R, Hyde C (2015). A crisis of visibility: the psychological consequences of false-positive screening mammograms, an interview study. British Journal of Health Psychology, 20(4), 792-806. Abstract.
Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2015). A model-based assessment of the cost-utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients. BMC Cancer, 15 Abstract. Author URL.
Huxley N, Jones-Hughes T, Coelho H, Snowsill T, Cooper C, Meng Y, Hyde C, Mújica-Mota R (2015). A systematic review and economic evaluation of intraoperative tests [RD-100i one-step nucleic acid amplification (OSNA) system and Metasin test] for detecting sentinel lymph node metastases in breast cancer. Health Technol Assess, 19(2), v-215. Abstract. Author URL.
Marshall MJ, Smart NJ, Hyde C, Winyard PG, Shaw AM, Daniels IR (2015). Biomarkers for diagnosis of acute appendicitis in adults. COCHRANE DATABASE OF SYSTEMATIC REVIEWS(3). Author URL.
Shields BM, Peters JL, Cooper C, Lowe J, Knight BA, Powell RJ, Jones A, Hyde CJ, Hattersley AT (2015). Can clinical features be used to differentiate type 1 from type 2 diabetes? a systematic review of the literature. BMJ Open, 5(11). Abstract. Author URL.
Castro R, Perazzo H, Grinsztejn B, Veloso VG, Hyde C (2015). Chronic Hepatitis C: an Overview of Evidence on Epidemiology and Management from a Brazilian Perspective. Int J Hepatol, 2015 Abstract. Author URL.
Zhelev Z, Hyde C, Youngman E, Rogers M, Fleming S, Slade T, Coelho H, Jones-Hughes T, Nikolaou V (2015). Diagnostic accuracy of single baseline measurement of Elecsys Troponin T high-sensitive assay for diagnosis of acute myocardial infarction in emergency department: systematic review and meta-analysis. BMJ, 350 Abstract. Author URL.
McCleery J, Morgan S, Bradley KM, Noel-Storr AH, Ansorge O, Hyde C (2015). Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies. COCHRANE DATABASE OF SYSTEMATIC REVIEWS(1). Author URL.
Perazzo H, Veloso VG, Grinsztejn B, Hyde C, Castro R (2015). Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography. Int J Hepatol, 2015 Abstract. Author URL.
Whiting PF, Davenport C, Jameson C, Burke M, Sterne JAC, Hyde C, Ben-Shlomo Y (2015). How well do health professionals interpret diagnostic information? a systematic review. BMJ Open, 5(7). Abstract. Author URL.
Bond M, Garside R, Hyde C (2015). Improving screening recall services for women with false-positive mammograms: a comparison of qualitative evidence with UK guidelines. BMJ Open, 5(1). Abstract. Author URL.
Vardhanabhuti V, James J, Nensey R, Hyde C, Roobottom C (2015). Model-based iterative reconstruction in low-dose CT colonography-feasibility study in 65 patients for symptomatic investigation. Academic Radiology, 22(5), 563-571. Abstract.
Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig L, Lijmer JG, Moher D, Rennie D, De Vet HCW, et al (2015). STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. Clinical Chemistry, 61(12), 1446-1452. Abstract.
Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig L, Lijmer JG, Moher D, Rennie D, de Vet HCW, et al (2015). STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ-BRITISH MEDICAL JOURNAL, 351 Author URL.
Zhelev Z, Hyde C, Fitzgerald JE, Ukoumunne O, Briscoe S, Chisnell J, Grigore B (2015). Tests for screening for hearing loss in children about to start school. Cochrane Database of Systematic Reviews, 2015(11). Abstract.
Hunt HA, Stanworth S, Curry N, Wolley T, Cooper C, Ukoumunne O, Zhelev Z, Hyde C (2015). Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma-induced coagulopathy in adult trauma patients with bleeding. Cochrane Database of Systematic Reviews 2015(2).
Long L, Briscoe S, Cooper C, Hyde C, Crathorne L (2015). What is the clinical effectiveness and cost-effectiveness of conservative interventions for tendinopathy? an overview of systematic reviews of clinical effectiveness and systematic review of economic evaluations. Health Technology Assessment, 19(8), 5-73. Abstract.
Willis BH, Hyde CJ (2015). What is the test's accuracy in my practice population? Tailored meta-analysis provides a plausible estimate. J Clin Epidemiol, 68(8), 847-854. Abstract. Author URL.
Zhang S, Smailagic N, Hyde C, Noel-Storr AH, Takwoingi Y, McShane R, Feng J (2014). 11C-PIB-PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI). COCHRANE DATABASE OF SYSTEMATIC REVIEWS(7). Author URL.
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long L, Medina-Lara A, et al (2014). 1498PWHAT IS THE CLINICAL EFFECTIVENESS OF ERYTHROPOIESIS STIMULATING AGENTS FOR THE TREATMENT OF CANCER TREATMENT-INDUCED ANAEMIA?. Ann Oncol, 25(suppl_4), iv523-iv524. Author URL.
Haasova M, Crathorne L, Huxley N, Hyde C (2014). 1502PWHAT IS THE CLINICAL AND COST EFFECTIVENESS OF ERYTHROPOIETIN-STIMULATING AGENTS FOR THE TREATMENT OF PATIENTS WITH CANCER-TREATMENT INDUCED ANAEMIA? INSIGHTS FROM CUMULATIVE META-ANALYSES (CMA) AND LESSONS FOR COST-EFFECTIVENESS ANALYSES. Ann Oncol, 25(suppl_4). Author URL.
Snowsill T, Huxley N, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2014). A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome. Health Technology Assessment, 18(58). Author URL.
Gopalakrishna G, Mustafa RA, Davenport C, Scholten RJPM, Hyde C, Brozek J, Schünemann HJ, Bossuyt PMM, Leeflang MMG, Langendam MW, et al (2014). Applying Grading of Recommendations Assessment, Development and Evaluation (GRADE) to diagnostic tests was challenging but doable. Journal of Clinical Epidemiology, 67(7), 760-768. Abstract.
Willis BH, Hyde CJ (2014). Estimating a test's accuracy using tailored meta-analysis-How setting-specific data may aid study selection. J Clin Epidemiol, 67(5), 538-546. Abstract. Author URL.
Jones AG, Shields BM, Hyde CJ, Henley WE, Hattersley AT (2014). Identifying good responders to glucose lowering therapy in type 2 diabetes: implications for stratified medicine. PLoS One, 9(10). Abstract. Author URL.
Vardhanabhuti V, Riordan RD, Mitchell GR, Hyde C, Roobottom CA (2014). Image comparative assessment using iterative reconstructions: clinical comparison of low-dose abdominal/pelvic computed tomography between adaptive statistical, model-based iterative reconstructions and traditional filtered back projection in 65 patients. Invest Radiol, 49(4), 209-216. Abstract. Author URL.
Kokkinou M, Smailagic N, Noel-Storr AH, Hyde C, Ukoumunne O, Worrall RE, Hayen A, Desai M, Ritchie C (2014). Plasma and Cerebrospinal fluid (CSF) Abeta42 for the differential diagnosis of Alzheimer's disease dementia in participants diagnosed with any dementia subtype in a specialist care setting. Cochrane Database of Systematic Reviews, 2014(1). Abstract.
Noel-Storr AH, McCleery JM, Richard E, Ritchie CW, Flicker L, Cullum SJ, Davis D, Quinn TJ, Hyde C, Rutjes AWS, et al (2014). Reporting standards for studies of diagnostic test accuracy in dementia: the STARDdem Initiative. Neurology, 83(4), 364-373. Abstract.
Walker S, Hyde C, Hamilton W (2014). Risk of breast cancer in symptomatic women in primary care: a case-control study using electronic records. Br J Gen Pract, 64(629), e788-e793. Abstract. Author URL.
Zhang S, Smailagic N, Hyde C, Han D, Noel-Storr A, Takwoingi Y, Mcshane R (2013). <sup>11</sup>C-PIB-PET for the early diagnosis of Alzheimers disease dementia and other dementias in people with mild cognitive impairment (MCI). Cochrane Database of Systematic Reviews, 2013(2). Abstract.
Zhelev Z, Garside R, Hyde C (2013). A qualitative study into the difficulties experienced by healthcare decision makers when reading a Cochrane diagnostic test accuracy review. Syst Rev, 2 Abstract. Author URL.
Hopewell S, Omar O, Hyde C, Yu LM, Doree C, Murphy MF (2013). A systematic review of the effect of red blood cell transfusion on mortality: Evidence from large-scale observational studies published between 2006 and 2010. BMJ Open, 3(5). Abstract.
Hoyle M, Peters J, Crathorne L, Jones-Hughes T, Cooper C, Napier M, Hyde C (2013). Cost-effectiveness of cetuximab, cetuximab plus irinotecan, and panitumumab for third and further lines of treatment for KRAS wild-type patients with metastatic colorectal cancer. Value Health, 16(2), 288-296. Abstract. Author URL.
Peters JL, Anderson R, Hyde C (2013). Development of an economic evaluation of diagnostic strategies: the case of monogenic diabetes. BMJ Open, 3(5). Abstract.
Hyde C, Thornton S (2013). Does screening for pre-eclampsia make sense?. BJOG, 120(10), 1168-1170. Author URL.
Mccleery J, Morgan S, Hyde C, Bradley K, Ansorge O (2013). Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies. Cochrane Database of Systematic Reviews, 2013(7). Abstract.
Peters JL, Anderson R, Hoyle M, Hyde C (2013). Evolution of a cost-utility model of donepezil for Alzheimer's disease. Int J Technol Assess Health Care, 29(2), 147-154. Abstract. Author URL.
Hyde C, Peters J, Bond M, Rogers G, Hoyle M, Anderson R, Jeffreys M, Davis S, Thokala P, Moxham T, et al (2013). Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: systematic review and economic model. Age Ageing, 42(1), 14-20. Abstract. Author URL.
Grigore B, Peters J, Hyde C, Stein K (2013). Methods to elicit probability distributions from experts: a systematic review of reported practice in health technology assessment. Pharmacoeconomics, 31(11), 991-1003. Abstract. Author URL.
Davis DH, Creavin ST, Noel-Storr A, Quinn TJ, Smailagic N, Hyde C, Brayne C, McShane R, Cullum S (2013). Neuropsychological tests for the diagnosis of Alzheimer's disease dementia and other dementias: a generic protocol for cross-sectional and delayed-verification studies. Cochrane Database Syst Rev(3). Abstract. Author URL.
Bond M, Pavey T, Welch K, Cooper C, Garside R, Dean S, Hyde CJ (2013). Psychological consequences of false-positive screening mammograms in the UK. Evid Based Med, 18(2), 54-61. Abstract. Author URL.
Walker S, Hyde C, Hamilton W (2013). Risk of uterine cancer in symptomatic women in primary care: case-control study using electronic records. Br J Gen Pract, 63(614), e643-e648. Abstract. Author URL.
Noel-Storr AH, Flicker L, Ritchie CW, Nguyen GH, Gupta T, Wood P, Walton J, Desai M, Solomon DF, Molena E, et al (2013). Systematic review of the body of evidence for the use of biomarkers in the diagnosis of dementia. Alzheimer's and Dementia, 9(3). Abstract.
Bond M, Pavey T, Welch K, Cooper C, Garside R, Dean S, Hyde C (2013). Systematic review of the psychological consequences of false-positive screening mammograms. Health Technology Assessment, 17, 1-86. Abstract. Author URL.
Vacante M, Smailagic N, Sachpekidis C, Hyde C, Martin S, Ukoumunne O (2013). The accuracy of <sup>18</sup>FDG-PET in the early diagnosis of Alzheimer's disease dementia and other dementias in people with MCI. Cochrane Database of Systematic Reviews, 2013(7). Abstract.
Hoyle M, Crathorne L, Peters J, Jones-Hughes T, Cooper C, Napier M, Tappenden P, Hyde C (2013). The clinical effectiveness and cost-effectiveness of cetuximab (mono- or combination chemotherapy), bevacizumab (combination with non-oxaliplatin chemotherapy) and panitumumab (monotherapy) for the treatment of metastatic colorectal cancer after first-line chemotherapy (review of technology appraisal No.150 and part review of technology appraisal No. 118): a systematic review and economic model. Health Technol Assess, 17(14), 1-237. Abstract. Author URL.
Hunt HA, Hyde CJ, Stanworth S, Curry N, Perel P, Woolley T, Cooper C, Ukoumunne O (2013). Thromboelastography (TEG) and thromboelastometry (ROTEM) for trauma-induced coagulopathy in adult trauma patients with bleeding [Protocol]. Cochrane Database of Systematic Reviews 2013
Vaidya B, Ukoumunne OC, Shuttleworth J, Bromley A, Lewis A, Hyde C, Patterson A, Fleming S, Tomlinson J (2013). Variability in thyroid function test requests across general practices in south-west England. Qual Prim Care, 21(3), 143-148. Abstract. Author URL.
Long HL, Briscoe S, Cooper C, Hyde C, Crathrone L (2013). What is the effectiveness and cost-effectiveness of conservative interventions for tendinopathy: an overview of systematic reviews of clinical effectiveness and systematic review of economic evaluations.
Ferrante di Ruffano L, Davenport C, Eisinga A, Hyde C, Deeks JJ (2012). A capture-recapture analysis demonstrated that randomized controlled trials evaluating the impact of diagnostic tests on patient outcomes are rare. J Clin Epidemiol, 65(3), 282-287. Abstract. Author URL.
Islam R, Tinmouth AT, Francis JJ, Brehaut JC, Born J, Stockton C, Stanworth SJ, Eccles MP, Cuthbertson BH, Hyde C, et al (2012). A cross-country comparison of intensive care physicians' beliefs about their transfusion behaviour: a qualitative study using the theoretical domains framework. Implementation Science, 7(1). Abstract.
Ferrante di Ruffano L, Hyde CJ, McCaffery KJ, Bossuyt PMM, Deeks JJ (2012). Assessing the value of diagnostic tests: a framework for designing and evaluating trials. BMJ, 344 Author URL.
Tonia T, Mettler A, Robert N, Schwarzer G, Seidenfeld J, Weingart O, Hyde C, Engert A, Bohlius J (2012). Erythropoietin or darbepoetin for patients with cancer. COCHRANE DATABASE OF SYSTEMATIC REVIEWS(12). Author URL.
Shields BM, Peters JL, Cooper C, Powell RJ, Knight BA, Hyde C, Hattersley AT (2012). Identifying clinical criteria to predict Type 1 diabetes, as defined by absolute insulin deficiency: a systematic review protocol. BMJ Open, 2(6). Abstract. Author URL.
Honest H, Hyde CJ, Khan KS (2012). Prediction of spontaneous preterm birth: no good test for predicting a spontaneous preterm birth. Curr Opin Obstet Gynecol, 24(6), 422-433. Abstract. Author URL.
Noel-Storr AH, Flicker L, Ritchie CW, Nguyen GH, Gupta T, Wood P, Walton J, Desai M, Solomon DF, Molena E, et al (2012). Systematic review of the body of evidence for the use of biomarkers in the diagnosis of dementia. Alzheimer's and Dementia
Shields BM, McDonald TJ, Ellard S, Campbell MJ, Hyde C, Hattersley AT (2012). The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes. Diabetologia, 55(5), 1265-1272. Abstract. Author URL.
Bond M, Rogers G, Peters J, Anderson R, Hoyle M, Miners A, Moxham T, Davis S, Thokala P, Wailoo A, et al (2012). The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model. Health Technol Assess, 16(21), 1-470. Abstract. Author URL.
Auguste P, Barton P, Hyde C, Roberts TE (2011). An economic evaluation of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence. Health Technol Assess, 15(18), iii-54. Abstract. Author URL.
Connock M, Hyde C, Moore D (2011). Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer. Pharmacoeconomics, 29(10), 827-837. Abstract. Author URL.
Hoyle M, Crathorne L, Garside R, Hyde C (2011). Ofatumumab for the treatment of chronic lymphocytic leukaemia in patients who are refractory to fludarabine and alemtuzumab: a critique of the submission from GSK. Health Technol Assess, 15 Suppl 1, 61-67. Abstract. Author URL.
Horsley T, Hyde C, Santesso N, Parkes J, Milne R, Stewart R (2011). Teaching critical appraisal skills in healthcare settings. COCHRANE DATABASE OF SYSTEMATIC REVIEWS(11). Author URL.
Wilkinson KL, Brunskill SJ, Dorée C, Hopewell S, Stanworth S, Murphy MF, Hyde C (2011). The Clinical Effects of Red Blood Cell Transfusions: an Overview of the Randomized Controlled Trials Evidence Base. Transfusion Medicine Reviews, 25(2). Abstract.
Curry N, Hopewell S, Dorée C, Hyde C, Brohi K, Stanworth S (2011). The acute management of trauma hemorrhage: a systematic review of randomized controlled trials. Critical Care, 15(2). Abstract.
Curry N, Stanworth S, Hopewell S, Dorée C, Brohi K, Hyde C (2011). Trauma-induced coagulopathy-A review of the systematic reviews: is there sufficient evidence to guide clinical transfusion practice?. Transfusion Medicine Reviews, 25(3). Abstract.
Lin Y, Stanworth S, Birchall J, Doree C, Hyde C (2011). Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: a systematic review and meta-analysis. CMAJ. Canadian Medical Association Journal, 183(1). Abstract.
Pennant M, Takwoingi Y, Pennant L, Davenport C, Fry-Smith A, Eisinga A, Andronis L, Arvanitis T, Deeks J, Hyde C, et al (2010). A systematic review of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence. Health Technol Assess, 14(50), 1-103. Abstract. Author URL.
Cnossen JS, Riet GT, Mol BW, van der Post JA, Leeflang MM, Meads CA, Hyde C, Khan KS (2010). Are Tests for Predicting Preeclampsia Good Enough to Make Screening Viable? a Review of Reviews and Critical Appraisal. Obstetric Anesthesia Digest, 30(1), 13-14.
Edlin R, Connock M, Tubeuf S, Round J, Fry-Smith A, Hyde C, Greenheld W (2010). Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia. Health Technology Assessment, 14(Suppl 1 Article 10), 69-74.
Edlin R, Connock M, Tubeuf S, Round J, Fry-Smith A, Hyde C, Greenheld W (2010). Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia. Health Technol Assess, 14 Suppl 1, 69-74. Abstract. Author URL.
Ashfaq K, Yahaya I, Hyde C, Andronis L, Barton P, Bayliss S, Chen Y-F (2010). Clinical effectiveness and cost-effectiveness of stem cell transplantation in the management of acute leukaemia: a systematic review. Health Technol Assess, 14(54), iii-141. Abstract. Author URL.
Pennant M, Davenport C, Bayliss S, Greenheld W, Marshall T, Hyde C (2010). Community programs for the prevention of cardiovascular disease: a systematic review. Am J Epidemiol, 172(5), 501-516. Abstract. Author URL.
Pitt M, Crathorne L, Moxham T, Bond M, Hyde C (2010). Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis. Health Technol Assess, 14(Suppl. 2), 41-46. Abstract.
Bryan S, Andronis L, Hyde C, Connock M, Fry-Smith A, Wang D (2010). Infliximab for the treatment of acute exacerbations of ulcerative colitis. Health Technology Assessment, 14(Suppl 1 Article 2), 9-15.
Bryan S, Andronis L, Hyde C, Connock M, Fry-Smith A, Wang D (2010). Infliximab for the treatment of acute exacerbations of ulcerative colitis. Health Technol Assess, 14 Suppl 1, 9-15. Abstract. Author URL.
Jairath V, Hearnshaw S, Brunskill SJ, Doree C, Hopewell S, Hyde C, Travis S, Murphy MF (2010). Red cell transfusion for the management of upper gastrointestinal haemorrhage. COCHRANE DATABASE OF SYSTEMATIC REVIEWS(9). Author URL.
Dorée C, Stanworth S, Brunskill SJ, Hopewell S, Hyde CJ, Murphy MF (2010). Where are the systematic reviews in transfusion medicine? a study of the transfusion evidence base. Transfusion Medicine Reviews, 24(4), 286-294. Abstract.
Tsourapas A, Roberts TE, Barton PM, Honest H, Forbes C, Hyde CJ, Khan KS (2009). An economic evaluation of alternative test-intervention strategies to prevent spontaneous pre-term birth in singleton pregnancies. Acta Obstet Gynecol Scand, 88(12), 1319-1330. Abstract. Author URL.
Cnossen JS, ter Riet G, Mol BW, van der Post JA, Leeflang MM, Meads CA, Hyde C, Khan KS (2009). Are tests for predicting pre-eclampsia good enough to make screening viable? a review of reviews and critical appraisal. Acta Obstet Gynecol Scand, 88(7), 758-765. Abstract. Author URL.
Siddiq S, Pamphilon D, Brunskill S, Doree C, Hyde C, Stanworth S (2009). Bone marrow harvest versus peripheral stem cell collection for haemopoietic stem cell donation in healthy donors. Cochrane Database Syst Rev(1). Abstract. Author URL.
Chen Y-F, Jowett S, Barton P, Malottki K, Hyde C, Gibbs JSR, Pepke-Zaba J, Fry-Smith A, Roberts J, Moore D, et al (2009). Clinical and cost-effectiveness of epoprostenol, iloprost, bosentan, sitaxentan and sildenafil for pulmonary arterial hypertension within their licensed indications: a systematic review and economic evaluation. Health Technol Assess, 13(49), 1-320. Abstract. Author URL.
Francis JJ, Stockton C, Eccles MP, Johnston M, Cuthbertson BH, Grimshaw JM, Hyde C, Tinmouth A, Stanworth SJ (2009). Evidence-based selection of theories for designing behaviour change interventions: using methods based on theoretical construct domains to understand clinicians' blood transfusion behaviour. Br J Health Psychol, 14(Pt 4), 625-646. Abstract. Author URL.
Stanworth SJ, Brunskill SJ, Hyde CJ, Murphy MF (2009). Evidence‐Based Use of Platelets1. Transfusion Alternatives in Transfusion Medicine, 8(1s), 31-31.
Wood EM, Stanworth S, Doree C, Hyde C, Silvani CM, Montedori A, Abraha I (2009). Fresh frozen plasma for cardiovascular surgery. Cochrane Database of Systematic Reviews(1).
Wood EM, Stanworth S, Doree C, Hyde CJ, Silvani CM, Montedori A, Abraha I (2009). Fresh frozen plasma for cardiovascular surgery (Protocol). Cochrane Database of Systematic Reviews(1).
Brunskill SJ, Hyde CJ, Stanworth SJ, Dorée CJ, Roberts DJ, Murphy MF (2009). Improving the evidence base for transfusion medicine: the work of the UK systematic review initiative. Transfus Med, 19(2), 59-65. Abstract. Author URL.
Hyde C, Bryan S, Juarez-Garcia A, Andronis L, Fry-Smith A (2009). Infliximab for the treatment of ulcerative colitis. Health Technology Assessment, 13(Suppl 3 Article 2), 7-12.
Hyde C, Bryan S, Juarez-Garcia A, Andronis L, Fry-Smith A (2009). Infliximab for the treatment of ulcerative colitis. Health Technol Assess, 13 Suppl 3, 7-11. Abstract. Author URL.
Wood P, UK Primary Immunodeficiency Network (2009). Primary antibody deficiencies: recognition, clinical diagnosis and referral of patients. Clin Med (Lond), 9(6), 595-599. Abstract. Author URL.
Board TN, Brunskill S, Doree C, Hyde C, Kay PR, Meek RD, Webster R, Galea G (2009). Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty. Cochrane Database Syst Rev, 2009(4). Abstract. Author URL.
Hearnshaw S, Brunskill S, Doree C, Hyde C, Travis S, Murphy MF (2009). Red cell transfusion for the management of upper gastrointestinal haemorrhage. Cochrane Database Syst Rev(2). Abstract. Author URL.
Silva MA, Hegab B, Hyde C, Guo B, Buckels JAC, Mirza DF (2009). Risk of seeding is reduced by associating diagnostic biopsy with percutaneous ablation for hepatocellular carcinoma Response. GUT, 58(5), 735-735. Author URL.
Brunskill SJ, Hyde CJ, Doree CJ, Watt SM, Martin-Rendon E (2009). Route of delivery and baseline left ventricular ejection fraction, key factors of bone-marrow-derived cell therapy for ischaemic heart disease. Eur J Heart Fail, 11(9), 887-896. Abstract. Author URL.
Honest H, Forbes CA, Durée KH, Norman G, Duffy SB, Tsourapas A, Roberts TE, Barton PM, Jowett SM, Hyde CJ, et al (2009). Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling. Health Technol Assess, 13(43), 1-627. Abstract. Author URL.
Pamphilon D, Siddiq S, Brunskill S, Dorée C, Hyde C, Horowitz M, Stanworth S (2009). Stem cell donation--what advice can be given to the donor?. Br J Haematol, 147(1), 71-76. Abstract. Author URL.
Martin-Rendon E, Brunskill S, Hyde C, Doree C, Mathur A, Taggart DP (2009). Stem cell therapy for ischaemic heart disease and congestive heart failure. Cochrane Database of Systematic Reviews(3).
Martin-Rendon E, Brunskill S, Hyde CJ, Doree C, Mathur A, Taggart DP (2009). Stem cell therapy for ischaemic heart disease and congestive heart failure (Protocol). Cochrane Database of Stematic Reviews(3).
Dretzke J, Davenport C, Frew E, Barlow J, Stewart-Brown S, Bayliss S, Taylor RS, Sandercock J, Hyde C (2009). The clinical effectiveness of different parenting programmes for children with conduct problems: a systematic review of randomised controlled trials. Child Adolesc Psychiatry Ment Health, 3(1). Abstract. Author URL.
Francis JJ, Tinmouth A, Stanworth SJ, Grimshaw JM, Johnston M, Hyde C, Stockton C, Brehaut JC, Fergusson D, Eccles MP, et al (2009). Using theories of behaviour to understand transfusion prescribing in three clinical contexts in two countries: development work for an implementation trial. Implement Sci, 4 Abstract. Author URL.
Wilson J, Yao GL, Raftery J, Bohlius J, Brunskill S, Sandercock J, Bayliss S, Moss P, Stanworth S, Hyde C, et al (2008). A systematic review and economic evaluation of epoetin alpha, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment. Pediatric Hematology/Oncology and Immunopathology, 7(2), 25-27.
Roberts J, Huissoon A, Dretzke J, Wang D, Hyde C (2008). A systematic review of the clinical effectiveness of acupuncture for allergic rhinitis. BMC Complement Altern Med, 8 Abstract. Author URL.
Martin-Rendon E, Brunskill SJ, Hyde CJ, Stanworth SJ, Mathur A, Watt SM (2008). Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review. Eur Heart J, 29(15), 1807-1818. Abstract. Author URL.
Hyde CJ, Stanworth SJ, Murphy MF (2008). Can you see the wood for the trees? Making sense of forest plots in systematic reviews 2. Analysis of the combined results from the included studies. Transfusion, 48(4), 580-583. Author URL.
Hyde CJ, Stanworth SJ, Murphy MF (2008). Can you see the wood for the trees? Making sense of forest plots in systematic reviews. Transfusion, 48(2), 218-220. Author URL.
Birchall J, Stanworth SJ, Duffy MR, Doree CJ, Hyde C (2008). Evidence for the use of recombinant factor VIIa in the prevention and treatment of bleeding in patients without hemophilia. Transfus Med Rev, 22(3), 177-187. Abstract. Author URL.
Meads CA, Cnossen JS, Meher S, Juarez-Garcia A, ter Riet G, Duley L, Roberts TE, Mol BW, van der Post JA, Leeflang MM, et al (2008). Methods of prediction and prevention of pre-eclampsia: systematic reviews of accuracy and effectiveness literature with economic modelling. Health Technol Assess, 12(6), iii-270. Abstract. Author URL.
Silva MA, Hegab B, Hyde C, Guo B, Buckels JAC, Mirza DF (2008). Needle track seeding following biopsy of liver lesions in the diagnosis of hepatocellular cancer: a systematic review and meta-analysis. Gut, 57(11), 1592-1596. Abstract. Author URL.
Martin-Rendon E, Brunskill S, Dorée C, Hyde C, Watt S, Mathur A, Stanworth S (2008). Stem cell treatment for acute myocardial infarction. Cochrane Database Syst Rev(4). Abstract. Author URL.
Wilson J, Yao GL, Raftery J, Bohlius J, Brunskill S, Sandercock J, Bayliss S, Moss P, Stanworth S, Hyde C, et al (2007). A systematic review and economic evaluation of epoetin alpha, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment. Health Technol Assess, 11(13), 1-iv. Abstract. Author URL.
Siddiq S, Brunskill S, Stanworth S, Doree C, Hyde C, Pamphilon D (2007). Bone marrow harvest versus peripheral stem cell collection for haemopoietic stem cell donation in healthy donors. Cochrane Database of Systematic Reviews(1).
Siddq S, Brunskill S, Stanworth S, Doree C, Hyde CJ, Pamphilon D (2007). Bone marrow harvest versus peripheral stem cell collection for haemopoietic stem cell donation in healthy donors (Protocol). Cochrane Databse of Systematic Reviews(1).
Murphy MF, Brunskill S, Doree C, Roberts DC, Hyde C (2007). Evidence base for transfusion medicine. ISBT Science Series(2), 204-208.
Board TN, Brunskill S, Doree C, Hyde C, Kay PR, Meek RD, Webster R, Galea G (2007). Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty. Cochrane Database of Systematic Reviews(1).
Board TN, Brunskill S, Dorree C, Hyde CJ, Kay PR, Meek RD, Webster R, Galea G (2007). Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty. (Protocol). Cochrane Database of Systmeatic Reviews(1).
Wood P, Stanworth S, Burton J, Jones A, Peckham DG, Green T, Hyde C, Chapel H, UK Primary Immunodeficiency Network (2007). Recognition, clinical diagnosis and management of patients with primary antibody deficiencies: a systematic review. Clin Exp Immunol, 149(3), 410-423. Abstract. Author URL.
Stanworth SJ, Birchall J, Doree CJ, Hyde C (2007). Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia. Cochrane Database Syst Rev(2). Abstract. Author URL.
Hearnshaw SA, Brunskill S, Doree C, Hyde C, Travis SPL, Murphy M (2007). Red cell transfusion for the management of upper gastrointestinal haemorrhage. Cochrane Database of Systematic Reviews(3).
Hearnshaw SA, Brunskill S, Doree C, Hyde CJ, Travis SPL, Murphy M (2007). Red cell transfusion for the management of upper gastrointestinal haemorrhage. (Protocol). Cochrane Database of Systematic Reviews(3).
Martin-Rendon E, Brunskill S, Doree C, Hyde C, Watt S, Mathur A (2007). Stem cell treatment for acute myocardial infarction.
Stanworth SJ, Brunskill SJ, Hyde CJ, Murphy MF, McClelland DBL (2006). Appraisal of the evidence for the clinical use of FFP and plasma fractions. Best Pract Res Clin Haematol, 19(1), 67-82. Abstract. Author URL.
Davenport C, Cheng EYL, Kwok YTT, Lai AHO, Wakabayashi T, Hyde C, Connock M (2006). Assessing the diagnostic test accuracy of natriuretic peptides and ECG in the diagnosis of left ventricular systolic dysfunction: a systematic review and meta-analysis. Br J Gen Pract, 56(522), 48-56. Abstract. Author URL.
Pawson R, Brunskill S, Murphy MF, Doree C, Hyde CJ, Daly J (2006). Different threshold levels for red blood cell transfusions in patients with haematological malignancy. cochrane Database of Systematic Reviews(3).
Bohlius J, Wilson J, Seidenfeld J, Piper M, Schwarzer G, Sandercock J, Trelle S, Weingart O, Bayliss S, Brunskill S, et al (2006). Erythropoietin or darbepoetin for patients with cancer. Cochrane Database Syst Rev(3). Abstract. Author URL.
Meads C, Hyde C (2006). How much is the cost of visual impairment: caveat emptor. Pharmacoeconomics, 24(2), 207-209. Author URL.
Hyde C, Stanworth SJ, Murphy M, Brunskill S, Stearn B, Howell C (2006). P16What is the Best Way to Achieve Sustained Changes in Transfusion Prescribing Behaviour by Physicians?. Transfusion Medicine, 16(s1), 31-32.
Bohlius J, Wilson J, Seidenfeld J, Piper M, Schwarzer G, Sandercock J, Trelle S, Weingart O, Bayliss S, Djulbegovic B, et al (2006). Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patients. J Natl Cancer Inst, 98(10), 708-714. Abstract. Author URL.
Willis BH, Barton P, Pearmain P, Bryan S, Hyde C (2005). Cervical screening programmes: can automation help? Evidence from systematic reviews, an economic analysis and a simulation modelling exercise applied to the UK. Health Technol Assess, 9(13), 1-iii. Abstract. Author URL.
Roberts DJ, Rees D, Howard J, Hyde C, Alderson P, Brunskill S (2005). Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia. Cochrane Database Syst Rev(4). Abstract. Author URL.
Bohlius J, Wilson J, Bayliss S, Djulbegovic B, Hyde C, Trelle S, Weingart O, Brunskill S, Sandercock J, Seidenfeld J, et al (2005). Epoetin and Darbepoetin to Treat Cancer Patients: Updated Meta-Analysis Results. Blood, 106(11).
Paulus U, Massey E, Doree C, Brunskill S, Hyde CJ, Lucas G, Marks D, Navarrete C, Stanworth S (2005). Granulocyte transfusions for preventing infections in patients with neuropenia or neurophil dysfunction. Cochrane Database of Systematic Reviews(3).
Stanworth SJ, Massey E, Hyde C, Brunskill S, Lucas G, Navarrete C, Marks DI (2005). Granulocyte transfusions for treating infections in patients with neutropenia or neutrophil dysfunction. Cochrane Database Syst Rev(3). Abstract. Author URL.
Stanworth SJ, Hyde C, Brunskill S, Murphy MF (2005). Platelet transfusion prophylaxis for patients with haematological malignancies: where to now?. Br J Haematol, 131(5), 588-595. Abstract. Author URL.
Dretzke J, Frew E, Davenport C, Barlow J, Stewart-Brown S, Sandercock J, Bayliss S, Raftery J, Hyde C, Taylor R, et al (2005). The effectiveness and cost-effectiveness of parent training/education programmes for the treatment of conduct disorder, including oppositional defiant disorder, in children. Health Technol Assess, 9(50), iii-233. Abstract. Author URL.
Simpson S, Hyde C, Cook A, Packer C, Stevens A (2004). Assessing the accuracy of forecasting: applying standard diagnostic assessment tools to a health technology early warning system. Int J Technol Assess Health Care, 20(3), 381-384. Abstract. Author URL.
Song FJ, Fry-Smith A, Davenport C, Bayliss S, Adi Y, Wilson JS, Hyde C (2004). Identification and assessment of ongoing trials in health technology assessment reviews. HEALTH TECHNOLOGY ASSESSMENT, 8(44), 1-+. Author URL.
Stanworth SJ, Brunskill SJ, Hyde CJ, McClelland DBL, Murphy MF (2004). Is fresh frozen plasma clinically effective? a systematic review of randomized controlled trials. Br J Haematol, 126(1), 139-152. Abstract. Author URL.
Roberts D, Rees D, Howard J, Williams S, Hyde CJ, Brunskill S (2004). Oral deferiprone for iron chelation in people with thalassaemia. Cochrane Database of Systematic Reviews(3).
Meads C, Hyde C (2004). Photodynamic therapy with verteporfin is effective, but how big is its effect? Results of a systematic review. Br J Ophthalmol, 88(2), 212-217. Abstract. Author URL.
Stanworth SJ, Hyde C, Heddle N, Rebulla P, Brunskill S, Murphy MF (2004). Prophylactic platelet transfusion for haemorrhage after chemotherapy and stem cell transplantation. Cochrane Database Syst Rev(4). Abstract. Author URL.
Taus C, Solari A, D'Amico R, Branas P, Hyde CJ, Giuliani G, Pucci E (2003). Amantadine for fatigue in multiple sclerosis. Cochrane Database of Sytematic Reviews(2).
Meads C, Salas C, Roberts T, Moore D, Fry-Smith A, Hyde C (2003). Clinical effectiveness and cost-utility of photodynamic therapy for wet age-related macular degeneration: a systematic review and economic evaluation. Health Technol Assess, 7(9), v-98. Author URL.
Clark TJ, Voit D, Gupta JK, Hyde C, Song F, Khan KS, Mol BW (2003). Hysteroscopy is an accurate diagnostic test for endometrial cancer in women with abnormal uterine bleeding - Meta-analysis. Evidence-based Obstetrics and Gynecology, 5(2), 94-95.
Meads C, Hyde C (2003). What is the cost of blindness?. Br J Ophthalmol, 87(10), 1201-1204. Author URL.
Clark TJ, Voit D, Gupta JK, Hyde C, Song F, Khan KS (2002). Accuracy of hysteroscopy in the diagnosis of endometrial cancer and hyperplasia: a systematic quantitative review. JAMA, 288(13), 1610-1621. Abstract. Author URL.
Adi Y, Ashcroft D, Browne K, Beech A, Fry-Smith A, Hyde C (2002). Clinical effectiveness and cost-consequences of selective serotonin reuptake inhibitors in the treatment of sex offenders. Health Technol Assess, 6(28), 1-66. Author URL.
Song F, Raftery J, Aveyard P, Hyde C, Barton P, Woolacott N (2002). Cost-effectiveness of pharmacological interventions for smoking cessation: a literature review and a decision analytic analysis. Med Decis Making, 22(5 Suppl), S26-S37. Abstract. Author URL.
Hyde C, Wake B, Bryan S, Barton P, Fry-Smith A, Davenport C, Song F (2002). Fludarabine as second-line therapy for B cell chronic lymphocytic leukaemia: a technology assessment. Health Technol Assess, 6(2), 1-89. Author URL.
Jordan R, Gold L, Cummins C, Hyde C, Rutherford GW (2002). Increasing the number of drugs in antiretroviral therapy may improve survival in people with HIV infection. Evidence-Based Healthcare, 6(4), 163-164.
Wake B, Hyde C, Bryan S, Barton P, Song F, Fry-Smith A, Davenport C (2002). Rituximab as third-line treatment for refractory or recurrent Stage III or IV follicular non-Hodgkin's lymphoma: a systematic review and economic evaluation. Health Technol Assess, 6(3), 1-85. Author URL.
Jordan R, Gold L, Cummins C, Hyde C (2002). Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy. BMJ, 324(7340). Abstract. Author URL.
Woolacott NF, Jones L, Forbes CA, Mather LC, Sowden AJ, Song FJ, Raftery JP, Aveyard PN, Hyde CJ, Barton PM, et al (2002). The clinical effectiveness and cost-effectiveness of bupropion and nicotine replacement therapy for smoking cessation: a systematic review and economic evaluation. Health Technol Assess, 6(16), 1-245. Author URL.
Reeves E, Lilford R, Howie F, Middleton J, Hyde C, Elbourne D, Oakley A, Gough D (2001). Collaboration with the Campbell Collaboration. BMJ, 323(7323).
Robert IE, Hyde CJ, Bridgman SA (2001). Orthopaedic fractures: trends in randomised controlled trials. Injury, 32(10), 779-782. Abstract. Author URL.
Sandercock J, Burls A, Hyde C, Fry-Smith A, Barton P, Bryan S, Stewart A (2001). Riluzole for motor neurone disease. More trials are needed. BMJ, 322(7297). Author URL.
Parkes J, Hyde C, Deeks J, Milne R (2001). Teaching critical appraisal skills in health care settings. Cochrane Database Syst Rev(3). Abstract. Author URL.
Stewart A, Sandercock J, Bryan S, Hyde C, Barton PM, Fry-Smith A, Burls A (2001). The clinical effectiveness and cost-effectiveness of riluzole for motor neurone disease: a rapid and systematic review. Health Technology Assessment, 5(2).
Meads C, Cummins C, Jolly K, Stevens A, Burls A, Hyde C (2000). Coronary artery stents in the treatment of ischaemic heart disease: a rapid and systematic review. Health Technology Assessment, 4(23).
Awonuga AO, Dwarakanath LS, Johanson R, Hyde C, Taylor R, Khan KS (2000). Critical appraisal workshops to promote evidence-based healthcare. J Obstet Gynaecol, 20(1), 10-14. Abstract. Author URL.
Packer C, Hyde CJ (2000). Does providing timely access to and advice on exisiting reviews of research influence Health Authority purchasing. Public Health Medicine, 2(1), 20-24.
Awonuga A, Dwarakanath LS, Johanson R, Hyde C, Taylor R, Khan KS (2000). Erratum: Critical appraisal workshops to promote evidence-based healthcare (Journal of Obstetrics and Gynaecology (2000) 20, 1 (10-14)). Journal of Obstetrics and Gynaecology, 20(2).
Delaney B, Wilson S, Fitzmaurice D, Hyde C, Hobbs R (2000). Near-patient tests in primary care: setting the standards for evaluation. J Health Serv Res Policy, 5(1), 37-41. Abstract. Author URL.
Hyde CJ, Robert IE, Sinclair AJ (2000). The effects of supporting discharge from hospital to home in older people. Age and Ageing, 29
Branas P, Jordan R, Fry-Smith A, Burls A, Hyde C (2000). Treatments for fatigue in multiple sclerosis: a rapid and systematic review. Health Technology Assessment, 4(27).
Hyde CJ, Fry-Smith A, Young J (1999). Finding literature on pre-hospital emergency care. Pre-hospiotal Immediate Care, 3(1), 22-32.
Young J, Fry-Smith A, Hyde C (1999). Lung volume reduction surgery (LVRS) for chronic obstructive pulmonary disease (COPD) with underlying severe emphysema. Thorax, 54(9), 779-789. Abstract. Author URL.
Hyde C (1999). Near patient testing in diabetes clinics: appraising the costs and outcomes. Health Technol Assess, 15(3).
Delaney BC, Hyde CJ, McManus RJ, Wilson S, Fitzmaurice DA, Jowett S, Tobias R, Thorpe GH, Hobbs FD (1999). Systematic review of near patient test evaluations in primary care. BMJ, 319(7213), 824-827. Abstract. Author URL.
Chariot P, Pautot V, Due S, Mcmanus RJ, Wilson S, Delaney BC, Fitzmaurice DA, Tobias RS, Jowett S, Hobbs FDR, et al (1999). Usefulness of contacting other experts when conducting literature searches. BMJ, 319(7204).
McManus RJ, Wilson S, Delaney BC, Fitzmaurice DA, Hyde CJ, Tobias RS, Jowett S, Hobbs FD (1998). Review of the usefulness of contacting other experts when conducting a literature search for systematic reviews. BMJ, 317(7172), 1562-1563. Author URL.
Hobbs FD, Delaney BC, Fitzmaurice DA, Wilson S, Hyde CJ, Thorpe GH, Earl-Slater AS, Jowett S, Tobias RS (1997). A review of near patient testing in primary care. Health Technol Assess, 1(5), i-229. Abstract. Author URL.
Hyde CJ (1996). Active research dissemination in the West Midlands. Journal of Clinical Effectiveness, 1(1).
Hyde CJ, Fry-Smith A (1996). Preterm premature rupture of membranes. Lancet, 347(8995). Author URL.
Hyde CJ (1996). Using the evidence. A need for quantity, not quality?. Int J Technol Assess Health Care, 12(2), 280-287. Abstract. Author URL.
Fahey T, Hyde C, Milne R, Thorogood M (1995). The type and quality of randomized controlled trials (RCTs) published in UK public health journals. J Public Health Med, 17(4), 469-474. Abstract. Author URL.
Hyde C (1995). Who uses the Cochrane Pregnancy and Childbirth Database?. BMJ, 310(6987), 1140-1141. Author URL.
Chapters
Brunskill SJ, Prowse C, Garrioch M, Gill R, Hebert PP, Thompson J, Hyde C, Stanworth S, Roberts DJ (2011). Blood substitutes for avoiding allogeneic blood transfusion. In (Ed) Cochrane Database of Systematic Reviews, Wiley.
Pawson R, Brunskill S, Murphy MF, Doree C, Hyde C, Daly J (2009). Different threshold levels for red blood cell transfusions in patients with haematological malignancy. In (Ed) Cochrane Database of Systematic Reviews, Wiley.
Stanworth SJ, Brunskill SJ, Doree C, Hyde CJ (2009). Getting the most out of the evidence for transfusion medicine. In (Ed) Practical Transfusion Medicine: Third Edition, 513-521.
Stanworth SJ, Francis JJ, Eccles MP, Hyde CJ, Murphy MF, Tinmouth AT (2009). How to influence clinicians' use of blood - improving the transfusion practice in hospitals. In (Ed) Practical Transfusion Medicine: Third Edition, 522-529.
Pawson R, Brunskill S, Murphy MF, Dor��e C, Hyde C, Daly J (2006). Different threshold levels for red blood cell transfusions in patients with haematological malignancy. In (Ed) Cochrane Database of Systematic Reviews, Wiley.
Stanworth SJ, Brunskill SJ, Hyde CJ (2005). Getting the most out of the evidence for transfusion medicine. In Murphy MF, Pamphilon DH (Eds.) Practical transfusion medicine, Oxford: Blackwell Publishing, 436-444.
Paulus U, Massey E, Doree C, Brunskill S, Hyde C, Lucas G, Marks D, Navarrete C, Stanworth S (2005). Granulocyte transfusions for preventing infections in patients with neutropenia or neutrophil dysfunction. In (Ed) Cochrane Database of Systematic Reviews, Wiley.
Massey E, Stanworth S, Brunskill S, Hyde C, Lucas G, Marks D, Murphy M, Navarrete C, Pamphilon D, Roberts D, et al (2005). Granulocyte transfusions for treating infections in patients with neutropenia or neutrophil dysfunction. In (Ed) The Cochrane Database of Systematic Reviews, Wiley.
Roberts D, Rees D, Howard J, Williams S, Hyde C, Brunskill S, Doree CJ (2004). Oral deferiprone for iron chelation in people with thalassaemia. In (Ed) Cochrane Database of Systematic Reviews, Wiley.
Brunskill SJ, Prowse C, Garrioch M, Gill R, Hebert PP, Thompson J, Hyde C, Stanworth S, Roberts DJ (2003). Blood substitutes for avoiding allogeneic blood transfusion. In (Ed) Cochrane Database of Systematic Reviews, Wiley.
Roberts D, Rees D, Howard J, Hyde C, Stanworth S, Brunskill S (2003). Desferrioxamine mesylate for managing transfusional iron overload in people with thalassaemia. In (Ed) The Cochrane Database of Systematic Reviews, Wiley.
Murphy M, Stanworth S, Heddle N, Rebulla P, Brunskill S, Hyde C (2003). Prophylactic platelet transfusion for haemorrhage after chemotherapy and stem cell transplantation. In (Ed) The Cochrane Database of Systematic Reviews, Wiley.
Conferences
Lawday S, Flamey N, Fowler G, Leaning M, Dyar N, Daniels I, Smart N, Hyde C (2020). Comparing the Effect of Restorative Resection with Non-Restorative Excision for Non-Metastatic Rectal Cancer on Health Related Quality of Life: a Systematic Review of Interventional and Observational Studies Since 2012. Author URL.
Thompson AJ, Page O, Runswick E, Hyde C, Payne K (2018). FIRST DO NO HARM? EXPLORING THE INTERPRETATION OF NICE DIAGNOSTIC ASSESSMENTS WITH COST SAVINGS AND QALY LOSS. Author URL.
Varley-Campbell J, Dodman S, Coelho H, Cooper C, Barnish M, Mujica-Mota R, Hyde C, Hoyle M (2018). Full texts vs. conference abstract data, how does the message change?. HTAi 2018.
Hunt HA, Hyde CJ (2017). An overview of systematic reviews summarising the accuracy of brief cognitive assessments for identifying dementia in primary care. Methods for Evaluating Medical Tests and Biomarkers. 19th - 20th Jul 2016. Abstract.
Zhelev Z, Patel K, Youngman E, Peters J, Lowe J, Cooper C, Shields B, Hattersley A, Hyde C (2016). Autoantibody status as a predictor of future insulin deficiency in patients with diabetes: a systematic review. Author URL.
Haasova M, Jones-Hughes T, Peters J, Snowsill T, Coelho H, Crathorne L, Mujica Mota R, Varley-Campbell J, Huxley N, Moore J, et al (2016). Immunosuppressive therapy for renal transplantation in adults: a systematic review and network meta-analyses. Health Technology
Assessment international (HTAi). 10th - 14th May 2016. Abstract.
Hunt HA, Hyde CJ (2016). Overview (de)generation: a. review of reviews on the. diagnostic accuracy of. brief cognitive assessments for identifying dementia in primary care. 24th Cochrane Colloquium. 23rd - 27th Oct 2016. Abstract.
Peters JL, Anderson R, Shields BM, King S, Hudson M, Shepherd M, McDonald TJ, Pearson E, Hattersley AT, Hyde C, et al (2016). Strategies to identify individuals with MODY: results of a health economic model. Author URL.
Pang CL, Pilkington N, Roobottom C, Hyde C, Peters J (2016). THE VALUES OF CALCIUM SCORE AND COMPUTED TOMOGRAPHIC CORONARY ANGIOGRAPHY TO PREDICT HARD CARDIOVASCULAR OUTCOMES INDEPENDENTLY AND THEIR RESPECTIVE EXTRA VALUES IN ADDITION TO MULTI-VARIABLE RISK SCORE. Author URL.
di Ruffano LF, Dinnes J, Phillips-Taylor S, Davenport C, Hyde C, Deeks J (2015). Can we implement findings from RCTs of diagnostic tests? a review of reporting of test-treat interventions. Author URL.
Walker S, Hamilton W, Hyde C (2015). Quantification of the risk of cervical cancer in symptomatic primary care patients. Author URL.
Hyde CJ, Hunt HA (2015). Test evaluation and decision making – what further information is needed? (workshop). 23rd Cochrane Colloquium. 3rd - 7th Oct 2015. Abstract.
Huxley N, Snowsill T, Hoyle M, Crathorne L, Haasova M, Briscoe S, Coelho H, Medina-Lara A, Mujica-Mota R, Napier M, et al (2014). A COST-EFFECTIVENESS ANALYSIS OF ERYTHROPOIESIS-STIMULATING AGENTS FOR TREATING CANCER-TREATMENT INDUCED ANAEMIA. Author URL.
Bond M, Cooper C, Coelho H, Haasova M, Milner Q, Shawyer V, Hyde C, Powell R, Crathorne L (2014). First do no harm: pain relief for the peripheral venous cannulation of adults, a systematic review. WHO 22nd International HPH Conference.
Van Giessen A, Wilcher B, Peters J, Hyde C, Moons KG, de Wit GA, Koffijberg H (2014). HEALTH ECONOMIC EVALUATION OF DIAGNOSTIC AND PROGNOSTIC PREDICTION MODELS. A SYSTEMATIC REVIEW. Author URL.
Shields BM, Peters JL, Cooper C, Lowe J, Knight B, Powell R, Hyde CJ, Hattersley AT (2014). Is there an evidence base for the clinical features used to differentiate type 1 from type 2 diabetes? a systematic review of the literature. Author URL.
Snowsill T, Huxley N, Hoyle M, Crathorne L, Haasova M, Briscoe S, Coelho H, Medina-Lara A, Mota MR, Napier M, et al (2014). MODEL-BASED COST-UTILITY ANALYSIS OF ERYTHROPOIESIS-STIMULATING AGENTS FOR THE TREATMENT OF CANCER-TREATMENT INDUCED ANAEMIA IN THE UK NHS. Author URL.
Walker S, Hamilton W, Hyde C (2014). Quantification of the risk of breast cancer in symptomatic primary care patients. Author URL.
Huxley N, Haasova M, Crathorne L, Hyde C (2014). WHAT IS THE CLINICAL EFFECTIVENESS AND COST-EFFECTIVENESS OF ERYTHROPOIETIN-STIMULATING AGENTS FOR THE TREATMENT OF PATIENTS WITH CANCER-TREATMENT INDUCED ANAEMIA? INSIGHTS FROM CUMULATIVE META-ANALYSES (CMA) AND LESSONS FOR COST-EFFECTIVENESS ANALYSES. Author URL.
Huxley N, Snowsill T, Hoyle M, Jones-Hughes T, Coelho H, Cooper C, Frayling I, Hyde C (2013). COST-EFFECTIVENESS OF SYSTEMATIC TESTING FOR LYNCH SYNDROME IN PATIENTS NEWLY DIAGNOSED WITH COLORECTAL CANCER IN THE UNITED KINGDOM. Author URL.
Grigore B, Peters J, Hyde C, Stein K (2013). REPRESENTING UNCERTAINTY OF EXPERT OPINION IN HEALTH TECHNOLOGY ASSESSMENT THROUGH THE USE OF SUBJECTIVE PROBABILITIES. Author URL.
Bond M, Pavey T, Welch K, Cooper C, Garside R, Dean S, Hyde C (2012). PSYCHOLOGICAL CONSEQUENCES OF FALSE-POSITIVE SCREENING MAMMOGRAMS IN THE UK: a SYSTEMATIC REVIEW. Author URL.
Davenport CF, Hyde CJ (2012). SURVEY OF USE AND APPLICATION OF TEST ACCURACY MEASURES FOR DECISION MAKING IN PRIMARY CARE. Author URL.
Shields BM, McDonald TJ, Ellard S, Hyde C, Campbell M, Hattersley AT (2011). Should I test this patient for maturity onset diabetes of the young? a clinical prediction model to determine the probability of MODY. Author URL.
Stockton C, Francis JJ, Johnston M, Eccles MP, Stanworth SJ, Cuthbertson BH, Hyde C, Tinmouth A, Grimshaw J (2008). From theoretical domains to theory: Enhancing the selection of theory to understand clinicians' transfusion behaviour. Author URL.
Murphy M, Brunskill S, Stanworth S, Doree C, Hyde C, Roberts D (2008). How to further develop the evidence base for transfusion medicine. Author URL.
Francis JJ, Stockton C, Johnston M, Eccles MP, Stanworth S, Cuthbertson BH, Hyde C, Tinmouth A, Grimshaw J (2008). Predicting behavioural simulation from standard rating versus 'direct estimation' measure of intention, for transfusion behaviour. Author URL.
Chaudhuri K, Jobanputra P, Hyde CJ (2001). Meta-analysis of anti TNF therapies in rheumatoid arthritis. Author URL.
Reports
Barnish M, Varley-Campbell J, Coelho H, Dodman S, Snowsill T, Mujica-Mota R, Packman D, Ocean N, Kay T, Liversedge N, et al (2018). Biomarker tests to help diagnose preterm labour in symptomatic women with intact membranes: a systematic review.
Varley-Campbell J, Mujica-Mota R, Coelho H, Ocean N, Barnish M, Packman D, Dodman S, Cooper C, Snowsill T, Kay T, et al (2018). Biomarker tests to help diagnose preterm labour in women with intact membranes. NICE.
Jones-Hughes T, Snowsill T, Haasova M, Coelho H, Crathorne L, Cooper C, Mujica-Mota R, Peters J, Varley-Campbell J, Huxley N, et al (2015). Immunosuppressive therapy for kidney transplantation in adults (review of technology appraisal guidance 85). MTA for NICE. Author URL.
Crathorne L, Huxley N, Haasova M, Snowsill T, Jones-Hughes T, Hoyle M, Briscoe S, Coelho H, Long L, Medina-Lara A, et al (2014). The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer treatment-induced anaemia (including review of technology appraisal no. 142). Author URL.
Crathorne L, Cooper C, Coelho H, Haasova M, Milner Q, Shawyer V, Hyde C, Bond M (2013). Pain relief for peripheral venous cannulation of adults in routine treatment settings: a systematic review. Royal Devon and Exeter Foundation Trust Hospital, Exeter, University of Exeter.
Bond M, Pavey T, Welch K, Cooper C, Garside R, Dean S, Hyde C (2011). Systematic review of the psychological consequences of false-positive screening mammograms. NIHR HTA, NICE.
Pitt M, Crathorne L, Moxham T, Bond M, Hyde C (2009). Everolimus for the second-line treatment of advanced and/or metastatic renal cell carcinoma. NIHR HTA, NICE.
Greenheld W, Wilson J, Bayliss S, Hyde C (2008). The clinical and cost-effectiveness of intensive versus standard lipid lowering with statins in the prevention of cardiovascular events amongst patients with acute coronalry syndromes: a systematic review. Department of Public Health and Epidemiology, University of Birmingham.
Albon E, Adi Y, Hyde C (2008). The effectiveness and cost-effectiveness of coloured filters for reading disability: a systematic review. Department of Public Health and Epidemiology, University of Birmingham.
Liu Z, Albon E, Hyde C (2006). The effectiveness and cost effectiveness of immunoglobulin replacement therapy for primary immunodeficiency and chronic lymphocytic leukaemia: a systmatic review and economic evaluation. West Midland Health Technology Assessment Collaboration, Department of Public Health and Epidemiology, University of Birmingham.
Meads C, Knight T, Hyde C, Wilson J (2004). The clinical effectiveness and cost effectiveness of anitbiotic regimens for pelvic inflammatory disease. West Midland Health Technology Assessment Collaboration, Department of Public Health and Epidemiology, University of Birmingham.
Jordan R, Gold L, Hyde C, Cummins C (2002). Antiretroviral therapy for HIV infection in patients naive to prior treatment: a systmatic review of effectiveness and cost-effectiveness. University of Birmingham, Birmingham.
Taylor-Weetman K, Wake B, Hyde C (2002). Comparison of panoramic and bitewing radiography for the detection of dental caries: a systematic review of diagnostic tests. West Midland Health Technology Assessment Collaboration, Department of Public Health and Epidemiology, University of Birmingham.
Hancock S, Wake B, Hyde C (2002). Fludarabine as first line therapy for chronic lymphocytic leukaemia. West Midland Health Technology Assessment Collaboration, Department of Public Health and Epidemiology, University of Birmingham.
Burls A, Cummins C, Fry-Smith A, Gold L, Hyde C, Jordan R, Parry D, Marshall T, Stevens A, Wilson R, et al (2000). West Midlands Development and Evaluation Service Handbook (Version 2.2). University of Birmingham, Birmingham.
External Engagement and Impact
Awards
Fellow of the Faculty of Public Health 2003
Committee/panel activities
Member of the National Screening Committee (2017 to present)
Member NICE Diagnostics Appraisals Committee (2010 to 2020)
NHS Blood & Transplant Systematic Reviews Steering Committee (2009 to 2015)
External examiner for public health component of medical undergraduate course at University of Bristol (2005 to 2010)
Examiner for Faculty of Public Health (1998 to 2004)
Editorial responsibilities
Cochrane Diagnostic Test Accuracy Reviews Editorial Board (2009 to present)
Cochrane Dementia and Cognitive Improvement Group Coordinating Editor (2010 to 2019)
NHS Health Technology Assessment monograph Editor (2000 to 2010)
Regular peer reviewer for NIHR and Cochrane Collaboration
Invited lectures
The changing landscape of the clinical evaluation of biomarkers: Policy and economic perspectives. EuroMedLab Milano 2013 Congress. 21st May 2013.
Reviews of diagnostic technologies; update from the Cochrane Collaboration. InterTASC workshop, University of Warwick. 9th May 2012
Testing times; supporting the evaluation of tests. Opening of Forum at the University of Exeter. 2nd May 2012.
Teaching
Chris is an experienced lecturer on most aspects of evidence based practice but teaching is not part of his main current responsibilities at UEMS.He does however contribute regularly to teaching sessions and workshops as part of work for the Cochrane Collaboration.
He has supervised over 10 PhDs.
He has supervised many Masters and Medical Undergraduate projects.
Chris is an accredited Public Health trainer.
He is qualified life coach.
Modules
2023/24
- HPDM136 - Evidence to Decision: Health Technology Assessment, Health Policy and Resource Allocation
- HPDM136Z - Evidence to Decision: Health Technology Assessment, Health Policy and Resource Allocation
