Loading content
Dr Asami Oguro-Ando

Dr Asami Oguro-Ando

Lecturer

01392 408328

RILD Building Wellcome Wolfson Centre for Me

Dr. Oguro-Ando has been interested in life science since she was a child, especially, how lives play rolls in plasticity to the environment. For her interest, she took the basic science course in my bachelor and studied fundamental physics and biology, before studying for an MSc and PhD in the Molecular chaperone and protein degradation at the University of Tokyo, Health Science and Physiology. As she was finishing my PhD thesis, Neuropsychiatric disorders were fascinating to her that there were many genes characterized and few animal models established, but still, it is unclear. She was exhilarated by the potential for growth in the field and spent four years at Prof. Daniel Geschwind lab (UCLA) in US for her first posdoc, next three years at Prof. Peter Burbach lab (UMC Utrecht) in the Netherlands for her second posdoc to develop her specificities of Autism spectrum disorder (ASD) research and joined in University of Exeter medical school in 2016. 

Current Awards

  • 2016 FENS satellite meeting travel award, Copenhagen, Denmark
  • 2010 Keystone Symposia Scholarship award, Utah, USA
  • 2009 Cold Spring Harbor Laboratories Course Scholarship award, NY, USA 

Qualifications

  • Ph.D Life Science (University of Tokyo, Tokyo, Japan)

Career

2016- Lecturer, University of Exeter Medical School

2014-2016 JSPS postdoctoral fellow in abroad, UMC Utrecht, The Netherlands

2013-2014 Canon foundation postdoctoral fellow, UMC Utrecht, The Netherlands

2012-2013 Postdoctoral researcher, UMC Utrecht, The Netherlands

2011-2012 Postdoctoral researcher, UCLA, USA

2010-2011 Uehara life science foundation Postdoctoral fellow, UCLA, USA

2008-2010 JSPS postdoctoral fellow, UCLA, USA

Links

Research

Research interests

Asami’s group research aim is to further our understanding of the molecules, cells and circuits that underlie neurodevelopmental disorders affecting mental health including Autism is critical for developing more effective therapies for these disorders.

Genomics data has recently revealed causal relationships between specific genetic variation and risk for neuropsychiatric disease. However, there still remains a missing link tying genetic variation to changes at the molecular, cellular, and systems biology and behavior levels. My goal is to provide this “missing link” by using both high-throughput rodents model methodologies and experimental validation of their predictions in order to clarify how genetic risk factors exert their mechanistic influence on human behavior. My new research group has focused not only on discovering psychiatric disease-related genetic variation, but also on using model systems to uncover the biological mechanisms that underlie these associations.

Research projects

  • Evaluating the behavior and neuronal morphology in Autism associated mouse model

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

Oguro-Ando A, Zuko A, Kleijer KTE, Burbach JPH (2017). A current view on contactin-4, -5, and -6: Implications in neurodevelopmental disorders. Mol Cell Neurosci, 81, 72-83. Abstract.  Author URL.
Zuko A, Oguro-Ando A, Post H, Taggenbrock RLRE, van Dijk RE, Altelaar AFM, Heck AJR, Petrenko AG, van der Zwaag B, Shimoda Y, et al (2016). Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis. FRONTIERS IN MOLECULAR NEUROSCIENCE, 9 Author URL.
Zuko A, Oguro-Ando A, Post H, Taggenbrock RLRE, van Dijk RE, Altelaar AFM, Heck AJR, Petrenko AG, van der Zwaag B, Shimoda Y, et al (2016). Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis. Front Mol Neurosci, 9 Abstract.  Author URL.
Zuko A, Oguro-Ando A, van Dijk R, Gregorio-Jordan S, van der Zwaag B, Burbach JPH (2016). Developmental role of the cell adhesion molecule Contactin-6 in the cerebral cortex and hippocampus. Cell Adh Migr, 10(4), 378-392. Abstract.  Author URL.
Bruining H, Matsui A, Oguro-Ando A, Kahn RS, Van't Spijker HM, Akkermans G, Stiedl O, van Engeland H, Koopmans B, van Lith HA, et al (2015). Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development. Biol Psychiatry, 78(7), 485-495. Abstract.  Author URL.
Oguro-Ando A, Rosensweig C, Herman E, Nishimura Y, Werling D, Bill BR, Berg JM, Gao F, Coppola G, Abrahams BS, et al (2015). Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR. Mol Psychiatry, 20(9), 1069-1078. Abstract.  Author URL.
Berg JM, Lee C, Chen L, Galvan L, Cepeda C, Chen JY, Pe├▒agarikano O, Stein JL, Li A, Oguro-Ando A, et al (2015). JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron, 88(6), 1173-1191. Abstract.  Author URL.
Shimizu M, Oguro-Ando A, Ohoto-Fujita E, Atomi Y (2014). Toll-interacting protein pathway: degradation of an ubiquitin-binding protein. Methods Enzymol, 534, 323-330. Abstract.  Author URL.
Zuko A, Kleijer KTE, Oguro-Ando A, Kas MJH, van Daalen E, van der Zwaag B, Burbach JPH (2013). Contactins in the neurobiology of autism. Eur J Pharmacol, 719(1-3), 63-74. Abstract.  Author URL.
Oguro A, Kubota H, Shimizu M, Ishiura S, Atomi Y (2011). Protective role of the ubiquitin binding protein Tollip against the toxicity of polyglutamine-expansion proteins. Neurosci Lett, 503(3), 234-239. Abstract.  Author URL.
Oguro A, Sakurai T, Fujita Y, Lee S, Kubota H, Nagata K, Atomi Y (2006). The molecular chaperone HSP47 rapidly senses gravitational changes in myoblasts. Genes Cells, 11(11), 1253-1265. Abstract.  Author URL.
Sakurai T, Fujita Y, Ohto E, Oguro A, Atomi Y (2005). The decrease of the cytoskeleton tubulin follows the decrease of the associating molecular chaperone alphaB-crystallin in unloaded soleus muscle atrophy without stretch. FASEB J, 19(9), 1199-1201. Abstract.  Author URL.
Oguro A, Sakurai T, Okuno M, Nagata K, Atomi Y (2004). The change of HSP47, collagen specific molecular chaperone, expression in rat skeletal muscle may regulate collagen production with gravitational conditions. Biol Sci Space, 18(3), 150-151. Abstract.  Author URL.
Oguro A, Sakurai T, Otawa M, Okuno M, Atomi Y (2003). The content of heat shock protein 47 (HSP47), a collagen-specific stress protein, changes with gravitational conditions in skeletal muscle. Biol Sci Space, 17(3), 206-207. Abstract.  Author URL.

Publications by year


2017

Oguro-Ando A, Zuko A, Kleijer KTE, Burbach JPH (2017). A current view on contactin-4, -5, and -6: Implications in neurodevelopmental disorders. Mol Cell Neurosci, 81, 72-83. Abstract.  Author URL.

2016

Zuko A, Oguro-Ando A, Post H, Taggenbrock RLRE, van Dijk RE, Altelaar AFM, Heck AJR, Petrenko AG, van der Zwaag B, Shimoda Y, et al (2016). Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis. FRONTIERS IN MOLECULAR NEUROSCIENCE, 9 Author URL.
Zuko A, Oguro-Ando A, Post H, Taggenbrock RLRE, van Dijk RE, Altelaar AFM, Heck AJR, Petrenko AG, van der Zwaag B, Shimoda Y, et al (2016). Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis. Front Mol Neurosci, 9 Abstract.  Author URL.
Zuko A, Oguro-Ando A, van Dijk R, Gregorio-Jordan S, van der Zwaag B, Burbach JPH (2016). Developmental role of the cell adhesion molecule Contactin-6 in the cerebral cortex and hippocampus. Cell Adh Migr, 10(4), 378-392. Abstract.  Author URL.

2015

Bruining H, Matsui A, Oguro-Ando A, Kahn RS, Van't Spijker HM, Akkermans G, Stiedl O, van Engeland H, Koopmans B, van Lith HA, et al (2015). Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development. Biol Psychiatry, 78(7), 485-495. Abstract.  Author URL.
Oguro-Ando A, Rosensweig C, Herman E, Nishimura Y, Werling D, Bill BR, Berg JM, Gao F, Coppola G, Abrahams BS, et al (2015). Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR. Mol Psychiatry, 20(9), 1069-1078. Abstract.  Author URL.
Berg JM, Lee C, Chen L, Galvan L, Cepeda C, Chen JY, Pe├▒agarikano O, Stein JL, Li A, Oguro-Ando A, et al (2015). JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron, 88(6), 1173-1191. Abstract.  Author URL.

2014

Shimizu M, Oguro-Ando A, Ohoto-Fujita E, Atomi Y (2014). Toll-interacting protein pathway: degradation of an ubiquitin-binding protein. Methods Enzymol, 534, 323-330. Abstract.  Author URL.

2013

Zuko A, Kleijer KTE, Oguro-Ando A, Kas MJH, van Daalen E, van der Zwaag B, Burbach JPH (2013). Contactins in the neurobiology of autism. Eur J Pharmacol, 719(1-3), 63-74. Abstract.  Author URL.

2011

Oguro A, Kubota H, Shimizu M, Ishiura S, Atomi Y (2011). Protective role of the ubiquitin binding protein Tollip against the toxicity of polyglutamine-expansion proteins. Neurosci Lett, 503(3), 234-239. Abstract.  Author URL.

2006

Oguro A, Sakurai T, Fujita Y, Lee S, Kubota H, Nagata K, Atomi Y (2006). The molecular chaperone HSP47 rapidly senses gravitational changes in myoblasts. Genes Cells, 11(11), 1253-1265. Abstract.  Author URL.

2005

Sakurai T, Fujita Y, Ohto E, Oguro A, Atomi Y (2005). The decrease of the cytoskeleton tubulin follows the decrease of the associating molecular chaperone alphaB-crystallin in unloaded soleus muscle atrophy without stretch. FASEB J, 19(9), 1199-1201. Abstract.  Author URL.

2004

Oguro A, Sakurai T, Okuno M, Nagata K, Atomi Y (2004). The change of HSP47, collagen specific molecular chaperone, expression in rat skeletal muscle may regulate collagen production with gravitational conditions. Biol Sci Space, 18(3), 150-151. Abstract.  Author URL.

2003

Oguro A, Sakurai T, Otawa M, Okuno M, Atomi Y (2003). The content of heat shock protein 47 (HSP47), a collagen-specific stress protein, changes with gravitational conditions in skeletal muscle. Biol Sci Space, 17(3), 206-207. Abstract.  Author URL.

Back | Edit Profile