Angela Shore&tab=external&refresh | The Medical School

Professor Angela Shore

Professor of Cardiovascular Sciences and Scientific Director, NIHR Exeter Clinical Research Facility

A.C.Shore@exeter.ac.uk

01392 403091

Diabetes and Vascular Research Centre

Overview

Professor Angela Shore was the inaugural Vice-Dean Research for the University of Exeter Medical School, prior to which she was Interim Vice-Dean Research for the Peninsula College of Medicine and Dentistry. She is the Scientific Director of the NIHR Exeter Clinical Research Facility for Experimental Medicine and Associate Director for Experimental Medicine for the UKCRN diabetes research network.

Professor Shore graduated in Physiology from the University of Newcastle and was awarded her PhD for an investigation of the vascular mechanisms underlying fluid homeostasis in patients with Liver Disease. Following postdoctoral positions at the University of London, where she expanded her research into the vascular aspects of hypertension, Professor Shore moved to the Postgraduate Medical School Exeter to establish the clinical microvascular research unit funded by the Wellcome Trust.

Currently Professor Shore’s work, which is funded by the British Heart Foundation, Diabetes UK, European Union IMI JU and NIHR, investigates novel approaches to the identification of early vascular complications and patient stratification for cardiovascular risk. She was appointed Professor of Cardiovascular Science in 2000. As the Interim Vice Dean for Research and previously the Director for the Institute of Biomedical and Clinical Science, Professor Shore played a central role in the research success of the Peninsula College of Medicine and Dentistry, driving the research strategy, the appointment of new staff and the development of state of the art facilities. She also led the last three successful RAE submissions.

Professor Shore is committed to interdisciplinary research and was instrumental in the establishment of the University of Exeter Science Strategy Theme “Translational Medicine, Personalised Medicine and Public Health” to drive forward this approach.

Professor Shore is actively involved in Microcirculation research worldwide. She was Treasurer of the European Society for Microcirculation, and represents Europe on the International Liaison Committee.

Qualifications

PhD
BSc

Secretary contact details: Jill Weller, +44 (0) 1392 403064 Mondays and Tuesdays only

Research group links

Research

Research projects

Surrogate markers for Micro- and Macro-vascular hard endpoints for Innovative diabetes Tools (SUMMIT-IMI). An IMI funded project with 29 partners. The vascular work package in collaboration with Lund, Pisa, Dundee and Florence explores novel techniques to assess plaque structure, microvascular function and assess the use of optical coherence tomography to detect early changes in retinal thickness in patients with diabetes with and without cardiovascular disease.

Laser speckle imaging (LSI) – monitoring microsurgical free flaps during breast reconstruction surgery. Funded by TSB this project with Moor Instruments and Plastic surgeons at RD&E is testing the feasibility of the use of laser speckle in theatres to monitor perfusion in microsurgical free flaps.

Does dietary supplementation with nitrate enhance walking distance or exercise performance? Funded by Diabetes UK in collaboration with College of Life and Environmental Sciences, UoE, this study is using beetroot juice supplementation in patients with type 2 diabetes and COPD to assess whether the benefits seen in healthy individuals of reducing blood pressure and improving exercise efficiency translate to patients.

Is microvascular function altered by glucagon-like peptide-1 in humans, in vivo? A Diabetes UK funded studentship which explores whether natural and analogues of GLP-1 are vasoactive using the local application of the agents by microinjection and assessment of perfusion with laser Doppler Perfusion imaging.

Structure/function relationships in small vessels in health and disease determined by nonlinear microscopy and image-based modelling. A BHF funded project in collaboration with College of Physics, Engineering and Maths to undertake a detailed analysis of the 3D structure and organisation of the wall components in small human blood vessels, exploring their size and interactions and their contribution to the wall biomechanical properties.

Urinary microalbuminuria and microvascular function. This IBCS PhD studentship seeks to determine an accurate and precise method to measure urinary albumin below the current clinically used assay detection limit, to assess it physiological variability and to assess whether subtle changes in microvascular function are associated with small changes in albuminuria even within the low normal range.

Does improving venous return increase microvascular perfusion? A studentship funded by donation and in kind contributions from industry to explore the control of the venous circulation in vivo and in vitro.

Non-invasive estimation of coronary artery stenosis by computed tomography and computational flow analysis in collaboration with College of Physics, Engineering and Mathematics, UoE, Plymouth University Peninsula Medical School and PenCLAHrc. The study seeks to identify whether modelling can accurately predict pressure drops across stenosis in coronary arteries.

Glycocalyx in health and disease. A studentship assessing the glycocalyx with the glycocheck device in health and disease and exploring contributions an impaired glycocalyx makes to the ability of the microcirculation to respond normally to stimuli.

The regulation of the microvascular in health and disease and links to end organ damage. A series of studies assessing the normal relationships between tissue oxygenation and perfusion and how these relationships are altered by microvascular dysfunction; determining new ways to assess oxygen extraction; examining links between abnormal responses of the microcirculation to stress eg reperfusion and end organ damage in the heart and kidneys

Periodontal disease and microvascular function. A Colgate funded studentship investigating links between inflammation of the gum and microvascular dysfunction.

Systemic microvascular dysfunction in patients with angina and normal coronary arteries. A Gawthorn Trust funded project using Cardiac MRI and assessments of microvascular function peripherally.

Grants/Funding

Technology Strategy Board. Laser speckle feasibility study in theatre
NIHR Funding for Clinical Research Facilities for Experimental Medicine
UoE Open Innovation fund; Non-invasive estimation of coronary artery stenosis by computed tomography and computational flow analysis
Diabetes UK: Does dietary nitrate supplementation improve exercise capability in patients with type 2 diabetes
British Heart Foundation: Novel use of nonlinear microscopy and image-based modelling to determine the relationship between structure and function in small arteries and veins in health and diabetes
Philanthropic Donor: The role of veins in the control of the microcirculation
Wellcome-Wolfson Capital Award in Biomedical Science for the Wellcome Wolfson Medical Research Centre
National Institute of Academic Anaesthesia: Microvascular Imaging During Abdominal Surgery
Diabetes UK Studentship: Is microvascular function latered by glucagon-like
peptide-1 in humans, in vivo?
IMI SUMMIT: Surrogate markers for vascular micro- and macrovascular hard endpoints for innovative diabetes tools.
Colgate UK and Colgate Europe: Microcirculation in peridontal disease.
NIHR Capital Funding to support the Peninsula Clinical Research Facility
NIHR Infrastructure funding Peninsula NIHR Clinical Research Facility “An integrated physiological approach from the patient to gene and back again”

Publications

Journal articles

Bowtell J, Shore A, Jackman S (In Press). An appraisal of trials investigating the effects on macular pigment optical density of lutein and zeaxanthin dietary interventions: a narrative review. Nutrition Reviews

Shore A, De Marinis Y (In Press). Elevated circulating follistatin associates with an increased risk of type 2 diabetes. Nature Communications

Shore A (In Press). Microstructural Characterisation of Resistance Artery Remodelling in Diabetes Mellitus. Journal of Vascular Research

Thorn CE (In Press). Microstructure and mechanics of human resistance arteries. American Journal of Physiology - Heart and Circulatory Physiology

Casanova F, Gooding K, Shore A, Adingupu D, Mawson D, Ball C, Anning C, Aizawa K, Gates P, Strain W, et al (In Press). Weight change and sulphonylurea therapy are related to three-year change in microvascular function in people with type 2 diabetes. Diabetologia

Fitzpatrick NK, Chachay V, Capra S, Briskey D, Jackman S, Shore A, Bowtell J (2024). Assessing electronic device use behaviours in healthy adults: development and evaluation of a novel tool. BMC Public Health, 24(1). Abstract. Author URL.

Fitzpatrick NK, Chachay V, Shore A, Jackman S, Capra S, Bowtell J, Briskey D (2024). Building food composition tables: extraction methods to measure lutein and zeaxanthin concentrations in select Australian foods. International Journal of Food Science and Technology, 59(3), 1864-1875. Abstract.

Genovese F, Gonçalves I, Holm Nielsen S, Karsdal MA, Edsfeldt A, Nilsson J, Shore AC, Natali A, Khan F, Shami A, et al (2024). Plasma levels of PRO-C3, a type III collagen synthesis marker, are associated with arterial stiffness and increased risk of cardiovascular death. Atherosclerosis, 388, 117420-117420.

Aizawa K, Gates PE, Mawson DM, Casanova F, Gooding KM, Hope SV, Goncalves I, Nilsson J, Khan F, Colhoun HM, et al (2024). Type 2 diabetes exacerbates changes in blood pressure-independent arterial stiffness: cross-sectional and longitudinal evidence from the SUMMIT study. J Appl Physiol (1985), 136(1), 13-22. Abstract. Author URL.

Edsfeldt A, Gonçalves I, Vigren I, Jovanović A, Engström G, Shore AC, Natali A, Khan F, Nilsson J (2023). Circulating soluble IL-6 receptor associates with plaque inflammation but not with atherosclerosis severity and cardiovascular risk. Vascul Pharmacol, 152 Abstract. Author URL.

Aizawa K, Thompson C, Hughes AD, Parker KH, Shore AC, Vanhatalo A, Jones AM (2023). EFFECTS OF 2-WEEK DIETARY NITRATE SUPPLEMENTATION AND ANTIBACTERIAL MOUTHWASH TREATMENT ON RESERVOIR-EXCESS PRESSURE PARAMETERS IN HEALTHY OLDER ADULTS. Journal of Hypertension, 41(Suppl 3).

Fitzpatrick NK, Capra S, Shore A, Briskey D, Jackman S, Bowtell J, Chachay V (2023). Newly developed dietary assessment tools for lutein and zeaxanthin are correlated with 24-hour diet recalls, but are not a valid measure of intake in Australian and United Kingdom adults. Nutrition Research, 122, 68-79.

Williams J, Gilchrist M, Strain WD, Fraser D, Shore A (2022). 24-h Glycaemic profiles in peritoneal dialysis patients and non-dialysis controls with advanced kidney disease. Perit Dial Int, 42(5), 497-504. Abstract. Author URL.

Henkens MTHM, Raafs AG, Verdonschot JAJ, Linschoten M, van Smeden M, Wang P, van der Hooft BHM, Tieleman R, Janssen MLF, ter Bekke RMA, et al (2022). Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. BMC Geriatrics, 22(1). Abstract.

Williams J, Gilchrist M, Strain WD, Fraser D, Shore A (2022). An exploratory study of the relationship between systemic microcirculatory function and small solute transport in incident peritoneal dialysis patients. Perit Dial Int, 42(5), 513-521. Abstract. Author URL.

Linschoten M, Uijl A, Schut A, Jakob CEM, Romao LR, Bell RM, McFarlane E, Stecher M, Zondag AGM, van Iperen EPA, et al (2022). Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries. EUROPEAN HEART JOURNAL, 43(11), 1104-+. Author URL.

Casanova F, Tyrrell J, Beaumont RN, Ji Y, Jones SE, Hattersley AT, Weedon MN, Murray A, Shore AC, Frayling TM, et al (2022). Corrigendum to: a genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio. Human Molecular Genetics, 31(9).

Jordan AN, Anning C, Wilkes L, Ball C, Pamphilon N, Clark CE, Bellenger NG, Shore AC, Sharp ASP, Valderas JM, et al (2022). Cross-cultural adaptation of the Spanish MINICHAL instrument into English for use in the United Kingdom. Health and Quality of Life Outcomes, 20(1).

Clark CE, Warren FC, Boddy K, McDonagh STJ, Moore SF, Teresa Alzamora M, Ramos Blanes R, Chuang S-Y, Criqui MH, Dahl M, et al (2022). Higher Arm Versus Lower Arm Systolic Blood Pressure and Cardiovascular Outcomes: a Meta-Analysis of Individual Participant Data from the INTERPRESS-IPD Collaboration. Hypertension, 79(10), 2328-2335. Abstract. Author URL.

Carmichael J, Fadavi H, Ishibashi F, Howard S, Boulton AJM, Shore AC, Tavakoli M (2022). Implementation of corneal confocal microscopy for screening and early detection of diabetic neuropathy in primary care alongside retinopathy screening: Results from a feasibility study. Frontiers in Endocrinology, 13 Abstract.

Khan F, Gonçalves I, Shore AC, Natali A, Palombo C, Colhoun HM, Östling G, Casanova F, Kennbäck C, Aizawa K, et al (2022). Plaque characteristics and biomarkers predicting regression and progression of carotid atherosclerosis. Cell Rep Med, 3(7). Abstract. Author URL.

Aizawa K, Hughes AD, Casanova F, Gates PE, Mawson DM, Gooding KM, Gilchrist M, Goncalves I, Nilsson J, Khan F, et al (2022). Reservoir Pressure Integral is Independently Associated with the Reduction in Renal Function in Older Adults. Hypertension, 79(10), 2364-2372. Abstract. Author URL.

To C, Aizawa K, Gates PE, Parker KH, Hughes AD, Shore AC (2022). SHORT-TERM HIGH SALT INTAKE ADVERSELY AFFECTS PARAMETERS DERIVED FROM RESERVOIR-EXCESS PRESSURE ANALYSIS AND CENTRAL ARTERY HAEMODYNAMICS IN OVERWEIGHT/OBESE ADULTS. Journal of hypertension, 40 Abstract.

Leonetti S, Tricò D, Nesti L, Baldi S, Kozakova M, Goncalves I, Nilsson J, Shore A, Khan F, Natali A, et al (2022). Soluble CD40 receptor is a biomarker of the burden of carotid artery atherosclerosis in subjects at high cardiovascular risk. Atherosclerosis, 343, 1-9. Abstract. Author URL.

He J, Bellenger NG, Ludman AJ, Shore AC, Strain WD (2022). Treatment of myocardial ischaemia-reperfusion injury in patients with ST-segment elevation myocardial infarction: promise, disappointment, and hope. Rev Cardiovasc Med, 23(1). Abstract. Author URL.

Carmichael J, Fadavi H, Ishibashi F, Shore AC, Tavakoli M (2021). Advances in Screening, Early Diagnosis and Accurate Staging of Diabetic Neuropathy. FRONTIERS IN ENDOCRINOLOGY, 12 Author URL.

McDonagh STJ, Sheppard JP, Warren FC, Boddy K, Farmer L, Shore H, Williams P, Lewis PS, Baumber R, Fordham J, et al (2021). Arm Based on LEg blood pressures (ABLE-BP): can systolic leg blood pressure measurements predict systolic brachial blood pressure? Protocol for an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration. BMJ Open, 11(3), e040481-e040481. Abstract.

Aizawa K, Gates PE, Mawson DM, Elyas S, Casanova F, Gooding KM, Adingupu DD, Strain WD, Shore AC (2021). Carotid–femoral pulse wave velocity acquisition methods and their associations with cardiovascular risk factors and subclinical biomarkers of vascular health. Journal of Hypertension, 40(4), 658-665. Abstract.

Elyas S, Adingupu D, Aizawa K, Casanova F, Gooding K, Fulford J, Mawson D, Gates PE, Shore AC, Strain D, et al (2021). Cerebral small vessel disease, systemic vascular characteristics and potential therapeutic targets. Aging, 13(18), 22030-22039.

Linschoten M, Uijl A, Schut A, Jakob CEM, Romão LR, Bell RM, McFarlane E, Stecher M, Zondag AGM, van Iperen EPA, et al (2021). Clinical presentation, disease course and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease – a cohort study across eighteen countries. Abstract.

Jordan A, Anning C, Wilkes L, Ball C, Pamphilon N, Clark CE, Bellenger NG, Shore AC, Sharp ASP, Valderas JM, et al (2021). Cross-Cultural Adaptation of the Spanish MINICHAL Instrument into English for Use in the United Kingdom. Abstract.

Östlund Papadogeorgos N, Kuhl J, Shore A, Kahan T, Jörneskog G, Kalani M (2021). Effects of exenatide on microvascular reactivity in patients with type 2 diabetes and coronary artery disease: a randomized controlled study. Microcirculation, 28(2). Abstract. Author URL.

Strain WD, Elyas S, Wedge N, Mounce L, Henley W, James M, Shore AC (2021). Evaluation of microalbuminuria as a prognostic indicator after a TIA or minor stroke in an outpatient setting: the prognostic role of microalbuminuria in TIA evolution (ProMOTE) study. BMJ Open, 11(9), e043253-e043253. Abstract.

Thorn CE, Adio AO, Fox RH, Gardner AM, Winlove CP, Shore AC (2021). Intermittent compression induces transitory hypoxic stimuli, upstream vasodilation and enhanced perfusion of skin capillaries, independent of age and diabetes. J Appl Physiol (1985), 130(4), 1072-1084. Abstract. Author URL.

Jordan AN, Fulford J, Gooding K, Anning C, Wilkes L, Ball C, Pamphilon N, Mawson D, Clark CE, Shore AC, et al (2021). Morphological and functional cardiac consequences of rapid hypertension treatment: a cohort study. Journal of Cardiovascular Magnetic Resonance, 23(1), 122-122.

Hubbard T, Dudgeon A, Ferguson D, Shore A, Stone N (2021). P100. High wavenumber Raman spectroscopy tissue differentiation for intraoperative margin analysis. European Journal of Surgical Oncology, 47(5).

Aizawa K, Casanova F, Gates PE, Mawson DM, Gooding KM, Strain WD, Östling G, Nilsson J, Khan F, Colhoun HM, et al (2021). Reservoir-Excess Pressure Parameters Independently Predict Cardiovascular Events in Individuals with Type 2 Diabetes. Hypertension, 78(1), 40-50. Abstract.

Shami A, Edsfeldt A, Bengtsson E, Nilsson J, Shore AC, Natali A, Khan F, Lutgens E, Goncalves I (2021). Soluble CD40 Levels in Plasma Are Associated with Cardiovascular Disease and in Carotid Plaques with a Vulnerable Phenotype. JOURNAL OF STROKE, 23(3), 367-+. Author URL.

Holm Nielsen S, Edsfeldt A, Tengryd C, Gustafsson H, Shore AC, Natali A, Khan F, Genovese F, Bengtsson E, Karsdal M, et al (2021). The novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis. Journal of Internal Medicine, 290(1), 179-189. Abstract.

Hubbard TJE, Dudgeon AP, Ferguson DJ, Shore AC, Stone N (2021). Utilization of Raman spectroscopy to identify breast cancer from the water content in surgical samples containing blue dye. Translational Biophotonics, 3(2). Abstract.

Casanova F, Wood AR, Yaghootkar H, Beaumont RN, Jones SE, Gooding KM, Aizawa K, Strain WD, Hattersley AT, Khan F, et al (2020). A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function. Diabetes, 69(5), 1072-1082. Abstract. Author URL.

Clark C, Warren F, Boddy K, McDonagh S, Moore S, Goddard J, Reed N, Turner M, Alzamora MT, Ramos Blanes R, et al (2020). Associations Between Systolic Interarm Differences in Blood Pressure and Cardiovascular Disease Outcomes and Mortality: Individual Participant Data Meta-Analysis, Development and Validation of a Prognostic Algorithm: the INTERPRESS-IPD Collaboration. Hypertension, n/a, 1-12.

Van Zuydam NR, Ladenvall C, Voight BF, Strawbridge RJ, Fernandez-Tajes J, Rayner NW, Robertson NR, Mahajan A, Vlachopoulou E, Goel A, et al (2020). Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus. Circulation: Genomic and Precision Medicine, 13(6). Abstract.

Williams J, Gilchrist M, Fraser D, Strain D, Shore A (2020). P1161CUTANEOUS MICROCIRCULATORY DYSFUNCTION IN PERITONEAL DIALYSIS PATIENTS. Nephrology Dialysis Transplantation, 35(Supplement_3).

Hubbard T, Ferguson D, Shore A, Stone N (2020). P122: Raman spectroscopy for intraoperative margin analysis in breast conserving surgery. European Journal of Surgical Oncology, 46(6).

Riddell A, Kirkwood J, Smallwood M, Winyard P, Knight B, Steer K, Puddicombe L, Romanczuk L, Shore A, Gilchrist M, et al (2020). P1612CAN THE URINARY NITRATE TO CREATININE RATIO BE USED AS a MARKER FOR KIDNEY TRANSPLANT REJECTION?. Nephrology Dialysis Transplantation, 35(Supplement_3).

Aizawa K, Casanova F, Mawson D, Gooding K, Elyas S, Adingupu D, Strain D, Gates P, Shore A (2020). P17 Comparisons of Carotid-femoral Pulse Wave Velocity Obtained from the Surface-distance Measurement and from the Population-derived Distance Formula: Associations with Macro- and Microvascular Alterations in Older Adults. Artery Research, 25(Suppl 1), s60-s60.

Kozakova M, Morizzo C, Penno G, Shore AC, Nilsson J, Palombo C (2020). Plasma Homocysteine and Cardiovascular Organ Damage in a Population with a High Prevalence of Risk Factors. J Clin Endocrinol Metab, 105(8). Abstract. Author URL.

Gooding KM, Lienczewski C, Papale M, Koivuviita N, Maziarz M, Andersson A-MD, Sharma K, Pontrelli P, Hernandez AG, Bailey J, et al (2020). Prognostic Imaging Biomarkers for Diabetic Kidney Disease (iBEAt): Study protocol. Abstract.

Gooding KM, Lienczewski C, Papale M, Koivuviita N, Maziarz M, Dutius Andersson A-M, Sharma K, Pontrelli P, Garcia Hernandez A, Bailey J, et al (2020). Prognostic imaging biomarkers for diabetic kidney disease (iBEAt): study protocol. BMC Nephrology, 21(1). Abstract.

Jordan AN, Anning C, Wilkes L, Ball C, Pamphilon N, Clark CE, Bellenger NG, Shore AC, Sharp ASP (2020). Rapid treatment of moderate to severe hypertension using a novel protocol in a single-centre, before and after interventional study. J Hum Hypertens, 34(2), 165-175. Abstract. Author URL.

Williams JK, Smallwood MJ, Benjamin N, D'Souza RJ, Shore AC, Winyard PG, Gilchrist M (2020). Renal nitrate clearance in chronic kidney disease. Nitric Oxide, 97, 16-19.

Williams J, Gilchrist M, Strain D, Fraser D, Shore A (2020). The systemic microcirculation in dialysis populations. Microcirculation, 27(5). Abstract. Author URL.

Riddell A, Kirkwood J, Smallwood M, Winyard P, Knight B, Romanczuk L, Shore A, Gilchrist M (2020). Urinary nitrate concentration as a marker for kidney transplant rejection. BMC Nephrol, 21(1). Abstract. Author URL.

To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH (2019). "Reply: Intra-operative tissue perfusion measurement by Laser Speckle Imaging (LSI): a potential aid for reducing post-operative complications in free flap breast reconstructions.". Plast Reconstr Surg Author URL.

Casanova F, Tyrrell J, Beaumont RN, Ji Y, Jones SE, Hattersley AT, Weedon MN, Murray A, Shore AC, Frayling TM, et al (2019). A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio. Hum Mol Genet, 28(24), 4197-4207. Abstract. Author URL.

Aizawa K, Ramalli A, Sbragi S, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2019). Arterial wall shear rate response to reactive hyperaemia is markedly different between young and older humans. J Physiol, 597(16), 4151-4163. Abstract. Author URL.

Ramalli A, Aizawa K, Shore AC, Morizzo C, Palombo C, Lenge M, Tortoli P (2019). Continuous Simultaneous Recording of Brachial Artery Distension and Wall Shear Rate: a New Boost for Flow-Mediated Vasodilation. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 66(3), 463-471. Abstract.

To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH (2019). Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: a Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction. Plast Reconstr Surg, 143(2), 287e-292e. Abstract. Author URL.

To C, Rees-Lee JE, Gush RJ, Cawrse NH, Shore AC, Wilson ADH (2019). Letter to the Editor: the use of indocyanine green angiography in postmastectomy reconstruction: Do outcomes improve over time?. J Plast Reconstr Aesthet Surg, 72(9), 1576-1606. Author URL.

Aung MM, Slade K, Freeman LAR, Kos K, Whatmore JL, Shore AC, Gooding KM (2019). Locally delivered GLP-1 analogues liraglutide and exenatide enhance microvascular perfusion in individuals with and without type 2 diabetes. Diabetologia, 62(9), 1701-1711. Abstract. Author URL.

Natali A, Nesti L, Venturi E, Shore AC, Khan F, Gooding K, Gates PE, Looker HC, Dove F, Goncalves I, et al (2019). Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: a nested, case-control study. Diabetes Obes Metab, 21(2), 412-416. Abstract. Author URL.

Hubbard TJE, Shore A, Stone N (2019). Raman spectroscopy for rapid intra-operative margin analysis of surgically excised tumour specimens. Analyst, 144(22), 6479-6496. Abstract. Author URL.

To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH (2019). Reply: Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: a Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction. Plast Reconstr Surg, 144(5), 935e-936e. Author URL.

Chapman DP, Gooding KM, McDonald TJ, Shore AC (2019). Stability of urinary albumin and creatinine after 12 months storage at -20 °C and -80 °C. Pract Lab Med, 15 Abstract. Author URL.

Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Östling G, Khan F, Colhoun HM, Palombo C, et al (2018). 3.2 Reservoir Pressure Integral is Independently Associated with the Reduction in Renal Function in an Older Population. Artery Research, 24(1), 72-73.

van Zuydam NR, Ahlqvist E, Sandholm N, Deshmukh H, Rayner NW, Abdalla M, Ladenvall C, Ziemek D, Fauman E, Robertson NR, et al (2018). A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects with Type 2 Diabetes. Diabetes, 67(7), 1414-1427. Abstract. Author URL.

Old O, Lloyd G, Isabelle M, Almond LM, Kendall C, Baxter K, Shepherd N, Shore A, Stone N, Barr H, et al (2018). Automated cytological detection of Barrett's neoplasia with infrared spectroscopy. J Gastroenterol, 53(2), 227-235. Abstract. Author URL.

Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C, et al (2018). Brachial artery vasodilatory response and wall shear rate determined by multigate Doppler in a healthy young cohort. J Appl Physiol (1985), 124(1), 150-159. Abstract. Author URL.

Weir-McCall JR, Brown L, Summersgill J, Talarczyk P, Bonnici-Mallia M, Chin SC, Khan F, Struthers AD, Sullivan F, Colhoun HM, et al (2018). Development and Validation of a Path Length Calculation for Carotid-Femoral Pulse Wave Velocity Measurement: a TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture. Hypertension, 71(5), 937-945. Abstract. Author URL.

Clark C, Boddy K, Warren F, McDonagh S, Taylor R, Aboyans V, Cloutier L, McManus R, Shore A, Campbell J, et al (2018). INTER-ARM DIFFERENCES IN BLOOD PRESSURE AND MORTALITY: INDIVIDUAL PATIENT DATA META-ANALYSIS AND DEVELOPMENT OF a PROGNOSTIC ALGORITHM (INTERPRESS-IPD COLLABORATION). Canadian Journal of Cardiology, 34(10).

Gates PE, Gurung A, Mazzaro L, Aizawa K, Elyas S, Strain WD, Shore AC, Shandas R (2018). Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry. Ultrasound Med Biol, 44(7), 1392-1401. Abstract. Author URL.

Shore AC, Colhoun HM, Natali A, Palombo C, Khan F, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, et al (2018). Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: the SUMMIT VIP Study. Diabetes Care, 41(10), 2212-2219. Abstract. Author URL.

Thorn CE, Knight B, Pastel E, McCulloch LJ, Patel B, Shore AC, Kos K (2017). Adipose tissue is influenced by hypoxia of obstructive sleep apnea syndrome independent of obesity. Diabetes Metab, 43(3), 240-247. Abstract. Author URL.

Clark CE, Boddy K, Warren FC, Taylor RS, Aboyans V, Cloutier L, McManus RJ, Shore AC, Campbell JL (2017). Associations between interarm differences in blood pressure and cardiovascular disease outcomes: protocol for an individual patient data meta-analysis and development of a prognostic algorithm. BMJ Open, 7(6). Abstract. Author URL.

Petrie JR, Chaturvedi N, Ford I, Brouwers MCGJ, Greenlaw N, Tillin T, Hramiak I, Hughes AD, Jenkins AJ, Klein BEK, et al (2017). Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial. The Lancet Diabetes & Endocrinology, 5(8), 597-609.

Gurung A, Gates PE, Mazzaro L, Fulford J, Zhang F, Barker AJ, Hertzberg J, Aizawa K, Strain WD, Elyas S, et al (2017). Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging. Ultrasound Med Biol, 43(8), 1618-1627. Abstract. Author URL.

Pastel E, McCulloch LJ, Ward R, Joshi S, Gooding KM, Shore AC, Kos K (2017). GLP-1 analogue-induced weight loss does not improve obesity-induced AT dysfunction. Clin Sci (Lond), 131(5), 343-353. Abstract. Author URL.

Gilchrist M, Shore A (2017). Inorganic Nitrate: Marker or Mediator of Mortality?. J Am Heart Assoc, 6(11). Author URL.

Jordan AN, Shore AC (2017). Insights into the microvascular rarefaction of hypertension. Journal of Xiangya Medicine, 2(2).

Petrie JR, Chaturvedi N, Ford I, Hramiak I, Hughes AD, Jenkins AJ, E. Klein B, Klein R, Ooi TC, Rossing P, et al (2017). Metformin in adults with type 1 diabetes: <scp>D</scp>esign and methods of <scp>REducing</scp> with <scp>MetfOrmin V</scp>ascular <scp>A</scp>dverse <scp>L</scp>esions (<scp>REMOVAL</scp>): <scp>A</scp>n international multicentre trial. Diabetes, Obesity and Metabolism, 19(4), 509-516. Abstract.

Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn C, Shore A, Gates P, Palombo C, et al (2017). P19: Influence of Brachial Artery Stiffness on Flow-Mediated Dilatation in Healthy Young and Older Populations. Artery Research, 20(1), 98-98.

Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn C, Shore A, Gates P, Palombo C, et al (2017). P74: Wall Shear Rate and Brachial Artery Flow-Mediated Dilatory Response Between Healthy Young and Older Populations Using Multi-Gate Spectral Doppler Ultrasound. Artery Research, 20(1), 73-73.

Frost J, Ludeman L, Hillaby K, Gornall R, Lloyd G, Kendall C, Shore AC, Stone N (2017). Raman spectroscopy and multivariate analysis for the non invasive diagnosis of clinically inconclusive vulval lichen sclerosus. Analyst, 142(8), 1200-1206. Abstract. Author URL.

Old OJ, Lloyd GR, Nallala J, Isabelle M, Almond LM, Shepherd NA, Kendall CA, Shore AC, Barr H, Stone N, et al (2017). Rapid infrared mapping for highly accurate automated histology in Barrett's oesophagus. ANALYST, 142(8), 1227-1234. Author URL.

Smallwood MJ, Ble A, Melzer D, Winyard PG, Benjamin N, Shore AC, Gilchrist M (2017). Relationship Between Urinary Nitrate Excretion and Blood Pressure in the InChianti Cohort. Am J Hypertens, 30(7), 707-712. Abstract. Author URL.

Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, et al (2017). The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control. Cardiovasc Diabetol, 16(1). Abstract. Author URL.

Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, et al (2016). Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovasc Disord, 16(1). Abstract. Author URL.

Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn C, Shore A, Gates P, Palombo C, et al (2016). Brachial artery flow-mediated dilatation: different patterns of wall shear rate increase during reactive hyperaemia. Artery Research, 16(C), 67-68.

Iyengar SS, Morgan-Hughes G, Ukoumunne O, Clayton B, Davies EJ, Nikolaou V, Hyde CJ, Shore AC, Roobottom CA (2016). Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients. Clin Radiol, 71(2), 151-158. Abstract. Author URL.

Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE (2016). Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke. Ultrasound Med Biol, 42(5), 1130-1137. Abstract. Author URL.

Shepherd AI, Wilkerson DP, Fulford J, Winyard PG, Benjamin N, Shore AC, Gilchrist M (2016). Effect of nitrate supplementation on hepatic blood flow and glucose homeostasis: a double-blind, placebo-controlled, randomized control trial. Am J Physiol Gastrointest Liver Physiol, 311(3), G356-G364. Abstract. Author URL.

Frost J, Ludeman L, Hillaby K, Gornall R, Lloyd G, Kendall C, Shore AC, Stone N (2016). Identification of cancer associated molecular changes in histologically benign vulval disease found in association with vulval squamous cell carcinoma using Fourier transform infrared spectroscopy. Analytical Methods, 8(48), 8452-8460. Abstract.

Clark CE, Taylor RS, Butcher I, Stewart MC, Price J, Fowkes FGR, Shore AC, Campbell JL (2016). Inter-arm blood pressure difference and mortality: a cohort study in an asymptomatic primary care population at elevated cardiovascular risk. Br J Gen Pract, 66(646), e297-e308. Abstract. Author URL.

Elyas S, Shore AC, Kingwell H, Keenan S, Boxall L, Stewart J, James MA, Strain WD (2016). Microalbuminuria could improve risk stratification in patients with TIA and minor stroke. Ann Clin Transl Neurol, 3(9), 678-683. Abstract. Author URL.

Clark CE, Taylor RS, Shore AC, Campbell JL (2016). Prevalence of systolic inter-arm differences in blood pressure for different primary care populations: systematic review and meta-analysis. Br J Gen Pract, 66(652), e838-e847. Abstract. Author URL.

Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE (2016). Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation. Physiol Rep, 4(12). Abstract. Author URL.

Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, et al (2016). Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem, 291(19), 10210-10227. Abstract. Author URL.

Thorn CE, Shore AC (2016). The role of perfusion in the oxygen extraction capability of skin and skeletal muscle. Am J Physiol Heart Circ Physiol, 310(10), H1277-H1284. Abstract. Author URL.

Aizawa K, Casanova F, Mawson D, Elyas S, Adingupu DD, Gooding KM, Strain WD, Park CM, Parker KH, Gates PE, et al (2016). [PP.11.05] RESERVOIR-PRESSURE ANALYSIS IN TYPE 2 DIABETES INDIVIDUALS WITH CARDIOVASCULAR DISEASE. Journal of Hypertension, 34(Supplement 2), e178-e178.

Clark C, Shore A, Taylor R, Campbell J (2015). 1C.08: THE INTER-ARM DIFFERENCE IN BLOOD PRESSURE AND MORTALITY: SYSTEMATIC REVIEW AND META-ANALYSIS. J Hypertens, 33 Suppl 1 Abstract. Author URL.

Siervo M, Lara J, Jajja A, Sutyarjoko A, Ashor AW, Brandt K, Qadir O, Mathers JC, Benjamin N, Winyard PG, et al (2015). Ageing modifies the effects of beetroot juice supplementation on 24-hour blood pressure variability: an individual participant meta-analysis. Nitric Oxide, 47, 97-105. Abstract. Author URL.

Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW, et al (2015). Blood Oxygen Saturation After Ischemia is Altered with Abnormal Microvascular Reperfusion. Microcirculation, 22(4), 294-305. Abstract. Author URL.

Elyas S, Adingupu D, Aizawa K, Shore AC, Strain WD, Gates PE (2015). Cerebral hemodynamics in patients with large vessel disease stroke and lacunar stroke. INTERNATIONAL JOURNAL OF STROKE, 10, 368-368. Author URL.

Shepherd AI, Gilchrist M, Winyard PG, Jones AM, Hallmann E, Kazimierczak R, Rembialkowska E, Benjamin N, Shore AC, Wilkerson DP, et al (2015). Effects of dietary nitrate supplementation on the oxygen cost of exercise and walking performance in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled crossover trial. Free Radic Biol Med, 86, 200-208. Abstract. Author URL.

Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, et al (2015). Elevated Plasma Levels of MMP-12 Are Associated with Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects with Type 2 Diabetes. Arterioscler Thromb Vasc Biol, 35(7), 1723-1731. Abstract. Author URL.

Lewandowski AJ, Davis EF, Yu G, Digby JE, Boardman H, Whitworth P, Singhal A, Lucas A, Mccormick K, Shore AC, et al (2015). Elevated blood pressure in preterm-born offspring associates with a distinct antiangiogenic state and microvascular abnormalities in adult life. Hypertension, 65(3), 607-614. Abstract.

Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. Journal of Internal Medicine, 278(3), 291-302. Abstract.

Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, et al (2015). Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study. J Intern Med, 278(3), 291-302. Abstract. Author URL.

Aizawa. K, Casanova F, Mawson D, Elyas S, Adingupu D, Gooding K, Strain D, Shore A, Gates P (2015). P3.5 TYPE 2 DIABETES EXACERBATES CAROTID ARTERY ECHOGENICITY AND CENTRAL ARTERY STIFFNESS IN MIDDLE-AGED AND OLDER INDIVIDUALS. Artery Research, 12(C), 11-11.

Shepherd AI, Wilkerson DP, Dobson L, Kelly J, Winyard PG, Jones AM, Benjamin N, Shore AC, Gilchrist M (2015). The effect of dietary nitrate supplementation on the oxygen cost of cycling, walking performance and resting blood pressure in individuals with chronic obstructive pulmonary disease: a double blind placebo controlled, randomised control trial. Nitric Oxide, 48, 31-37. Abstract. Author URL.

Gilchrist M, Winyard PG, Fulford J, Anning C, Shore AC, Benjamin N (2014). Dietary nitrate supplementation improves reaction time in type 2 diabetes: development and application of a novel nitrate-depleted beetroot juice placebo. Nitric Oxide, 40, 67-74. Abstract. Author URL.

Pienaar PR, Micklesfield LK, Gill JMR, Shore AC, Gooding KM, Levitt NS, Lambert EV (2014). Ethnic differences in microvascular function in apparently healthy South African men and women. Experimental Physiology, 99(7), 985-994. Abstract.

Pienaar PR, Micklesfield LK, Levitt NS, Gooding K, Shore AC, Goedecke JH, Gill JMR, Lambert EV (2014). Insulin Resistance is Associated with Lower Acetylcholine-Induced Microvascular Reactivity in Nondiabetic Women. Metabolic Syndrome and Related Disorders, 12(3), 178-184. Abstract.

Clark CE, Steele AM, Taylor RS, Shore AC, Ukoumunne OC, Campbell JL (2014). Interarm Blood Pressure Difference in People with Diabetes: Measurement and Vascular and Mortality Implications a Cohort Study. DIABETES CARE, 37(6), 1613-1620. Author URL.

Aizawa K, Elyas S, Adingpu D, Shore A, Strain D, Gates P (2014). P3.10 REACTIVITY TO LOW-FLOW IN THE BRACHIAL ARTERY: a POTENTIAL DETERMINANT FOR FLOW-MEDIATED DILATORY RESPONSE. Artery Research, 8(4), 138-138.

Ripley DP, Kannoly S, Gosling OE, Hossain E, Chawner RR, Moore J, Shore AC, Bellenger NG (2014). Safety and feasibility of dobutamine stress cardiac magnetic resonance for cardiovascular assessment prior to renal transplantation. J Cardiovasc Med (Hagerstown), 15(4), 288-294. Abstract. Author URL.

Ripley DP, Gosling OE, Bhatia L, Peebles CR, Shore AC, Curzen N, Bellenger NG (2014). The relationship between the contralateral collateral supply and myocardial viability on cardiovascular magnetic resonance: can the angiogram predict functional recovery?. International Journal of Cardiology

Gurung A, Mazzaro L, Gates PE, Strain D, Shore AC, Shandas R (2013). Abstract 246: Echo Particle Image Velocimetry Generates Wall Shear Stress Biomarkers with Higher Accuracy than Doppler: Clinical Studies on 24 Healthy and 12 Tia Subjects. Arteriosclerosis Thrombosis and Vascular Biology, 33(suppl_1).

Strain WD, Hughes AD, Mayet J, Wright AR, Kooner J, Chaturvedi N, Shore AC (2013). Attenuated systemic microvascular function in men with coronary artery disease is associated with angina but not explained by atherosclerosis. Microcirculation, 20(7), 670-677. Abstract. Author URL.

Gosling O, Morgan-Hughes G, Iyengar S, Strain W, Loader R, Shore A, Roobottom C (2013). Computed tomography to diagnose coronary artery disease: a reduction in radiation dose increases applicability. Clinical Radiology, 68(4), 340-345. Abstract.

Blake E, Allen J, Thorn C, Shore A, Curnow A (2013). Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy. Lasers in Medical Science, 28(3), 997-1005. Abstract.

Gilchrist M, Winyard PG, Aizawa K, Anning C, Shore A, Benjamin N (2013). Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes. Free Radic Biol Med, 60, 89-97. Abstract. Author URL.

Aizawa K, Elyas S, Adingupu DD, Shore AC, Strain WD, Gates PE (2013). P2.17 ECHOGENICITY OF THE COMMON CAROTID ARTERY INTIMA-MEDIA COMPLEX IN STROKE. Artery Research, 7(3-4), 123-123.

Alkhouli N, Mansfield J, Green E, Bell J, Knight B, Liversedge N, Tham JC, Welbourn R, Shore AC, Kos K, et al (2013). The mechanical properties of human adipose tissues and their relationships to the structure and composition of the extracellular matrix. Am J Physiol Endocrinol Metab, 305(12), E1427-E1435. Abstract. Author URL.

Gooding KM, Shore AC, von Lany H, Ling R, Mitra M, Ball CI, Mawson D, Tooke JE (2012). Are features of the metabolic syndrome associated with macular thickness in individuals without diabetes mellitus?. Clinical and Experimental Ophthalmology, 3, 7-7.

Campbell J, Clark CE, Taylor RS, Shore AC, Ukoumunne OC (2012). Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta analysis. Lancet

Clark CE, Taylor RS, Shore AC, Ukoumunne OC, Campbell JL (2012). Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta-analysis (vol 379, pg 905, 2012). LANCET, 380(9838), 218-218. Author URL.

Vink H, Hubble S, Wijnands KA, Thorn C, Mawson D, Roos S, Poeze M, Shore A (2012). CLINICAL ASSESSMENT OF THE ENDOTHELIAL GLYCOCALYX TO MONITOR VASCULAR DYSFUNCTION IN SEPTIC SHOCK PATIENTS. INTENSIVE CARE MEDICINE, 38, S227-S227. Author URL.

Clark CE, Taylor RS, Shore AC, Ukoumunne OC, Campbell JL (2012). Erratum: Association of a diff erence in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta-analysis (The Lancet (2012) 379 (905-914). The Lancet, 380(9838).

Mahadavan L, Loktionov A, Daniels IR, Shore A, Cotter D, Llewelyn AH, Hamilton W (2012). Exfoliated colonocyte DNA levels and clinical features in the diagnosis of colorectal cancer: a cohort study in patients referred for investigation. Colorectal Dis, 14(3), 306-313. Abstract. Author URL.

Park C, Bathula R, Shore AC, Tillin T, Strain WD, Chaturvedi N, Hughes AD (2012). Impaired post-ischaemic microvascular hyperaemia in Indian Asians is unexplained by diabetes or other cardiovascular risk factors. Atherosclerosis, 221(2), 503-507. Abstract. Author URL.

Clark CE, Taylor RS, Shore AC, Ukoumunne OC, Campbell JL (2012). Interarm blood pressure difference and vascular disease Reply. LANCET, 380(9836), 24-25. Author URL.

Strain WD, Adingupu DD, Shore AC (2012). Microcirculation on a large scale: techniques, tactics and relevance of studying the microcirculation in larger population samples. Microcirculation, 19(1), 37-46. Abstract. Author URL.

Aizawa K, Elyas S, Adingupu DD, Shore AC, Strain WD, Gates PE (2012). P4.17 INFLUENCE OF ESTIMATED WALL SHEAR RATE INDICES ON CAROTID ARTERY INTIMA-MEDIA THICKNESS AND INTIMA-MEDIA COMPLEX ECHOGENICITY. Artery Research, 6(4), 188-188.

Lazdam M, de la Horra A, Diesch J, Francis J, Kenworthy Y, Shore A, Neubauer S, Kharbanda R, Alp N, Redman C, et al (2012). PP032. Unique features of long-term cardiovascular phenotype in young women with early-onset pre-eclampsia. Pregnancy Hypertens, 2(3), 259-260. Abstract. Author URL.

Veeramootoo D, Shore AC, Wajed SA (2012). Randomized controlled trial of laparoscopic gastric ischemic conditioning prior to minimally invasive esophagectomy, the LOGIC trial. Surg Endosc, 26(7), 1822-1829. Abstract. Author URL.

Chaturvedi N, Bathula R, Shore AC, Panerai R, Potter J, Kooner J, Chambers J, Hughes AD (2012). South Asians Have Elevated Postexercise Blood Pressure and Myocardial Oxygen Consumption Compared to Europeans Despite Equivalent Resting Pressure. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 1(5). Author URL.

Clark CE, Taylor RS, Shore AC, Campbell JL (2012). The difference in blood pressure readings between arms and survival: primary care cohort study. BMJ, 344 Abstract. Author URL.

Lazdam M, De La Horra A, Diesch J, Kenworthy Y, Davis E, Lewandowski AJ, Szmigielski C, Shore A, MacKillop L, Kharbanda R, et al (2012). Unique blood pressure characteristics in mother and offspring after early onset preeclampsia. Hypertension, 60(5), 1338-1345. Abstract.

Wajed SA, Veeramootoo D, Shore AC (2012). Video. Surgical optimisation of the gastric conduit for minimally invasive oesophagectomy. Surg Endosc, 26(1), 271-276. Abstract. Author URL.

Thorn CE, Kyte H, Slaff DW, Shore AC (2011). An association between vasomotion and oxygen extraction. Am J Physiol Heart Circ Physiol, 301(2), H442-H449. Abstract. Author URL.

Aizawa K, Gates PE, Strain WD, Gosling OE, Mazzaro L, Zhang F, Barker AJ, Fulford J, Shore AC, Bellenger NG, et al (2011). Arterial Wall Shear Stress Measurement in Vivo Using Echo Particle Image Velocimetry (Echo PIV). MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 43(5), 743-744. Author URL.

Zhang F, Lanning C, Mazzaro L, Barker AJ, Gates PE, Strain WD, Fulford J, Gosling OE, Shore AC, Bellenger NG, et al (2011). In vitro and preliminary in vivo validation of echo particle image velocimetry in carotid vascular imaging. Ultrasound Med Biol, 37(3), 450-464. Abstract. Author URL.

Gilchrist M, Shore AC, Benjamin N (2011). Inorganic nitrate and nitrite and control of blood pressure. Cardiovasc Res, 89(3), 492-498. Abstract. Author URL.

Wilkerson DP, Poole DC, Jones AM, Fulford J, Mawson DM, Ball CI, Shore AC (2011). Older type 2 diabetic males do not exhibit abnormal pulmonary oxygen uptake and muscle oxygen utilization dynamics during submaximal cycling exercise. Am J Physiol Regul Integr Comp Physiol, 300(3), R685-R692. Abstract.

Aizawa K, Elyas S, D’Abate F, Majekolagbe D, Shore AC, Strain WD, Gates PE (2011). P8.08 THE RELATIONSHIP BETWEEN BRACHIAL ARTERY FLOW-MEDIATED DILATION AND SHEAR RATE IN INDIVIDUALS WITH INCREASED CARDIOVASCULAR RISK. Artery Research, 5(4), 184-184.

Bathula R, Hughes AD, Panerai RB, Potter JF, McG Thom SA, Tillin T, Shore AC, Hale R, Chambers J, Kooner J, et al (2011). South Asians have adverse cerebrovascular haemodynamics, despite equivalent blood pressure, compared with Europeans. This is due to their greater hyperglycaemia. Int J Epidemiol, 40(6), 1490-1498. Abstract. Author URL.

Whiteman M, Gooding KM, Whatmore JL, Ball CI, Mawson D, Skinner K, Tooke JE, Shore AC (2010). Adiposity is a major determinant of plasma levels of the novel vasodilator hydrogen sulphide. Diabetologia, 53(8), 1722-1726. Abstract. Author URL.

Strain WD, Elyas S, Gates PE, Shore AC (2010). Age-related change in endothelial and microvessel function and therapeutic consequences. Reviews in Clinical Gerontology, 20(3), 161-170. Abstract.

Strain WD, Shore AC, Melzer D (2010). Albumin:creatinine ratio predicts mortality after stroke: analysis of the Third National Health and Nutrition Examination Survey. J Am Geriatr Soc, 58(12), 2434-2435. Author URL.

Strain WD, Chaturvedi N, Hughes A, Nihoyannopoulos P, Bulpitt CJ, Rajkumar C, Shore AC (2010). Associations between cardiac target organ damage and microvascular dysfunction: the role of blood pressure. J Hypertens, 28(5), 952-958. Abstract. Author URL.

Strain WD, Hughes AD, Mayet J, Wright AR, Kooner J, Chaturvedi N, Shore AC (2010). Attenuation of microvascular function in those with cardiovascular disease is similar in patients of Indian Asian and European descent. BMC Cardiovasc Disord, 10 Abstract. Author URL.

Gooding KM, Tooke JE, von Lany H, Mitra M, Ling R, Ball CI, Mawson D, Skinner K, Shore AC (2010). Capillary pressure may predict preclinical changes in the eye. Diabetologia, 53(9), 2029-2035. Abstract. Author URL.

Whiteman M, Haigh R, Tarr JM, Gooding KM, Shore AC, Winyard PG (2010). Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation. Ann N Y Acad Sci, 1203, 146-150. Abstract. Author URL.

Bathula R, Hughes AD, Panerai R, Potter J, McG. Thom SA, Francis DP, Shore AC, Kooner J, Chaturvedi N (2010). Indian Asians have poorer cardiovascular autonomic function than Europeans: This is due to greater hyperglycaemia and may contribute to their greater risk of heart disease. Diabetologia, 53(10), 2120-2128. Abstract.

Veeramootoo D, Shore AC, Shields B, Krishnadas R, Cooper M, Berrisford RG, Wajed SA (2010). Ischemic conditioning shows a time-dependant influence on the fate of the gastric conduit after minimally invasive esophagectomy. Surg Endosc, 24(5), 1126-1131. Abstract. Author URL.

Gates PE, Strain WD, Shore AC (2009). Human endothelial function and microvascular ageing. Exp Physiol, 94(3), 311-316. Abstract. Author URL.

Thorn CE, Matcher SJ, Meglinski IV, Shore AC (2009). Is mean blood saturation a useful marker of tissue oxygenation?. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 296(5), H1289-H1295. Author URL.

Hubble SMA, Kyte HL, Gooding K, Shore AC (2009). Variability in sublingual microvessel density and flow measurements in healthy volunteers. Microcirculation, 16(2), 183-191. Abstract. Author URL.

McHarg S, Shore AC, Whatmore JL (2008). Heterogeneity of phospholipase D activation by angiotensin II, lysophosphatidylcholine, and insulin in human endothelial cells. Endothelium, 15(4), 213-218. Abstract. Author URL.

Lonnen KF, Powell RJ, Taylor D, Shore AC, MacLeod KM (2008). Road traffic accidents and diabetes: insulin use does not determine risk. Diabet Med, 25(5), 578-584. Abstract. Author URL.

Tillin T, Dhutia H, Chambers J, Malik I, Coady E, Mayet J, Wright AR, Kooner J, Shore A, Thom S, et al (2008). South Asian men have different patterns of coronary artery disease when compared with European men. Int J Cardiol, 129(3), 406-413. Abstract. Author URL.

Chaturvedi N, Coady E, Mayet J, Wright AR, Shore AC, Byrd S, McG Thom SA, Kooner JS, Schalkwijk CG, Hughes AD, et al (2007). Indian Asian men have less peripheral arterial disease than European men for equivalent levels of coronary disease. Atherosclerosis, 193(1), 204-212. Abstract. Author URL.

Tillin T, Chambers J, Malik I, Coady E, Byrd S, Mayet J, Wright AR, Kooner J, Shore A, Thom S, et al (2007). Measurement of pulse wave velocity: site matters. J Hypertens, 25(2), 383-389. Abstract. Author URL.

Dotsenko O, Chaturvedi N, Thom SAM, Wright AR, Mayet J, Shore A, Schalkwijk C, Hughes AD (2007). Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men. J Thromb Haemost, 5(10), 2036-2042. Abstract. Author URL.

Hughes AD, Coady E, Raynor S, Mayet J, Wright AR, Shore AC, Kooner JS, Thom SAM, Chaturvedi N (2007). Reduced endothelial progenitor cells in European and South Asian men with atherosclerosis. Eur J Clin Invest, 37(1), 35-41. Abstract. Author URL.

Johnson P, Shore A, Potter J, Panerai R, James M (2006). Baroreflex sensitivity measured by spectral and sequence analysis in cerebrovascular disease : methodological considerations. Clin Auton Res, 16(4), 270-275. Abstract. Author URL.

DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial Investigators, Gerstein HC, Yusuf S, Bosch J, Pogue J, Sheridan P, Dinccag N, Hanefeld M, Hoogwerf B, Laakso M, et al (2006). Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet, 368(9541), 1096-1105. Abstract. Author URL.

AShore, Hemsley A, James M, Tullet J (2006). Effects of Aging and Hypertension on the Microcirculation. Hypertension, 47(5), 968-974.

James MA, Tullett J, Hemsley AG, Shore AC (2006). Effects of aging and hypertension on the microcirculation. Hypertension, 47(5), 968-974. Abstract. Author URL.

Strain D, Chaturvedi N, Dockery F, Shiff R (2006). Increased arterial stiffness in Europeans and African Caribbeans with type 2 diabetes cannot be accounted for by conventional cardiovascular risk factors. American Journal of Hypertension, 19(9), 889-896.

Whatmore JL, Konopatskaya O, Shore AC (2006). Lysophosphatidylcholine stimulation of CGMP production in human endothelial cells involves tyrosine kinases, heterotrimeric GTP binding proteins, phosphatidylinositol 3-kinase and protein kinase C. Vascular Pharmacology, 45(3), e142-e143.

Gooding KM, Hannemann MM, Tooke JE, Clough GF, Shore AC (2006). Maximum skin hyperaemia induced by local heating: possible mechanisms. J Vasc Res, 43(3), 270-277. Abstract. Author URL.

Middlebrooke AR, Elston LM, Macleod KM, Mawson DM, Ball CI, Shore AC, Tooke JE (2006). Six months of aerobic exercise does not improve microvascular function in type 2 diabetes mellitus. Diabetologia, 49(10), 2263-2271. Abstract. Author URL.

Tooke JE, Elston LM, Gooding KM, Ball CI, Mawson DM, Piper J, Sriraman R, Urquhart R, Shore AC (2006). The insulin sensitiser pioglitazone does not influence skin microcirculatory function in patients with type 2 diabetes treated with insulin. Diabetologia, 49(5), 1064-1070. Abstract. Author URL.

Konopatskaya O, Shore AC, Tooke JE, Whatmore JL (2005). A role for heterotrimeric GTP-binding proteins and ERK1/2 in insulin-mediated, nitric-oxide-dependent, cyclic GMP production in human umbilical vein endothelial cells. Diabetologia, 48(3), 595-604. Abstract. Author URL.

Strain WD, Chaturvedi N, Bulpitt CJ, Rajkumar C, Shore AC (2005). Albumin excretion rate and cardiovascular risk: could the association be explained by early microvascular dysfunction?. Diabetes, 54(6), 1816-1822. Abstract. Author URL.

Strain D, Bulpitt C, Chaturvedi N, Nihoyannopoulos P (2005). Differences in the association between type 2 diabetes and impaired microvascular function among Europeans and African Caribbeans. Diabetologia, 48(11), 2269-2277.

Middlebrooke AR, Armstrong N, Welsman JR, Shore AC, Clark P, MacLeod KM (2005). Does aerobic fitness influence microvascular function in healthy adults at risk of developing Type 2 diabetes?. Diabet Med, 22(4), 483-489. Abstract. Author URL.

Strain WD, Chaturvedi N, Shore A, Cruickshank JK, Heagerty AM (2005). Ethnic differences in microvascular structure and function [3] (multiple letters). Journal of Hypertension, 23(7), 1434-1436.

Strain D, Chaturvedi N, Leggetter S, Nihoyannopoulos P (2005). Ethnic differences in skin microvascular function and their relation to cardiac target-organ damage. Journal of Hypertension, 23(1), 133-140.

Gooding KM, MacLeod KM, Spyer G, Ewings P, Tooke JE, Shore AC (2005). Impact of hormone replacement therapy on microvascular function in healthy and Type 2 diabetic postmenopausal women. Diabet Med, 22(5), 536-542. Abstract. Author URL.

Hannemann M, Mawson D, Shore A (2005). Letter to the editor. Diabetes and Vascular Disease Research, 2(2), 94-95.

Fegan PG, Shore AC, Mawson D, Tooke JE, MacLeod KM (2005). Microvascular endothelial function in subjects with Type 2 diabetes and the effect of lipid-lowering therapy. Diabet Med, 22(12), 1670-1676. Abstract. Author URL.

Moger J, Winlove, C.P. Matcher, S.J. (2005). The Effect of Multiple Scattering upon Velocity Profiles Measured using Doppler OCT. Journal of Physics D: Applied Physics, 38(15), 2597-2605.

Moger J, Winlove CP, Shore AC, Matcher SJ (2005). The effect of multiple scattering upon velocity profiles measured using doppler OCT. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 5861, 1-12. Abstract.

Shore A (2004). Book Review Diabetes and Cardiovascular Disease: Integrating Science and Clinical Medicine Edited by Steven P. Marso and David M. Stern. 527 pp. illustrated. Philadelphia, Lippincott Williams & Wilkins, 2004. $99.95. 0-7817-4053-3. N Engl J Med, 351(18), 1918-1919. Abstract.

Irving RJ, Shore AC, Belton NR, Elton RA, Webb DJ, Walker BR (2004). Low birth weight predicts higher blood pressure but not dermal capillary density in two populations. Hypertension, 43(3), 610-613. Abstract. Author URL.

Moger J, Matcher SJ, Winlove CP, Shore A (2004). Measuring red blood cell flow dynamics in a glass capillary using Doppler optical coherence tomography and Doppler amplitude optical coherence tomography. J Biomed Opt, 9(5), 982-994. Abstract. Author URL.

Barker AL, Konopatskaya O, Neal CR, Macpherson JV, Whatmore JL, Winlove CP, Unwin PR, Shore AC (2004). Observation and characterisation of the glycocalyx of viable human endothelial cells using confocal laser scanning microscopy. Physical Chemistry Chemical Physics, 1006-1011. Abstract.

Chaturvedi N, Rajkumar C, Strain WD, Nihoyannopoulos P, Shore AC, Bulpitt CJ (2004). P-440: Ethnic differences in central and augmentation index; do they account for differing susceptibility to left ventricular hypertrophy. American Journal of Hypertension, 17(S1), 195a-195a.

Gooding KM, Whatmore JL, Warland D, Hannemann MM, Middlebrooke AR, Paisley K, Liddell W, Lee B, Tooke JE, Shore AC, et al (2004). PC21 PREDICTORS OF SKIN MINIMUM VASCULAR RESISTANCE IN WOMEN. Microcirculation, 11(6), 545-546.

McHarg S, Shore AC, Whatmore JL (2004). PC47 LACK OF ACTIVATION OF PHOSPHOLIPASE D BY ENDOTHELIN-1 AND ANGIOTENSIN II IN HUMAN ENDOTHELIAL CELLS. Microcirculation, 11(6), 554-554.

Hahn M, Jünger M, Shore AC (2004). The effect of prostaglandin E1 on nailfold capillary blood pressure and red blood cell velocity in humans. Clin Hemorheol Microcirc, 31(3), 227-234. Abstract. Author URL.

Fegan PG, Tooke JE, Gooding KM, Tullett JM, MacLeod KM, Shore AC (2003). Capillary pressure in subjects with type 2 diabetes and hypertension and the effect of antihypertensive therapy. Hypertension, 41(5), 1111-1117. Abstract. Author URL.

Paisley KE, Beaman M, Tooke JE, Mohamed-Ali V, Lowe GDO, Shore AC (2003). Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney Int, 63(2), 624-633. Abstract. Author URL.

Konopatskaya O, Whatmore JL, Tooke JE, Shore AC (2003). Insulin and lysophosphatidylcholine synergistically stimulate NO-dependent cGMP production in human endothelial cells. Diabet Med, 20(10), 838-845. Abstract. Author URL.

Shore AC, Evans JC, Frayling TM, Clark PM, Lee BC, Horikawa Y, Hattersley AT, Tooke JE (2002). Association of calpain-10 gene with microvascular function. Diabetologia, 45(6), 899-904. Abstract. Author URL.

Irving RJ, Walker BR, Noon JP, Watt GCM, Webb DJ, Shore AC (2002). Microvascular correlates of blood pressure, plasma glucose, and insulin resistance in health. Cardiovasc Res, 53(1), 271-276. Abstract. Author URL.

Walker BR, Shore AC (2002). Reply to letter to the editor. CARDIOVASCULAR RESEARCH, 55(2), 420-421. Author URL.

Shore AC (2002). The microvasculature in type 1 diabetes. Semin Vasc Med, 2(1), 9-20. Abstract. Author URL.

Hannemann MM, Liddell WG, Shore AC, Clark PM, Tooke JE (2002). Vascular function in women with previous gestational diabetes mellitus. J Vasc Res, 39(4), 311-319. Abstract. Author URL.

Fegan PG, Macleod KM, Tooke JE, Shore AC (2002). n-3 NEFA: vascular implications. Eur Heart J, 23(3), 185-187. Author URL.

Goh KL, Shore AC, Quinn M, Tooke JE (2001). Impaired microvascular vasodilatory function in 3-month-old infants of low birth weight. Diabetes Care, 24(6), 1102-1107. Abstract. Author URL.

Lee BC, Shore AC, Humphreys JM, Lowe GD, Rumley A, Clark PM, Hattersley AT, Tooke JE (2001). Skin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes. Diabet Med, 18(7), 541-545. Abstract. Author URL.

Shore AC (2000). Capillaroscopy and the measurement of capillary pressure. Br J Clin Pharmacol, 50(6), 501-513. Abstract. Author URL.

Kernick DP, Shore AC (2000). Characteristics of laser Doppler perfusion imaging in vitro and in vivo. Physiol Meas, 21(2), 333-340. Abstract. Author URL.

Hamid S, Klaentschi K, Shore AC, Tooke JE (1999). A modified diffusion chamber to study the effect of hydrostatic pressure on fluid permeability. JOURNAL OF VASCULAR RESEARCH, 36(4), 336-337. Author URL.

Lee BC, Appleton M, Shore AC, Tooke JE, Hattersley AT (1999). Impaired maximum microvascular hyperaemia in patients with MODY 3 (hepatocyte nuclear factor-1alpha gene mutations). Diabet Med, 16(9), 731-735. Abstract. Author URL.

Klaentschi K, Shore AC, Tooke JE, Brown JA (1999). Pressure-permeability relationships in crosslinked basement membranes. Microvasc Res, 58(3), 329-332. Author URL.

Kernick DP, Tooke JE, Shore AC (1999). The biological zero signal in laser Doppler fluximetry - origins and practical implications. Pflugers Arch, 437(4), 624-631. Abstract. Author URL.

Taylor RS, Stockman J, Kernick D, Reinhold D, Shore AC, Tooke JE (1998). Ambulatory blood pressure monitoring for hypertension in general practice. J R Soc Med, 91(6), 301-304. Abstract. Author URL.

Mawson DM, Shore AC (1998). Comparison of CapiFlow and frame by frame analysis for the assessment of capillary red blood cell velocity. J Med Eng Technol, 22(2), 53-63. Abstract. Author URL.

Klaentschi K, Tooke JE, Shore AC (1998). Effect of increased pressure on microvascular endothelial cell growth. JOURNAL OF VASCULAR RESEARCH, 35(3), 226-227. Author URL.

Turner RC, Holman RR, Cull CA, Stratton IM, Matthews DR, Frighi V, Manley SE, Neil A, McElroy K, Wright D, et al (1998). Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). LANCET, 352(9131), 837-853. Author URL.

Klaentschi K, Brown JA, Niblett PG, Shore AC, Tooke JE (1998). Pressure-permeability relationships in basement membrane: Effects of static and dynamic pressures. American Journal of Physiology - Heart and Circulatory Physiology, 274(4 43-4). Abstract.

Klaentschi K, Brown JA, Niblett PG, Shore AC, Tooke JE (1998). Pressure-permeability relationships in basement membrane: effects of static and dynamic pressures. Am J Physiol, 274(4), H1327-H1334. Abstract. Author URL.

Lewis DM, Bradwell AR, Shore AC, Beaman M, Tooke JE (1997). Capillary filtration coefficient and urinary albumin leak at altitude. Eur J Clin Invest, 27(1), 64-68. Abstract. Author URL.

Kunzek S, Quinn MW, Shore AC (1997). Does change in skin perfusion provide a good index to monitor the sympathetic response to a noxious stimulus in preterm newborns?. Early Hum Dev, 49(2), 81-89. Abstract. Author URL.

Noon JP, Walker BR, Webb DJ, Shore AC, Holton DW, Edwards HV, Watt GC (1997). Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure. J Clin Invest, 99(8), 1873-1879. Abstract. Author URL.

Jaap AJ, Shore AC, Tooke JE (1997). Relationship of insulin resistance to microvascular dysfunction in subjects with fasting hyperglycaemia. Diabetologia, 40(2), 238-243. Abstract. Author URL.

Tooke JE, Shore AC, Cohen RA, Kluft C (1996). Diabetic angiopathy: tracking down the culprits. J Diabetes Complications, 10(3), 173-181. Author URL.

Jaap AJ, Shore AC, Tooke JE (1996). Differences in microvascular fluid permeability between long-duration type I (insulin-dependent) diabetic patients with and without significant microangiopathy. Clin Sci (Lond), 90(2), 113-117. Abstract. Author URL.

Mahy IR, Lewis DM, Shore AC, Penney MD, Smith LD, Tooke JE (1996). Disturbance of peripheral microvascular fluid permeability by the onset of atrioventricular asynchrony in patients with programmable pacemakers. Heart, 75(5), 509-512. Abstract. Author URL.

Noon JP, Haynes WG, Webb DJ, Shore AC (1996). Local inhibition of nitric oxide generation in man reduces blood flow in finger pulp but not in hand dorsum skin. J Physiol, 490 ( Pt 2)(Pt 2), 501-508. Abstract. Author URL.

Hahn M, Klyscz T, Shore AC, Jünger M (1996). Newly developed software for capillary blood pressure analysis in microcirculatory research. Int J Microcirc Clin Exp, 16(3), 129-136. Abstract. Author URL.

Morris SJ, Shore AC (1996). Skin blood flow responses to the iontophoresis of acetylcholine and sodium nitroprusside in man: possible mechanisms. J Physiol, 496 ( Pt 2)(Pt 2), 531-542. Abstract. Author URL.

Jaap AJ, Shore AC, Stockman AJ, Tooke JE (1996). Skin capillary density in subjects with impaired glucose tolerance and patients with type 2 diabetes. Diabet Med, 13(2), 160-164. Abstract. Author URL.

Morris SJ, Kunzek S, Shore AC (1996). The effect of acetylcholine on finger capillary pressure and capillary flow in healthy volunteers. J Physiol, 494 ( Pt 1)(Pt 1), 307-313. Abstract. Author URL.

Mahy IR, Tooke JE, Shore AC (1995). Capillary pressure during and after incremental venous pressure elevation in man. J Physiol, 485 ( Pt 1)(Pt 1), 213-219. Abstract. Author URL.

Shore AC, Sandeman DD, Tooke JE (1995). Capillary pressure, pulse pressure amplitude, and pressure waveform in healthy volunteers. Am J Physiol, 268(1 Pt 2), H147-H154. Abstract. Author URL.

Mahy IR, Shore AC, Smith LD, Tooke JE (1995). Disturbance of peripheral microvascular function in congestive heart failure secondary to idiopathic dilated cardiomyopathy. Cardiovasc Res, 30(6), 939-944. Abstract. Author URL.

Jaap AJ, Pym CA, Seamark C, Shore AC, Tooke JE (1995). Microvascular function in type 2 (non-insulin-dependent) diabetes: improved vasodilation after one year of good glycaemic control. Diabet Med, 12(12), 1086-1091. Abstract. Author URL.

Mahy IR, Shore AC, Smith LD, Tooke JE (1995). Postural vasoconstrictor response in human heart failure. Int J Microcirc Clin Exp, 15(3), 137-142. Abstract. Author URL.

Morris SJ, Shore AC, Tooke JE (1995). Responses of the skin microcirculation to acetylcholine and sodium nitroprusside in patients with NIDDM. Diabetologia, 38(11), 1337-1344. Abstract. Author URL.

Jaap AJ, Shore AC, Gamble J, Gartside IB, Tooke JE (1994). Capillary filtration coefficient in type II (non-insulin-dependent) diabetes. J Diabetes Complications, 8(2), 111-116. Abstract. Author URL.

Shore AC, Jaap AJ, Tooke JE (1994). Capillary pressure in patients with NIDDM. Diabetes, 43(10), 1198-1202. Abstract. Author URL.

Mahy IR, Shore AC, Smith LD, Tooke JE (1994). Capillary pulse waveform in aortic stenosis. Int J Microcirc Clin Exp, 14(5), 257-261. Abstract. Author URL.

Shore AC, Tooke JE (1994). Microvascular function in human essential hypertension. J Hypertens, 12(7), 717-728. Author URL.

Flynn MD, Shore AC, Sandeman DE, Mawson D, Donohoe M, Tooke JE (1994). Oedema in patients with Addison's disease on replacement therapy: glucocorticoid excess and mineralocorticoid deficiency?. QJM, 87(7), 437-441. Abstract. Author URL.

Shore AC, Price KJ, Sandeman DD, Tripp JH, Tooke JE (1994). Posturally induced vasoconstriction in diabetes mellitus. Arch Dis Child, 70(1), 22-26. Abstract. Author URL.

Jaap AJ, Hammersley MS, Shore AC, Tooke JE (1994). Reduced microvascular hyperaemia in subjects at risk of developing type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia, 37(2), 214-216. Abstract. Author URL.

Hahn M, Shore AC (1994). The effect of rapid local cooling on human finger nailfold capillary blood pressure and blood cell velocity. J Physiol, 478 ( Pt 1)(Pt 1), 109-114. Abstract. Author URL.

Jaap AJ, Shore AC, Tooke JE (1994). The influence of hypertension on microvascular blood flow and resistance to flow in the skin of patients with type 2 (non-insulin-dependent) diabetes. Diabet Med, 11(9), 883-887. Abstract. Author URL.

Mahy IR, Shore AC, Smith LD, Tooke JE (1994). The peripheral microcirculation in atrial fibrillation: preservation of capillary pressure and filtration coefficient. Cardiovasc Res, 28(10), 1555-1558. Abstract. Author URL.

YOUMBISSI TJ, SELLARS L, SHORE AC, WILKINSON R (1993). BLOOD-PRESSURE, CHRONIC AMBULATORY PERITONEAL-DIALYSIS, AND HEMODIALYSIS - RELATIONSHIPS WITH SODIUM LOAD, PLASMA-RENIN ACTIVITY, AND ALDOSTERONE. SEMAINE DES HOPITAUX, 69(9), 243-247. Author URL.

Shore AC, Sandeman DD, Tooke JE (1993). Effect of an increase in systemic blood pressure on nailfold capillary pressure in humans. Am J Physiol, 265(3 Pt 2), H820-H823. Abstract. Author URL.

Jaap AJ, Shore AC, Gartside IB, Gamble J, Tooke JE (1993). Increased microvascular fluid permeability in young type 1 (insulin-dependent) diabetic patients. Diabetologia, 36(7), 648-652. Abstract. Author URL.

Spiegel M, Vesti B, Shore A, Franzeck UK, Becker F, Bollinger A (1992). Pressure of lymphatic capillaries in human skin. Am J Physiol, 262(4 Pt 2), H1208-H1210. Abstract. Author URL.

Sandeman DD, Shore AC, Tooke JE (1992). Relation of skin capillary pressure in patients with insulin-dependent diabetes mellitus to complications and metabolic control. N Engl J Med, 327(11), 760-764. Abstract. Author URL.

Flynn MD, Sandeman DD, Mawson DM, Shore AC, Tooke JE (1991). Cyclical hypothermia: successful treatment with ephedrine. J R Soc Med, 84(12), 752-753. Author URL.

Shore AC, Price KJ, Sandeman DD, Green EM, Tripp JH, Tooke JE (1991). Impaired microvascular hyperaemic response in children with diabetes mellitus. Diabet Med, 8(7), 619-623. Abstract. Author URL.

Sandeman DD, Pym CA, Green EM, Seamark C, Shore AC, Tooke JE (1991). Microvascular vasodilatation in feet of newly diagnosed non-insulin dependent diabetic patients. BMJ, 302(6785), 1122-1123. Author URL.

Shore AC, Markandu ND, MacGregor GA (1988). A randomized crossover study to compare the blood pressure response to sodium loading with and without chloride in patients with essential hypertension. J Hypertens, 6(8), 613-617. Abstract. Author URL.

Walter SJ, Shore AC, Shirley DG (1988). Effect of potassium depletion on renal tubular function in the rat. Clin Sci (Lond), 75(6), 621-628. Abstract. Author URL.

Shore AC, Markandu ND, Sagnella GA, Singer DR, Forsling ML, Buckley MG, Sugden AL, MacGregor GA (1988). Endocrine and renal response to water loading and water restriction in normal man. Clin Sci (Lond), 75(2), 171-177. Abstract. Author URL.

Sagnella GA, Markandu ND, Buckley MG, Shore AC, Sugden AL, Singer DR, MacGregor GA (1988). Plasma atrial natriuretic peptide in essential hypertension. Comparison with normotensive subjects and effects of changes in dietary sodium intake. Am J Hypertens, 1(2), 112-118. Abstract. Author URL.

Cappuccio FP, Markandu ND, Tucker FA, Shore AC, MacGregor GA (1987). A double-blind study of the blood pressure lowering effect of a thiazide diuretic in hypertensive patients already on nifedipine and a beta-blocker. J Hypertens, 5(6), 733-738. Abstract. Author URL.

Cappuccio FP, Markandu ND, Buckley MG, Sagnella GA, Shore AC, MacGregor GA (1987). Atrial natriuretic peptides and mineralocorticoid escape in man. Journal of Hypertension, 5(SUPPL. 5).

Singer DR, Markandu ND, Shore AC, MacGregor GA (1987). Captopril and nifedipine in combination for moderate to severe essential hypertension. Hypertension, 9(6), 629-633. Abstract. Author URL.

Cappuccio FP, Markandu ND, Buckley MG, Sagnella GA, Shore AC, MacGregor GA (1987). Changes in the plasma levels of atrial natriuretic peptides during mineralocorticoid escape in man. Clin Sci (Lond), 72(5), 531-539. Abstract. Author URL.

Singer DR, Shore AC, Markandu ND, Buckley MG, Sagnella GA, MacGregor GA (1987). Dissociation between plasma atrial natriuretic peptide levels and urinary sodium excretion after intravenous saline infusion in normal man. Clin Sci (Lond), 73(3), 285-289. Abstract. Author URL.

Cappuccio FP, Markandu ND, Singer DR, Smith SJ, Shore AC, MacGregor GA (1987). Does oral calcium supplementation lower high blood pressure? a double blind study. J Hypertens, 5(1), 67-71. Abstract. Author URL.

MacGregor GA, Markandu ND, Singer DR, Cappuccio FP, Shore AC, Sagnella GA (1987). Moderate sodium restriction with angiotensin converting enzyme inhibitor in essential hypertension: a double blind study. Br Med J (Clin Res Ed), 294(6571), 531-534. Abstract. Author URL.

Singer DR, Markandu ND, Shore AC, MacGregor GA (1987). Nifedipine and acebutolol in combination for the treatment of moderate to severe essential hypertension. J Hum Hypertens, 1(1), 31-37. Abstract. Author URL.

Sagnella GA, Markandu ND, Buckley MG, Singer DR, Sugden AL, Shore AC, MacGregor GA (1987). Plasma atrial natriuretic peptide in essential hypertension: effects of changes in dietary sodium. Br Med J (Clin Res Ed), 295(6595), 417-418. Author URL.

Sagnella GA, Markandu ND, Shore AC, Forsling ML, MacGregor GA (1987). Plasma atrial natriuretic peptide: its relationship to changes in sodium intake, plasma renin activity and aldosterone in man. Clin Sci (Lond), 72(1), 25-30. Abstract. Author URL.

Sagnella GA, Markandu ND, Shore AC, MacGregor GA (1987). Plasma immunoreactive atrial natriuretic peptide and changes in dietary sodium intake in man. Life Sci, 40(2), 139-143. Abstract. Author URL.

Shore AC, Booker J, Sagnella GA, Markandu ND, MacGregor GA (1987). Serum ionized calcium and pH: effects of blood storage, some physiological influences and a comparison between normotensive and hypertensive subjects. J Hypertens, 5(4), 499-505. Abstract. Author URL.

Innes JA, Mills CJ, Noble MI, Murphy K, Pugh S, Shore AC, Guz A (1987). Validation of beat by beat pulsed Doppler measurements of ascending aortic blood velocity in man. Cardiovasc Res, 21(1), 72-80. Abstract. Author URL.

Katoh Y, Kurosawa T, Takeda S, Kurokawa S, Sakamotom H, Marumo F, Kikawada R, Singer DRJ, Shore AC, Markandu ND, et al (1986). ATRIAL NATRIURETIC PEPTIDE LEVELS IN TREATED CONGESTIVE HEART FAILURE. The Lancet, 327(8485).

Cappuccio FP, Markandu ND, Beynon GW, Shore AC, MacGregor GA (1986). Effect of increasing calcium intake on urinary sodium excretion in normotensive subjects. Clin Sci (Lond), 71(4), 453-456. Abstract. Author URL.

Sagnella GA, Jones JC, Shore AC, Markandu ND, MacGregor GA (1986). Evidence for increased levels of a circulating ouabainlike factor in essential hypertension. Hypertension, 8(5), 433-437. Abstract. Author URL.

Sagnella GA, Markandu ND, Shore AC, MacGregor GA (1986). Raised circulating levels of atrial natriuretic peptides in essential hypertension. Lancet, 1(8474), 179-181. Abstract. Author URL.

Sagnella GA, Markandu ND, Shore AC, MacGregor GA (1985). Effects of changes in dietary sodium intake and saline infusion on immunoreactive atrial natriuretic peptide in human plasma. Lancet, 2(8466), 1208-1211. Abstract. Author URL.

Sagnella GA, Nolan DA, Shore AC, MacGregor GA (1985). Effects of synthetic atrial natriuretic peptides on sodium-potassium transport in human erythrocytes. Clin Sci (Lond), 69(2), 223-226. Abstract. Author URL.

Cappuccio FP, Markandu ND, Beynon GW, Shore AC, Sampson B, MacGregor GA (1985). Lack of effect of oral magnesium on high blood pressure: a double blind study. Br Med J (Clin Res Ed), 291(6490), 235-238. Abstract. Author URL.

Shore AC, Beynon GW, Jones JC, Markandu ND, Sagnella GA, MacGregor GA (1985). Mononuclear leucocyte intracellular free calcium--does it correlate with blood pressure?. J Hypertens, 3(2), 183-188. Abstract. Author URL.

Sellars L, Shore AC, Wilkinson R (1985). Renal vein renin studies in renovascular hypertension--do they really help?. J Hypertens, 3(2), 177-181. Abstract. Author URL.

Sellars L, Shore AC, Wilkinson R (1985). Reply by author's. Journal of Hypertension, 3(6), 659-660.

Sellars L, Shore AC, Mott V, Wilkinson R (1985). The renin-angiotensin-aldosterone system in decompensated cirrhosis: its activity in relation to sodium balance. Q J Med, 56(220), 485-496. Abstract. Author URL.

Sellars L, Shore AC, Wilkinson R, James OF, Robson V (1981). Sodium status and the renin-angiotensin-aldosterone system in compensated liver disease. Eur J Clin Invest, 11(4), 299-304. Abstract. Author URL.

Irving RJ, Walker BR, Noon JP, Webb DJ, Watt GCM, Shore AC (1971). Microvascular correlates of blood pressure, plasma glucose, and insulin resistance in health. Cardiovascular Research, 5(SUPP1), 271-276. Abstract.

Mahy IR, Shore AC, Tooke JE, Smith LD (1969). Disturbance of peripheral microvascular function in congestive heart failure secondary to idiopathic dilated cardiomyopathy. Cardiovascular Research, 3(4), 939-944. Abstract.

Chapters

Carmichael J, Fadavi H, Ishibashi F, Shore AC, Tavakoli M (2022). Chapter 4 Advances in screening, early diagnosis, and accurate staging of diabetic neuropathy. In (Ed) Diabetic Neuropathy, Elsevier, 47-78.

Thorn C, Shore A (2021). Medical Products Inspired by Biological Oscillators: Intermittent Pneumatic Compression and the Microcirculation. In (Ed) Understanding Complex Systems, 385-399. Abstract.

Conferences

MacDonald W, Casanova F, Gooding K, Aizawa K, Shore A, Khan F (2023). 9 Monocyte chemoattractant protein-1 as a biomarker of vascular dysfunction in patients with type 2 diabetes. Author URL.

Clark C, Jordan A, Anning C, Wilkes L, Ball C, Pamphilon N, Bellenger N, Shore A, Sharp A (2023). ASSOCIATIONS OF INTER-ARM BLOOD PRESSURE DIFFERENCE WITH TREATMENT RESPONSE IN NEWLY TREATED HYPERTENSION. Author URL.

Gooding KM, Rolinska N, Balma S, Brown AF, Ball C, Kelsall C, Mawson D, Aizawa K, Govier A, Gilchrist M, et al (2023). Choriocapillaris perfusion correlates with retinal capillary perfusion in all three retinal plexuses in individuals with type 2 diabetes. Author URL.

Kelsall CJ, Whatmore JL, Kos K, Ball CI, James M, Ling R, Ramsden C, von Lany H, Shore AC, Gooding KM, et al (2023). Microvascular responsiveness to the locally delivered glucagon-like peptide-1 analogue, liraglutide, is impaired in individuals with type 2 diabetes and retinopathy. Author URL.

Jordan AN, Aizawa K, Gooding KM, Llewellyn D, Casanova F, Mawson DM, Gates PE, Adingupu DD, Elyas S, Hope SV, et al (2022). ARTERIAL HAEMODYNAMIC PARAMETERS LINKED TO ARTERIAL PULSATILITY, EXCESS WAVE PROPAGATION AND COGNITIVE FUNCTION. Author URL.

Jordan AN, Aizawa K, Gooding KM, Llewellyn D, Casanova F, Mawson DM, Gates PE, Adingupu DD, Elyas S, Hope S, et al (2022). Arterial haemodynamic parameters linked to arterial pulsatility, excess wave propagation and cognitive function. European Society of Hypertension. 17th - 20th Jun 2022. Abstract.

Gooding K, Casanova F, Ball C, Anning C, Pamphilon N, Ling R, Shore AC (2022). Examining whether Growth Differentiation Factor-15 is Altered in the Early Stages of Diabetic Retinopathy in Individuals with Type 2 Diabetes. Author URL.

Patel J, Shore AC, Kyte H, Aung MM, Ball C, Gooding KM (2022). Mechanisms underlying the microvascular actions of insulin in lean and obese individuals. Author URL.

Ireland P, Old O, Hornby S, Kendall C, Barr H, Shore A, Stone N (2022). Raman Needle Probe Lymph Node Assessment for Oesophageal Cancer: the DOLOMITE Study. Author URL.

Brown AF, Gooding KM, Balma S, Mawson D, Shore AC (2021). Application of Capillary Spacing Analysis into Dermal Capillary Density Assessment: Developmental Methodology. Author URL.

Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Khan F, Colhoun HM, Palombo C, et al (2021). ELEVATED EXCESS PRESSURE INTEGRAL IS ASSOCIATED WITH VASCULAR BIOMARKERS OF SUBCLINICAL ATHEROSCLEROSIS IN OLDER ADULTS. Author URL.

Hellgren KJ, Cox D, Ball C, Shore AC, Gooding KM (2021). Is Visual Function Altered in People with Uncomplicated Type 2 Diabetes or with Early Diabetic Retinopathy?. Author URL.

Rolinska N, Shore AC, Gooding KM (2021). Retinal Optical Coherence Tomography Angiography: Algorithm Development and Repeatability Testing of Novel Non-Invasive Microvascular Markers. Author URL.

Clark C, Boddy K, Warren F, Mcdonagh S, Moore S, Aboyans V, Cloutier L, McManus R, Shore A, Taylor R, et al (2021). SYSTOLIC INTER-ARM BLOOD PRESSURE DIFFERENCE AND COGNITIVE DECLINE: FINDINGS FROM THE INTERPRESS-IPD COLLABORATION. Author URL.

Kelsall CJ, Knight BA, James M, Cox D, Ball C, Anning C, Kos K, Whatmore JL, Shore AC, Gooding KM, et al (2021). Vascular Assessment of Human Abdominal versus Gluteal Subcutaneous Fat Biopsies, from People with or without Type 2 Diabetes, and Their Suitability for Study by Pressure Myography. Author URL.

Clark C, Warren F, Boddy K, McDonagh S, Moore S, Cloutier L, Taylor R, Shore A, McManus R, Aboyans V, et al (2021). Which arm to measure blood pressure: does the higher or lower reading arm best reflect systolic blood pressure? an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration. Author URL.

Riddell A, Kirkwood J, Smallwood M, Winyard P, Knight B, Steer K, Puddicombe L, Romanczuk L, Shore A, Gilchrist M, et al (2020). CAN THE URINARY NITRATE TO CREATININE RATIO BE USED AS a MARKER FOR KIDNEY TRANSPLANT REJECTION?. Author URL.

Shami A, Edsfeldt A, Shore AG, Natali A, Khan F, Nilsson J, Lutgens E, Goncalves I (2020). CD40 levels in plasma are associated with cardiovascular disease and in carotid plaques with a vulnerable plaque phenotype and remodelling. Author URL.

Williams J, Gilchrist M, Fraser D, Strain D, Shore A (2020). CUTANEOUS MICROCIRCULATORY DYSFUNCTION IN PERITONEAL DIALYSIS PATIENTS. Author URL.

Gooding K, Shore AC, Casanova F, Ball C, Wilkes L, Ling R, Agardh E (2020). Examining the Impact of Type 2 Diabetes on Longitudinal Changes in Fovea Thickness. Author URL.

Clark C, Boddy K, Warren F, McDonagh S, Moore S, Aboyans V, Cloutier L, McManus R, Shore A, Taylor R, et al (2020). Systolic inter-arm blood pressure difference and cognitive decline: findings from the INTERPRESS-IPD Collaboration. Author URL.

Gooding K, Chapman D, Casanova F, Ball C, Whatmore JL, Ling R, Shore AC (2019). A PRELIMINARY STUDY EXAMINING ALBUMINURIA, MACULAR THICKNESS AND GLYCOCALYX SHEDDING IN THE EARLY STAGES OF DIABETIC RETINOPATHY IN TYPE 2 DIABETES. Author URL.

Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Khan F, Colhoun HM, Palombo C, et al (2019). ALTERED CENTRAL HAEMODYNAMIC PARAMETERS DERIVED FROM RESERVOIR PRESSURE ANALYSIS: ASSOCIATION WITH BIOMARKERS OF TARGET ORGAN DAMAGE IN OLDER ADULTS. Author URL.

Gooding K, Casanova F, Cox D, Ball C, Aizawa K, Mawson D, Shore A (2019). Association Between Sural Nerve Conductance Amplitude and Skin Microvascular Responsiveness in Individuals with and without Type 2 Diabetes Across the Subclinical Neuropathy Range. Author URL.

Nielsen SH, Goncalves I, Shore A, Natali A, Khan F, Genovese F, Karsdal M, Nilsson J (2019). Endotrophin, a fragment of collagen type VI, is correlated to IMT and associated with cardiovascular events in patients with atherosclerosis and diabetes: the IMI-SUMMIT cohort. Author URL.

Wu C, Borne Y, Rodriguez ML, Duffin KL, Gao R, Melander O, Melander MO, Shore A, Khan F, Natali A, et al (2019). Follistatin-a circulating biomarker for type 2 diabetes. Author URL.

Clark C, Warren F, Boddy K, McDonagh S, Moore S, Cloutier L, Taylor R, Shore A, McManus R, Aboyans V, et al (2019). INTER-ARM BLOOD PRESSURE DIFFERENCE: INSIGHTS INTO AETIOLOGY FROM THE INTERPRESS-IPD COLLABORATION. Author URL.

Clark C, Warren F, Boddy K, McDonagh S, Moore S, Cloutier L, Taylor R, Shore A, McManus R, Aboyans V, et al (2019). Inter-arm blood pressure difference: insights into aetiology from the INTERPRESS-IPD collaboration. Author URL.

Meakin PJ, Tuharska Z, Gooding KM, Casanova F, Shore AC, Ashford MLJ, Khan F (2018). Association between β-amyloid, diabetes and endothelial function in humans. Author URL.

Clark C, Boddy K, Warren F, Mcdonagh S, Taylor R, Aboyans V, Cloutier L, McManus R, Shore A, Campbell J, et al (2018). INTER-ARM DIFFERENCES IN BLOOD PRESSURE AND MORTALITY: INDIVIDUAL PATIENT DATA META-ANALYSIS AND DEVELOPMENT OF a PROGNOSTIC ALGORITHM (INTERPRESSIPD COLLABORATION). Author URL.

Jordan A, Anning C, Ball C, Pamphilon N, Wilkes L, Fulford J, Shore A, Sharp A, Bellenger N (2018). Left ventricular hypertrophy in hypertensive heart disease: early myocardial response to treatment. Author URL.

Aizawa K, Casanova F, Mawson DM, Gooding KM, Strain WD, Gates PE, Ostling G, Nilsson J, Khan F, Colhoun HM, et al (2018). PARAMETERS DERIVED FROM RESERVOIR PRESSURE ANALYSIS INDEPENDENTLY PREDICT CARDIOVASCULAR EVENTS IN a MULTI-CENTRE STUDY OF INDIVIDUALS WITH TYPE 2 DIABETES. Author URL.

Ball C, Casanova F, Shore AC, Anning CM, Cox D, Gooding KM (2018). Participant feedback on strategies implemented to maintain participant engagement in a longitudinal, observational clinical study. Author URL.

Shore AC, Sharp ASP, Anning C, Pamphilon N, Ball C, Clark C, Bellenger NG, Jordan A (2018). Rapid treatment of Grade 2-3 hypertension in previously untreated patients is accompanied by an increase in total and perfused skin capillary density. Author URL.

Jordan A, Anning C, Pamphilon N, Wilkes L, Clark C, Bellenger N, Shore A, Sharp A (2018). Rapid treatment of moderate-to-severe hypertension using a novel nurse-directed protocol is safe and effective. Author URL.

Casanova F, Adingupu DD, Gooding KM, Aizawa K, Gates PE, Elyas S, Shore AC, Strain DW (2017). Association Between Renal Function and Matrix Metalloproteinases in Type 2 Diabetes. Author URL.

Gooding K, Shore AC, Casanova F, Colhoun HM, Looker HC, Leese GP, Agardh E (2017). EXAMINING LONGITUDINAL CHANGES OF MACULAR THICKNESS IN THE EARLY STAGES OF DIABETIC RETINOPATHY. Author URL.

Gooding K, Mayne T, Casanova F, Ball C, Cox D, Ling R, Shore A (2017). Exploring the Relationship Between Retinal Micro-aneurysms with Plasma Levels of Matrix Metal-loproteinases and Growth Factors in Type 2 Diabetes. Author URL.

Jordan A, Anning C, Ball C, Wilkes L, Pamphilon N, Clark C, Shore A, Sharp A (2017). RAPID TREATMENT OF NEWLY-DIAGNOSED MODERATE-SEVERE HYPERTENSION IS SAFE AND EFFECTIVE. Author URL.

Aizawa K, Casanova F, Mawson DM, Gooding KM, Park CM, Elyas S, Adingupu DD, Strain WD, Parker KH, Gates PE, et al (2017). RESERVOIR-PRESSURE ANALYSIS PREDICTS CARDIOVASCULAR EVENTS IN INDIVIDUALS WITH TYPE 2 DIABETES: a SINGLE-CENTRE STUDY. Author URL.

Gooding KM, Shore AC, Ling R, Looker HC, Colhoun HM, Agardh E (2016). Assessment of using a retinal OCT phantom in multi-centre trials assessing macular thickness. Author URL.

Old O, Lloyd G, Isabelle M, Kendall C, Shepherd N, Stone N, Shore A, Barr H (2016). Detection of Barrett's Neoplasia in Oesophageal Cells Using Infrared Spectroscopy. Author URL.

Clark C, Warren F, Boddy K, Taylor R, Shore A, Aboyans V, Cloutier L, McManus R, Campbell J (2016). INTERPRESS-IPD: THE INTER-ARM BLOOD PRESSURE DIFFERENCE INDIVIDUAL PATIENT DATA COLLABORATION. Author URL.

Frost J, Ludeman L, Hillaby K, Gornall R, Lloyd G, Kendall C, Stone N, Shore AC (2016). Infrared spectroscopy for the biomolecular assessment of vulval intraepithelial neoplasia and lichen sclerosus found in association with squamous cell carcinoma. Author URL.

Frost J, Ludeman L, Hillaby K, Kendall C, Shore AC, Stone N (2016). Infrared spectroscopy for the molecular evaluation of lichen sclerosus and vulval intraepithelial neoplasia found in conjunction with vulval squamous cell carcinoma. Author URL.

Aizawa K, Casanova F, Mawson D, Elyas S, Adingupu DD, Gooding KM, Strain WD, Park CM, Parker KH, Gates PE, et al (2016). RESERVOIR-PRESSURE ANALYSIS IN TYPE 2 DIABETES INDIVIDUALS WITH CARDIOVASCULAR DISEASE. Author URL.

Frost J, Ludeman L, Hillaby K, Gornall R, Lloyd G, Kendall C, Shore AC, Stone N (2016). Raman spectroscopy and multivariate analysis for the non invasive diagnosis of Vulval lichen sclerosus. Author URL.

Ramalli A, Byra M, Dallai A, Palombo C, Aizawa K, Sbragi S, Shore A, Tortoli P (2015). A Multiparametric Approach Integrating Vessel Diameter, Wall Shear Rate and Physiologic Signals for Optimized Flow Mediated Dilation Studies. Author URL.

Kos K, McCulloch LJ, Ward R, Joshi S, Sjoholm K, Pitt A, Gooding KM, Shore AC, Carlsson LMS (2015). Adipose tissue response to GLP-1 analogue-induced weight loss. Author URL.

Elyas SP, Adingupu D, Aizawa K, Shore AC, Strain WD, Gates PE (2015). Cerebral haemodynamics are different in patients with and without cerebral white matter hyperintensities. Author URL.

Casanova F, Adingupu D, Gooding K, Strain D, Shore A (2015). DOES GLYCAEMIC CONTROL AFFECT MICROVASCULAR FUNCTION INDEPENDENT OF BLOOD PRESSURE IN TYPE 2 DIABETES?. Author URL.

Swarbrick D, Bellenger N, Kannoly S, Gosling O, Hossain E, Shore A, Chawner R, Ripley D (2015). EVALUATION OF CARDIAC RISK USING DOBUTAMINE CARDIAC STRESS MAGNETIC REASONANCE PRIOR TO RENAL TRANSPLANTATION. Author URL.

Frost J, Ludeman L, Hillaby K, Kendall C, Shore AC, Stone N (2015). FOURIER TRANSFORM INFRARED SPECTROSCOPY IN THE BIOMOLECULAR ASSESSMENT OF VULVAL INTRAEPITHELIAL NEOPLASIA AND LICHEN SCLEROSUS FOUND IN ASSOCIATION WITH VULVAL SQUAMOUS CELL CARCINOMA. Author URL.

Shore A (2015). FROM CAPILLARY TO END ORGAN DAMAGE. Author URL.

Gooding K, Shore A (2015). LDF MEASUREMENT - FROM THE LAB TO THE BEDSIDE. Author URL.

Gooding K, Aung MM, Kos K, Shore A (2015). MICROVASCULAR ACTIONS OF GLUCAGON-LIKE PEPTIDE-1 AND ITS ANALOGUES IN LEAN AND OBESE PARTICIPANTS AND PARTICIPANTS WITH TYPE 2 DIABETES. Author URL.

Old OJ, Lloyd G, Almond M, Kendall C, Barr H, Shore A, Stone N (2015). NON-ENDOSCOPIC SCREENING FOR BARRETT'S OESOPHAGUS: IDENTIFYING NEOPLASIA WITH INFRARED SPECTROSCOPY. Author URL.

Thorn CE, Knight B, Laura MJ, Patel B, Shore A, Kos K (2015). OBSTRUCTIVE SLEEP APNOEA SYNDROME AFFECTS BLOOD FLOW AND OXYGENATION OF ADIPOSE TISSUE. Author URL.

Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Mawson D, Shore AC, Strain WD, Gates PE (2015). PP.20.26.

Gooding KM, Shore AC, Ling R, Casanova F, Looker HC, Agardh E (2015). Regional differences in macular thickness in the early stages of diabetic retinopathy in type 2 diabetes. Author URL.

Gooding KM, Shore AC, Ling R, Agardh E (2014). An evaluation of different methods of normalising fovea thickness measurements from optical coherence tomography instruments. Author URL.

Clark C, Casanova F, Gooding K, Pamphilon N, Aizawa K, Mawson D, Adingupu D, Ball C, Worthington F, Elyas S, et al (2014). Inter-arm blood pressure difference and differences in arterial stiffness. Author URL.

Elyas S, Shore AC, James MA, Peters A, Eastwood H, Keenan S, Stewart J, Strain WD (2014). Microalbuminuria could predict critical carotid artery stenosis in patients presenting with TIA and minor strokes. Author URL.

Strain WD, Chaturvedi NC, Rajkumar C, Bulpitt CJ, Nihoyannopoulos P, Hughes AD, Shore AC (2009). Are Ethnic Differences in Left Ventricular Concentric Remodelling in Those with Diabetes Due to Differences in Microvascular Function?. Author URL.

Whiteman M, Whatmore JL, Skinner K, Ball C, Gooding KM, Shore AC (2009). Plasma hydrogen sulphide: correlations with clinical indices of micro- and macrovascular function, obesity, metabolic syndrome and type II diabetes. Author URL.

Moger J, Winlove CP, Shore AC, Matcher SJ (2005). The effect of multiple scattering upon velocity profiles measured using Doppler OCT. Optical Coherence Tomography and Coherence Techniques II.

Noon JP, Shore AC, Haynes WG, Walker BR, Webb DJ (1995). The effects of brachial artery infusion of N(G)-monomethyl-L-arginine on microvascular blood flow in healthy volunteers.

TOOKE JE, SHORE AC, SANDEMAN DD (1992). THE EVOLUTION OF PERIPHERAL MICROVASCULAR HEMODYNAMIC-CHANGES IN HUMAN DIABETES. Author URL.

Spiegel M, Vesti B, Shore A, Franzeck UK, Bollinger A (1991). Pressure measurements in the lymph capillaries of the human skin.

External Engagement and Impact

Awards

The Queen’s Anniversary Prize for Higher and Further Education 1996, Diabetes and vascular health education and research: microvascular processes and associated work.

Committee/panel activities

Official positions

President, British Microcirculation Society
Associate Director Experimental Medicine, Diabetes Co-ordinating Centre, UK Clinical Research Network
Clinical Associate Editor, Microcirculation

Membership of committees/boards

World Microcirculation International Liaison Committee
European Society for Microcirculation, Strategy committee
Diabetes UK: Science and Research Advisory Group, Research committee, Studentship panel, Fellowship panel
UK Clinical Research Network: Clinical Studies Advisory Group Member, Diabetes Operational Steering Group Member, Diabetes
Diabetes and Wellness Foundation, Research Advisory Board
NIHR Clinical Research Network Industry Strategy Group
Transforming Ageing National Advisory Panel
Health Research Board Ireland
European Society for Cardiology Council for Basic Cardiovascular Science
Royal Devon and Exeter Hospital Research Advisory Panel member

Editorial responsibilities

Microcirculation, Clinical Associate Editor - 2010-date
Journal of Vascular Research, member of editorial board - 1998-date

Teaching

Academic tutor for BMBS year 1 and 2

Professional Training year provider for BSc Medical Sciences

PhD/MPhil supervisor, currently 9 students

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