Professor Noel Morgan
Vice-Dean: Research (Interim), Professor of Endocrine Pharmacology; Director - Institute of Biomedical & Clinical Science
Professor Morgan has a background in cellular pharmacology and his research career has focussed principally on the (patho)physiology of the pancreatic beta-cell biology in the context of both type 1 and type 2 diabetes. Within the University of Exeter Medical School he leads a team studying the regulation of beta-cell function and viability with the aim to understand how dysfunction and loss of viability lead to clinical disease. His research team has made important recent contributions to the understanding of insulitis (a process of immune-mediated attack) in human pancreas and to the role of a group of common viruses (enteroviruses) as potential mediaotrs of beta-cell loss in type 1 diabetes. He also serves as Director of the Institute of Biomedical and Clinical Science and assists in developing the strategic vision of the Institute as well as the achievement of these goals. This involves resource allocation, strategic planning, recruitment, undertaking staff appraisals and facilitation of the career aspirations of staff at all levels. He is also Director of Postgraduate Research within the Medical School and, in this capacity, chairs the School's Research Degrees committee. He has oversight of the approval and appointment of postgraduate research students as well as the monitoring of their progress, their skill development portfolio and ultimate thesis completion and examination.
Broad research specialisms
His team's research specialisms include the monitoring and assessment of cell function and viability using in vitro approaches; the manipulation of intracellular signalling pathways using both pharmacological and molecular biological approaches; and the application of immunological methods to understand disease pathology in relevant histological samples.
- B.Sc. (Hons)
Noel Morgan began his research career studying islet biology at University of Leicester and then undertook postdoctoral work on the hormonal control of liver glycogenolysis at Vanderbilt University (Nashville, TN). He subsequently developed an independent research programme in islet biology while on the faculty of Keele University (UK). Noel was awarded the inaugural Albert E. Renold Fellowship of EASD in 1990 to work in the laboratory of Robert J Lefkowitz (2012 Nobel laureate) at Duke University, Durham, NC studying adrenoceptor signalling in beta-cells. He was appointed to a Personal Chair at Keele University in 1993 and moved to University of Exeter, in 2002, as Professor of Endocrine Pharmacology. At Exeter, his group has pursued parallel studies on signaling mechanisms regulating β-cell function and viability as well as factors that underlie the loss of β-cells in type 1 diabetes. The latter has been sustained by a long and productive collaboration with Prof Alan Foulis and, together with Dr Sarah Richardson, the team has contributed to the understanding of insulitis in humans and to the role of enteroviruses as potential mediators of islet autoimmunity.
Secretary contact details: Nikki Archer, +44 (0) 1392 408215
|Tel||+44 (0) 1392 408300|
|Address||University of Exeter Medical School|
RD&E Hospital Wonford