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Clinical and Biomedical Sciences

 Alice Franklin

Alice Franklin

Graduate Research Assistant

 A.Franklin@exeter.ac.uk

 


Overview

Alice graduated from the University of Exeter with a BSc Honours degree in Natural Sciences, during which she developed a strong interest in the use of bioinformatics to understand human health and disease.

Her final year undergraduate research project focused on the evaluation of a novel statistical deconvolution tool for epigenetics research. After graduation, she joined the Complex Disease Epigenomics Group as a graduate research assistant where she is focusing on the DNA methylation changes that occur during human fetal development.

Qualifications

  • BSc (First Class Hons) Natural Sciences, University of Exeter

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Publications

Journal articles

Hannon E, Mill J, Dempster E, Walker E, Franklin A, Chioza B, Commins G, Davies J, Burrage J (2024). Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles. BMC Biology
Bamford RA, Leung SK, Jeffries AR, Franklin A, Commin G, Davies J, Dempster E, Hannon E, Mill J (2023). 59. ULTRA-DEEP LONG READ TRANSCRIPTOME SEQUENCING REVEALS DRAMATIC ISOFORM DIVERSITY ACROSS HUMAN CORTEX DEVELOPMENT: RELEVANCE FOR GENETIC STUDIES OF PSYCHIATRIC DISORDERS. European Neuropsychopharmacology, 75
Mill J, Hannon E, Dempster E, Franklin A, Burrage J, Davies J, Chioza B, Commin G, Jeffries AR, Bamford RA, et al (2023). W76. CELL-SPECIFIC METHYLOMIC VARIATION IN NEURODEVELOPMENT AND SCHIZOPHRENIA. European Neuropsychopharmacology, 75, s144-s145.
Davies J, Franklin A, Walker E, Owens N, Bray N, Bamford RA, Commin G, Chioza B, Burrage J, Dempster E, et al (2022). 1. DEVELOPMENTAL TRAJECTORIES OF DNA METHYLATION IN NEURAL CELL POPULATIONS IN HUMAN CORTEX AND LINKS TO NEURODEVELOPMENTAL DISORDERS. European Neuropsychopharmacology, 63
Steg LC, Shireby GL, Imm J, Davies JP, Franklin A, Flynn R, Namboori SC, Bhinge A, Jeffries AR, Burrage J, et al (2021). Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons. Mol Brain, 14(1). Abstract.  Author URL.
Howell L, Osborne E, Franklin A, Hébrard É (2021). Pattern Recognition of Chemical Waves: Finding the Activation Energy of the Autocatalytic Step in the Belousov-Zhabotinsky Reaction. J Phys Chem B, 125(6), 1667-1673. Abstract.  Author URL.
Steg LC, Shireby GL, Imm J, Davies JP, Franklin A, Flynn R, Namboori SC, Bhinge A, Jeffries AR, Burrage J, et al (2020). Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons. Abstract.

Conferences

Davies J, Franklin A, Commin G, Walker E, Policicchio S, Jeffries A, Burrage J, Chioza B, Liu J, Bray N, et al (2021). CELL-TYPE-SPECIFIC PATTERNS OF DNA METHYLATION IN THE DEVELOPING HUMAN BRAIN.  Author URL.
Yap C, Luo C, Vellame DS, Bhattacharya A, Franklin A, Mill J, Gandal M (2021). GENETIC CONTROL OF DECONVOLVED BRAIN CELL-TYPES.  Author URL.

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